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Abnormal clock gene coordination observed in tissues of Alzheimer's patients

Twenty-four hour cycles, known as circadian rhythms, are important for proper body functions, including for normal brain function and mental health. Disruptions of circadian rhythms and sleep-wake cycles have been observed in patients with Alzheimer's disease. A new study by Douglas Institute researchers unravels a possible basis for these perturbations.

28 Apr 2011

Positive results from Shire's Vyvanse clinical trial in schizophrenia

Shire plc, the global specialty biopharmaceutical company, today announced positive results from a signal-finding study of Vyvanse(R) Capsules assessing its effect in a prospective examination of adults with negative symptom predominant schizophrenia.

28 Apr 2011

Five Loyola employees donate kidneys to complete strangers

Loyola University Medical Center is believed to be the first organization in the country, and perhaps the world, in which five employees have each donated kidneys to complete strangers with no strings attached.

28 Apr 2011

New control point for suppressing cancer cell growth

Dana-Farber Cancer Institute scientists have discovered new details of how cancer cells escape from tumor suppression mechanisms that normally prevent these damaged cells from multiplying. They also demonstrated a potential link between this cell proliferation control mechanism and the cognitive deficits caused by Down syndrome.

28 Apr 2011

Stop malaria by taking precautions before travelling to endemic zones

More than half of UK malaria cases are seen in people visiting friends and relatives in West Africa and India. The World Health Organization (WHO) estimates there were 243 million cases of malaria in 2008 and almost a million deaths worldwide.

28 Apr 2011

Scientists weaken long-term memory

Could veterans of war, rape victims and other people who have seen horrific crimes someday have the traumatic memories that haunt them weakened in their brains? In a new study, UCLA life scientists report a discovery that may make the reduction of such memories a reality.

28 Apr 2011

New nanoparticle imaging agent can help diagnose heart disease, breast cancer

Scientists are reporting development of a process for producing large quantities of a much-needed new imaging agent for computed tomography scans in heart disease, breast cancer and other diseases, and the first evidence that the material is safe for clinical use.

28 Apr 2011

Promising pain medication may decrease ability to fight off sepsis

Pain researchers from the Sheikh Zayed Institute for Pediatric Surgical Innovation at Children's National Medical Center have discovered that resiniferatoxin, a drug that has shown early promise as an option for chronic, severe pain sufferers, may decrease the body's ability to fight off bacterial infections, particularly sepsis.

27 Apr 2011

Thermo Fisher revenues increase 4% to $2.72 billion for first quarter 2011

Thermo Fisher Scientific Inc., the world leader in serving science, today reported its financial results for the first quarter ended April 2, 2011.

From Thermo Fisher Scientific Inc. 27 Apr 2011

New discoveries on polycystin-1 can lead to novel kidney disease treatment

Two discoveries at UC Santa Barbara point to potential new drug therapies for patients with kidney disease. The findings are published in this week's issue of the Proceedings of the National Academy of Sciences.

27 Apr 2011

Biomagnetics accepts Los Alamos National Labs' optical biosensor for disease diagnosis

Biomagnetics Diagnostics Corp., a developer of revolutionary diagnostic systems and technology for HIV, hepatitis, tuberculosis, cholera and malaria detection, and other innovative technologies, today announced it has accepted delivery of the world's first integrated optical biosensor for disease diagnosis.

27 Apr 2011

Biologists determine molecular structure of GluN2D receptor subunit

Structural biologists at Cold Spring Harbor Laboratory in collaboration with colleagues at Emory University have determined the molecular structure of a key portion, or subunit, of a receptor type commonly expressed in brain cells.

27 Apr 2011

Major breakthrough in understanding of amyotrophic lateral sclerosis

Brandeis researchers have made a significant advance in the effort to understand amyotrophic lateral sclerosis by successfully reversing the toxicity of the mutated protein in the familial type of the disease.

27 Apr 2011

Study finds gender difference in immune responses to PTSD

Men and women had starkly different immune system responses to chronic post-traumatic stress disorder, with men showing no response and women showing a strong response, in two studies by researchers at the San Francisco VA Medical Center and the University of California, San Francisco.

27 Apr 2011

Heparan sulfate may have a key role in tumor-spurred lymphatic vessel growth

Cancer has a mighty big bag of tricks that it uses to evade the body's natural defense mechanisms and proliferate. Among those tricks is one that allows tumor cells to turn the intricate and extensive system of lymphatic vessels into something of a highway to metastasis. Yet research unveiled this week may aid in the development of therapeutics that will put the brakes on such cancer spread, and the researchers who completed the study say the findings may extend to other lymphatic disorders.

27 Apr 2011

ISC-4 topical compound may prevent skin cancer lesion formation

While incidents of melanoma continue to increase despite the use of sunscreen and skin screenings, a topical compound called ISC-4 may prevent melanoma lesion formation, according to Penn State College of Medicine researchers.

27 Apr 2011

Magnetic 'nanobeads' help detect chemical and biological agents

Researchers at Oregon State University have found a way to use magnetic "nanobeads" to help detect chemical and biological agents, with possible applications in everything from bioterrorism to medical diagnostics, environmental monitoring or even water and food safety.

27 Apr 2011

AAN honors BIDMC neurologist with Epilepsy Award

Bernard Chang, MD, a member of the Department of Neurology at Beth Israel Deaconess Medical Center and Assistant Professor of Neurology at Harvard Medical School, received the Dreifuss-Penry Epilepsy Award at the 63rd Annual Meeting of the American Academy of Neurology, held recently in Honolulu, HI.

27 Apr 2011

Motor regulatory protein can block human ovarian tumor growth

A motor regulatory protein can block human ovarian tumor growth, leading to eventual cancer cell death and possible new therapies to treat the disease, according to Penn State College of Medicine researchers.

27 Apr 2011