Laboratory News and Research

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Flexible interface between DNA ligase and a heterotrimeric sliding clamp supports conformational switching and efficient ligation of DNA

Scientists investigating an important DNA-repair enzyme now have a better picture of the final steps of a process that glues together, or ligates, the ends of DNA strands to restore the double helix.

20 Oct 2006

Important first step towards designing new therapies for shingles

A team of scientists at the National Institute of Allergy and Infectious Diseases (NIAID), one of the National Institutes of Health (NIH), has identified a human protein that helps varicella-zoster virus, the cause of chickenpox and shingles, spread from cell to cell within the body.

20 Oct 2006

UT Southwestern looks at promising new medication that reduces the severity and frequency of asthma attacks

UT Southwestern Medical Center is one of a handful of top research institutions evaluating a promising new medication researchers hope can reduce the severity and frequency of asthma attacks in inner-city children, a population known to have a high prevalence of severe asthma.

20 Oct 2006

Scientists discover why some bacteria are naturally magnetic

Scientists at the Naval Research Laboratory (NRL) and Purdue University have shed light on one of microbiology's most fascinating mysteries--why some bacteria are naturally magnetic.

20 Oct 2006

$74 million allocated to study environmental causes of disease

As part of the new Exposure Biology Program, the National Institute of Environmental Health Sciences, a component of the National Institutes of Health, today announced $74 million in grant opportunities for the development of new technologies that will improve the measurement of environmental exposures that contribute to human disease.

19 Oct 2006

Hospitals taking steps to limit ED patient 'boarding'

The Wall Street Journal on Wednesday examined how a "growing number of hospitals are taking steps" to limit the practice of "boarding," in which hospitals admit emergency department patients when no rooms are available and leave them in hallways for extended periods of time.

19 Oct 2006

Yellow fever and Poliomyelitis outbreaks in Africa

Yellow fever in Ivory Coast - On 5 October 2006, the Ministry of Health reported 2 cases of yellow fever in the towns of Korhogo and Ouaragahio in Ivory Coast.

19 Oct 2006

Researchers step toward therapy for respiratory syncytial virus

When a child under the age of 2 contracts a respiratory tract infection requiring hospitalization, odds are that the cause is respiratory syncytial virus (RSV).

17 Oct 2006

Parkinson's disease affects more than just motor control

Although Parkinson's disease is most commonly viewed as a "movement disorder," scientists have found that the disease also causes widespread abnormalities in touch and vision - effects that have now been verified using functional magnetic resonance imaging (fMRI) of the brain.

17 Oct 2006

Researchers identify cell line that is resistant to retroviruses

Researchers at the University of Minnesota have identified a protein that enables viruses such as HIV to infect cells and spread through the body.

17 Oct 2006

Vaccine that protects mice against 1918 influenza virus developed

Federal scientists have developed a vaccine that protects mice against the killer 1918 influenza virus. They also have created a technique for identifying antibodies that neutralize this virus, a tool that could help contain future pandemic flu strains.

17 Oct 2006

AACR announces major gift for breast cancer research

The American Association for Cancer Research today announces a $200,000 gift from the Breast Cancer Research Foundation which will create the BCRF-AACR Fund for Translational Breast Cancer Research.

17 Oct 2006

Measures to combat XDR-TB worldwide

Health experts have confirmed that the emergence of extensively drug-resistant tuberculosis (XDR-TB) poses a serious threat to public health, particularly when associated with HIV.

17 Oct 2006

Vitamin D may slow down breast cancer

The authors of a new study are suggesting that vitamin D may slow down the progression of breast cancer.

17 Oct 2006

Discovery of mechanism by which Ebola and Marburg viruses cause disease

Researchers in the Greene Infectious Disease Laboratory at Columbia University's Mailman School of Public Health, the Centers for Disease Control and Prevention, and the Caribbean Primate Research Center have discovered a key mechanism by which the Filoviruses, Ebola and Marburg, cause disease.

16 Oct 2006

DNA-based computer that could lead to faster West Nile virus detection

New technique detects signature of metastasizing melanoma with as few as 10 cancer cells present in blood sample.

16 Oct 2006

Cocaine addicts have an altered perception of reward

People addicted to cocaine have an impaired ability to perceive rewards and exercise control due to disruptions in the brain's reward and control circuits, according to a series of brain-mapping studies and neuropsychological tests conducted at the U.S. Department of Energy's Brookhaven National Laboratory.

16 Oct 2006

Ohio wild bird samples undergo additional bird flu testing

The U.S. Department of Agriculture (USDA) and Department of the Interior (DOI) has announced a detection of H5 and N1 avian influenza subtypes in samples from apparently healthy wild Northern pintails in Ottawa County, Ohio, that were killed by a hunter.

16 Oct 2006

A nanoplasmonic molecular ruler for measuring nuclease activity and DNA footprinting

The interactions between proteins and nucleic acids play a critical role in some of life’s most crucial biochemical processes, including gene expression and protein production, and some promising anticancer agents exert their effects by interfering with these interactions.

16 Oct 2006