Laboratory News and Research

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Rapid prototyping of new tissues and organs

A more effective way to build plastic scaffolds on which new tissues and even whole organs might be grown in the laboratory is being developed by an international collaboration between teams in Portugal and the UK.

18 Jun 2009

Antibiotics diminish diversity of helpful gutmicrobes

It's common knowledge that a protective navy of bacteria normally floats in our intestinal tracts. Antibiotics at least temporarily disturb the normal balance. But it's unclear which antibiotics are the most disruptive, and if the full array of "good bacteria" return promptly or remain altered for some time.

18 Jun 2009

$7.7 billion for H1N1 included in “House War-Spending Bill”

The U.S. House of Representatives on Tuesday narrowly passed a $106 billion war-funding bill, which "included 7.7 billion to help the nation prepare for an outbreak of the H1N1 virus, the so-called swine flu," the Washington Times reports (Rowland, Washington Times, 6/17). The spending bill will now move to the Senate for consideration (Pelofsky, Reuters, 6/16).

18 Jun 2009

Globe and Mail examines GlaxoSmithKline's RTS,S malaria vaccine trials in Kenya

The Globe and Mail examines GlaxoSmithKline's RTS,S malaria vaccine trials in Kilifi, Kenya – one of the sites where the experimental vaccine is being tested. "The stories of the mothers of Kilifi open a window on the challenges faced by researchers as they build a trial that will include more than 16,000 babies from 11 sites spread across sub-Saharan Africa," the Globe and Mail reports.

18 Jun 2009

Animal model for human gambling

UBC researchers have created the world's first animal laboratory experiment to successfully model human gambling. The advance will help scientists develop and test new treatments for gambling addictions, a devastating condition that affects millions worldwide.

17 Jun 2009

Genome-wide map shows precisely where microRNAs do their work

MicroRNAs are the newest kid on the genetic block. By regulating the unzipping of genetic information, these tiny molecules have set the scientific world alight with such wide-ranging applications as onions that can't make you cry and therapeutic potential for new treatments for viral infections, cancer and degenerative diseases. But the question remains: How do they work?

17 Jun 2009

New diagnostic technique detects possible Alzheimer's biomarker in blood

A new diagnostic technique which may greatly simplify the detection of Alzheimer's disease has been discovered by researchers at McGill University and the affiliated Lady Davis Institute for Medical Research at Montreal's Jewish General Hospital (JGH).

17 Jun 2009

Novel light-sensitive compounds show promise for photodynamic cancer therapy

Chemists at the University of California, Santa Cruz, have developed novel compounds that show promise for photodynamic cancer therapy, which uses light-activated drugs to kill tumor cells.

17 Jun 2009

Bio-friendly nanocrystals allow study of biomolecules one at a time

Researchers at the U.S. Department of Energy's (DOE) Lawrence Berkeley National Laboratory have created bright, stable and bio-friendly nanocrystals that act as individual investigators of activity within a cell.

17 Jun 2009

Taxol-carrying nanoparticles

Nanoparticles specially engineered by University of Central Florida Assistant Professor J. Manuel Perez and his colleagues could someday target and destroy tumors, sparing patients from toxic, whole-body chemotherapies.

17 Jun 2009

Minimally invasive treatment of brain tumors on the horizon

Duke University engineers have taken a first step toward a minimally invasive treatment of brain tumors by combining chemotherapy with heat administered from the end of a catheter.

17 Jun 2009

Discovery of genetic markers to help fight diabetes

Translational Genomics Research Institute (TGen) scientists have identified five genetic biomarkers that could help lead to improved treatments, with fewer side-effects, for patients with diabetes.

17 Jun 2009

Simple blood test detects molecular marker of aging in humans

In 2004, researchers at the University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center announced a crucial discovery in the understanding of cellular aging. They found that as cells and tissues age, the expression of a key protein, called p16INK4a, dramatically increases in most mammalian organs. Because p16INK4a is a tumor suppressor protein, cancer researchers are interested in its role in cellular aging and cancer prevention.

17 Jun 2009

Plant microbe shares features with drug-resistant pathogen - implications for biotech

An international team of scientists has discovered extensive similarities between a strain of bacteria commonly associated with plants and one increasingly linked to opportunistic infections in hospital patients. The findings suggest caution in the use of the plant-associated strain for a range of biotech applications. The genetic analysis was conducted in part at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory, and will be published in the July 2009 issue of Nature Reviews Microbiology, now available online.

16 Jun 2009

Jeffrey Friedman receives Shaw Prize for discovery of leptin

Jeffrey M. Friedman, Marilyn M. Simpson Professor and head of the Laboratory of Molecular Genetics at Rockefeller University, has received the 2009 Shaw Prize in Life Science and Medicine. The prize was announced today by the Hong Kong-based Shaw Prize Foundation.

16 Jun 2009

Cannabis smoke damages DNA – cancer risks

A new study published by University of Leicester researchers has found "convincing evidence" that cannabis smoke damages DNA in ways that could potentially increase the risk of cancer development in humans.

16 Jun 2009

Genomic discovery: Protecting kidney function during heart failure

Mayo Clinic cardiology researchers have found a peptide that helps preserve and improve kidney function during heart failure, without affecting blood pressure. Earlier variations of this peptide caused blood pressure to drop limiting the potential benefits to the kidneys. The findings appear in the current Proceedings of the National Academy of Sciences.

16 Jun 2009