Laboratory News and Research

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Precisely mapped allosteric binding site will facilitate design of drugs with minimal side effects

Structural biologists at Cold Spring Harbor Laboratory (CSHL) have obtained a precise molecular map of the binding site for an allosteric inhibitor in a subtype of the NMDA (N-methyl-D-aspartate) receptor, which is commonly expressed in brain cells.

17 Jun 2011

Innovative adult stem cell approach could help eliminate obesity

Innovative adult stem cell research by scientists at The University of Texas Health Science Center at Houston could aid efforts to apply the brakes to stem cells that produce the type of fat ringing the waists of millions. Research appeared today online ahead of the print issue of Cell Stem Cell.

17 Jun 2011

Snack-based diet can increase risk of obesity

A high-fat diet can be bad for your health. However, a snack-based "cafeteria"-style diet of highly palatable, energy-dense foods is even worse, according to new research.

17 Jun 2011

UTHealth receives $1M FEMA grant to examine link between Ad-36 infection, obesity

Researchers at The University of Texas Health Science Center at Houston (UTHealth) have been awarded nearly $1 million to investigate Adenovirus-36 (Ad-36) infection as a novel risk factor for obesity.

17 Jun 2011

Scientists uncover how immune system responds to invading anthrax bacteria

Scientists at the University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences have uncovered how the body's immune system launches its survival response to the notorious and deadly bacterium anthrax.

17 Jun 2011

Anxiety hinders detection during search for multiple objects

A person scanning baggage or X-rays stands a better chance of seeing everything they're searching for if they aren't feeling anxious, according to a new laboratory experiment.

17 Jun 2011

New weapon in the fight against cancer

A cancer diagnosis is not necessarily a death sentence. There are now quite a number of possibilities to treat cancer. In addition to radiotherapy and chemotherapy, so-called radionuclide treatment has also become an important component in the fight against the mutated cells. It involves injecting radioactive elements, so-called nuclides, into the patient's circulatory system.

17 Jun 2011

First genetic, biochemical tests for Idiopathic Infantile Hypercalcemia

A breakthrough in genetic research has uncovered the defect behind a rare hereditary children's disease that inhibits the body's ability to break down vitamin D. This discovery has led researchers to develop the first genetic and biochemical tests that positively identify the disease.

17 Jun 2011

New Australian drug shows positive response in patients with multiple myeloma blood cancer

Australian monoclonal antibody company, Immune System Therapeutics Limited (IST), today announced it would double patient recruitment in its Phase II trial for a breakthrough antibody treatment for terminal blood cancer.

16 Jun 2011

Researchers reveal why anti-androgen therapy may fail in men with prostate cancer

Cancer is crafty. When one avenue driving its growth is blocked by drugs targeting that path, the malignancy often creates a detour, finding an alternative route to get around the roadblock.

16 Jun 2011

University of Houston chemist develops two different materials against E. coli

A University of Houston (UH) chemist who is developing materials for detecting and repelling E. coli has published papers in two high-impact journals this month.

16 Jun 2011

DiagnoCure receives new U.S. patent for PCA3 prostate cancer biomarker portfolio

DiagnoCure, Inc., a life sciences company commercializing high‐value cancer diagnostic tests and delivering laboratory services, today reported the issuance of a new U.S. patent, which represents a significant addition to DiagnoCure's PCA3 prostate cancer biomarker portfolio.

16 Jun 2011

Platelet Derived Growth Factor Receptor-beta plays key role in onset of obesity

A new study from Mount Sinai School of Medicine has found that a cellular signaling pathway governs the differentiation of cells into fat tissue or smooth muscle, which lines the vascular system. Engaging this signaling pathway and its capacity to govern cell differentiation has important implications in preventing obesity and cardiovascular disease.

16 Jun 2011

Cambridge Biomedical, Neogenix partner to develop ELISA assays for pancreatic and colorectal cancer

Neogenix Oncology, Inc. is pleased to announce it has signed an agreement with Cambridge Biomedical, Inc, based in Boston, MA, for the development of its pancreatic and colorectal cancer diagnostic serum ELISA assays.

16 Jun 2011

ISSCR honors UCSF cancer scientist with 2011 Outstanding Young Investigator Award

UCSF's Robert Blelloch, MD, PhD, has received the 2011 Outstanding Young Investigator Award from the International Society for Stem Cell Research, for his pioneering research on the role of molecular tools known as microRNAs in embryonic stem cells and cancer.

16 Jun 2011

NIH awards $20 million research grant to University of Kentucky

The National Institutes of Health (NIH), the largest government funding source for biomedical research in the United States, has awarded $20 million to the University of Kentucky to move research discoveries to health care solutions more quickly.

15 Jun 2011

Scientists zero in on dose levels of "sacred mushroom"

Scientists at the Johns Hopkins University School of Medicine have zeroed in on the dose levels of the "sacred mushroom" chemical capable of yielding positive, life-changing experiences, while minimizing the chance of transient negative reactions in screened volunteers under supportive, carefully monitored conditions.

15 Jun 2011

QIAGEN to acquire Ipsogen

QIAGEN N.V. has made an offer and entered into exclusive negotiations to purchase a 47% initial stake in Ipsogen S.A. and subsequently make a public offer to fully acquire a global leader in molecular profiling and personalized healthcare diagnostics for a broad range of hematological cancers.

From QIAGEN Manchester Limited 15 Jun 2011

Study investigates effects of dopamine replacement therapy on cognition in patients with Parkinson's

Dopamine replacement therapy, which is used to manage motor symptoms associated with Parkinson's disease, can, at times, adversely affect cognition.

15 Jun 2011

Scientists use time-lapse technique to create lab model for ovarian cancer

Scientists at Harvard University have created a laboratory model using time-lapse video microscopic technology that allows observation of early stages of ovarian cancer metastasis.

15 Jun 2011

Laboratory News and Research

Precisely mapped allosteric binding site will facilitate design of drugs with minimal side effects

Innovative adult stem cell approach could help eliminate obesity

Snack-based diet can increase risk of obesity

UTHealth receives $1M FEMA grant to examine link between Ad-36 infection, obesity

Scientists uncover how immune system responds to invading anthrax bacteria

Anxiety hinders detection during search for multiple objects

New weapon in the fight against cancer

First genetic, biochemical tests for Idiopathic Infantile Hypercalcemia

New Australian drug shows positive response in patients with multiple myeloma blood cancer

Researchers reveal why anti-androgen therapy may fail in men with prostate cancer

University of Houston chemist develops two different materials against E. coli

DiagnoCure receives new U.S. patent for PCA3 prostate cancer biomarker portfolio

Platelet Derived Growth Factor Receptor-beta plays key role in onset of obesity

Cambridge Biomedical, Neogenix partner to develop ELISA assays for pancreatic and colorectal cancer

ISSCR honors UCSF cancer scientist with 2011 Outstanding Young Investigator Award

NIH awards $20 million research grant to University of Kentucky

Scientists zero in on dose levels of "sacred mushroom"

QIAGEN to acquire Ipsogen

Study investigates effects of dopamine replacement therapy on cognition in patients with Parkinson's

Scientists use time-lapse technique to create lab model for ovarian cancer

Lab Diagnostics and Automation - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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