Laboratory News and Research

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Risk of Bisphenol A in plastic products, Q & A's

Bisphenol A, an estrogenlike compound in polycarbonate plastics and epoxy resin, has been popping up in the news a lot lately.

30 Apr 2008

Getting to the roots of breast cancer

The lesson learned in eradicating dandelions from your yard could apply in treating breast cancer as well, said researchers from Baylor College of Medicine in Houston in a report that appears online today in the Journal of the National Cancer Institute.

29 Apr 2008

Novel newborn screening kits developed by NovaUCD-based Enzolve Technologies

Enzolve Technologies, a UCD spin-out company based at NovaUCD the Innovation and Technology Transfer Centre at University College Dublin, has received substantial investment from Enterprise Ireland under the National Development Plan (2007-2013) and private investors.

29 Apr 2008

Scientists determine drug target for the most potent botulinum neurotoxin

Botulinum neurotoxin - responsible for the deadly food poisoning disease botulism and for the beneficial effects of smoothing out facial wrinkles - can also be used as a dreaded biological weapon. When ingested or inhaled, less than a billionth of an ounce can cause muscle paralysis and eventual death. Although experimental vaccines administered prior to exposure can inhibit the destructive action of this neurotoxin - the most deadly protein known to humans - no effective pharmacological treatment exists.

29 Apr 2008

Human protein may offer novel target for blocking HIV infection

A research group supported by the National Institutes of Health (NIH) has uncovered a new route for attacking the human immunodeficiency virus (HIV) that may offer a way to circumvent problems with drug resistance. In findings published today in the online edition of the Proceedings of the National Academy of Sciences, the researchers report that they have blocked HIV infection in the test tube by inactivating a human protein expressed in key immune cells.

29 Apr 2008

Making GNA for nanotechnology

In the rapid and fast-growing world of nanotechnology, researchers are continually on the lookout for new building blocks to push innovation and discovery to scales much smaller than the tiniest speck of dust.

29 Apr 2008

Aspirin-like compounds (salicylates) increase insulin secretion in otherwise healthy obese people

Aspirin-like compounds (salicylates) can claim another health benefit: increasing the amount of insulin produced by otherwise healthy obese people. Obesity is associated with insulin resistance, the first step toward type 2 diabetes.

29 Apr 2008

Tests monitoring viral loads, CD4+ count do not significantly affect survival rates among HIV-positive people

Survival rates among HIV-positive people who undergo routine viral load and CD4+ T cell counts were nearly the same as those who do not receive the tests, according to a study published on Friday in the journal Lancet, the CP/Google.com reports (CP/Google.com, 4/24).

28 Apr 2008

Researchers identify new genes that help predict breast cancer outcomes

Not a day goes by without a new story about the environment. Although we often consider the environment on a global scale, cells in our body also have to contend with environmental factors.

28 Apr 2008

Scientists find distinct kind of stem cells in the pituitary gland

A team of researchers led by scientists at Cold Spring Harbor Laboratory have for the first time identified stem cells that allow the pituitary glands of mice to grow even after birth.

28 Apr 2008

New route discovered for attacking the human immunodeficiency virus

28 Apr 2008

Scientists explore brain's reaction to potent hallucinogen

Brain-imaging studies performed in animals at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory provide researchers with clues about why an increasingly popular recreational drug that causes hallucinations and motor-function impairment in humans is abused.

28 Apr 2008

Scientists discover 4th major set of common genetic variants linked to risk of estrogen receptor-positive breast cancer

Scientists from deCODE genetics report the discovery of two common single-letter variants (SNPs) on chromosome 5 of the human genome that are associated with risk of estrogen receptor-positive (ER+) breast cancer.

27 Apr 2008

3D view of neurons provided by new technique

A new technique that marries a fast-moving laser beam with a special microscope that look at tissues in different optical planes will enable scientists to get a three-dimensional view of neurons or nerve cells as they interact, said Baylor College of Medicine scientists in a report that appears in the journal Nature Neuroscience.

27 Apr 2008

FDA official says agency cannot ensure safety of all medications sold in U.S.

Janet Woodcock, director of the Center for Drug Evaluation and Research at FDA, on Thursday at a Senate hearing said that the number of medication ingredients manufactured abroad limits the ability of the agency to ensure the safety of all treatments sold in the U.S., CQ HealthBeat reports (Carey, CQ HealthBeat, 4/24).

26 Apr 2008