Laboratory News and Research

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Wrapping version of Gleevec fights drug-resistant cancer

A new study highlighted on the cover of this week's issue of Cancer Research finds that the anti-cancer drug Gleevec? is far more effective against a drug-resistant strain of cancer when the drug wraps the target with a molecular bandage that seals out water from a critical area.

2 May 2007

Culture can alter the brain's perceptive mechanisms

Researchers in Illinois and Singapore have found that the aging brain reflects cultural differences in the way that it processes visual information.

2 May 2007

Combination treatment cures mice of a very aggressive human breast tumor

A combination of three different drugs that block the HER-2 receptor, a critical cellular growth signal for some breast cancers, eradicated aggressive breast tumors in mice and could point the way toward developing better treatments inpatients, said researchers from the Breast Center at Baylor College of Medicine in a report that appears today in the Journal of the National Cancer Institute.

2 May 2007

Gene therapy used to try and cure type of blindness

A team of doctors from Moorfields Eye Hospital and University College London (UCL) have carried out world's first eye operations using gene therapy to try to cure a serious eye disorder.

2 May 2007

VivoMetrics receives US patent for cough identification system

VivoMetrics has announced that the United States Patent Office has granted the company a new patent for its cough identification system algorithm.

1 May 2007

New interactive map shows spread of avian flu virus

Scientists here have designed a new, interactive map of the spread of the avian flu virus (H5N1) that for the first time incorporates genetic, geographic and evolutionary information that may help predict where the next outbreak of the virus is likely to occur.

1 May 2007

Simvastatin may help sufferers with Alzheimer's

Treatment with Simvastatin, one of the statin drugs widely used for lowering cholesterol in humans, significantly improved spatial memory - how to navigate a water maze - in mice genetically bred to have an Alzheimer's like disease.

1 May 2007

Smelling for first time results from knowing abnormalities in congenital loss of smell

New discoveries about the biochemical basis of the majority of cases of the congenital inability to smell any odor, no matter how strong, have enabled their discoverer, Dr. Robert I. Henkin, director of The Taste and Smell Clinic in Washington, DC, to treat such patients, enabling them to smell something for the first time in their lives.

1 May 2007

Caution against over-aggressive use of erythropoiesis-stimulating agents for cancer-related anemia

Echoing recent FDA warnings, a research group from Northern Ireland cautions against over-aggressive use of a group of drugs called "erythropoiesis-stimulating agents" (ESAs) to treat anemia in some cancer patients, according to a commentary in the April issue of The Oncologist, published by AlphaMed Press.

1 May 2007

Google maps used to track avian flu spread

An interactive "supermap" that portrays the mutations and spread of the avian flu around the globe over time should help researchers and policy makers better understand the virus and anticipate further outbreaks, according to a new study involving University of Colorado at Boulder and Ohio State University researchers.

1 May 2007

Estrogen fluctuation affects epileptic seizures

In more than a third of women with epilepsy, seizures fluctuate across the menstrual cycle, due in part to continually fluctuating effects of estrogen on the neural circuitry in the hippocampus, a region of the brain involved in learning and memory - and in epileptic seizures.

1 May 2007

RNA analysis can identify rejection in lung transplant patients

Recent data from the Lung Allograft Rejection Gene expression Observational (LARGO) study provides compelling evidence that profiling gene expression in peripheral blood can detect organ rejection in lung transplant patients.

1 May 2007

$Fixing running style helps lower risk for stress fractures, pain under kneecap$

Fixing running style helps lower risk for stress fractures, pain under kneecap

More than seven out of 10 runners will sustain an injury over the course of a year, many of these injuries preventable without any adverse effects on running distance or performance, according to Dr. Irene Davis, director of the Running Injury Lab at the University of Delaware, and director of Research for Drayer Physical Therapy Institute.

1 May 2007

Wall Street Journal examines ethical questions, efficacy of fertility restoration technique involving freezing ovarian tissue

A technology that allows women to have ovarian tissue removed and transplanted back into their ovaries when they want to become pregnant is becoming an "intriguing option" for women who want to delay pregnancy, the Wall Street Journal reports.

30 Apr 2007

Report on effects of extremely low frequency electric and magnetic fields on human health

A response to the Stakeholder Advisory Group's report on the effects of extremely low frequency electric and magnetic fields, by a member of SAGE.

30 Apr 2007

Human brain may be more adept at distinguishing smells than previously thought

Brains are able to adjust automatically to the demands of distinguishing between small differences in smell, new research at the University of Chicago shows.

30 Apr 2007

Chronic alcohol consumption increases tumor growth and amgiogenesis of breast cancer in female mice

For the first time, scientists have used a laboratory mouse model to mimic the development of human alcohol-induced breast cancer.

30 Apr 2007

Scientists find last unknown enzyme in the synthesis of vitamin C in plants

Vitamin C is possibly the most important small molecule whose biosynthetic pathway remained a mystery.

30 Apr 2007

Benzylpiperazine a 'new drug of abuse'

Professor Alison Jones said benzylpiperazine was a ,new drug of abuse, which could have serious clinical effects - similar to those of ecstasy to which it is structurally related.

30 Apr 2007

Green tea may help prevent bone destruction in arthritis

In rheumatoid arthritis, a person's own immune system attacks the joints by activating the synovial tissue that lines the body's movable joints, causing inflammation, swelling, pain and eventually erosion of the bone and cartilage and deformation of the joint.

30 Apr 2007