Laboratory News and Research

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Ingredient in red peppers inhibits prostate cancer in laboratory studies

Capsaicin is the pungent ingredient in red peppers and is presently used as a topical pain reliever. Now, a new study shows it may be justified to evaluate capsaicin for inhibiting prostate cancer (CaP) in patients.

5 Apr 2006

Expert says cats may spread bird flu to humans

The rapid spread of H5N1 bird flu across Europe and the Middle East in the last month and the re-emergence of the virus in Asia, has further ignited fears that the deadly virus will mutate and cause the pandemic everyone fears.

5 Apr 2006

Adult stem cells can be used to make new tendon or ligament tissue

Weekend athletes who overexert themselves running or playing basketball may one day reap the benefits of research at the Hebrew University of Jerusalem that shows that adult stem cells can be used to make new tendon or ligament tissue.

4 Apr 2006

Custom-made bladders produced from patients' own cells

Scientists in the U.S. have produced custom-made bladders grown from patients' own cells which have been have been successfully transplanted and function well.

4 Apr 2006

Bird flu pandemic supercomputer simulation model

Using supercomputers to respond to a potential national health emergency, scientists have developed a simulation model that makes stark predictions about the possible future course of an avian influenza pandemic, given today's environment of worldwide connectivity.

4 Apr 2006

First human recipients of laboratory-grown organs

The first human recipients of laboratory-grown organs were by Anthony Atala, M.D., director of the Institute for Regenerative Medicine at Wake Forest University School of Medicine. In The Lancet, Atala describes long-term success in children and teenagers who received bladders grown from their own cells.

4 Apr 2006

New mechanism that initiates metastasis

Researchers have known for years that the enzyme MMP-9 plays a key role in the spread of colorectal cancer. Now, scientists at Jefferson Medical College in Philadelphia have found out how the enzyme helps initiate the process, known as metastasis.

4 Apr 2006

Cancer virus protein p13 needed for successful infection and reproduction

New research shows that a protein made by a cancer-causing virus that was thought to be unimportant for its replication is in fact critically needed by the virus to initiate an infection and to reproduce.

4 Apr 2006

Novel approach to creating a vaccine to treat melanoma

A novel approach to creating a vaccine to treat melanoma has demonstrated promising effectiveness in a new laboratory study led by researchers at The Wistar Institute. About a third of melanoma patients might benefit from such a vaccine.

4 Apr 2006

Researchers reverse juvenile diabetes in animal model

Groundbreaking human clinical trial for type 1 diabetes to start this spring in Pittsburgh - Children's Hospital of Pittsburgh of UPMC researchers reverse juvenile diabetes in animal model; Phase 1 clinical trial approved by FDA.

4 Apr 2006

Breakthrough in search for new anti-malarial drugs

Scientists at Drexel University College of Medicine in Philadelphia have made a significant discovery in the fight against malaria. Drexel researchers, along with a research group at the University of Washington, have determined a critical molecular structure of the cellular motor that allows the malaria parasite to invade human cells.

4 Apr 2006

Dysregulation of the Hedgehog pathway in human hepatocarcinogenesis

The unchecked activity of a cell signaling pathway crucial in embryonic development and the liver's response to injury leads to liver cancer, researchers from Duke University Medical Center and John Hopkins University School of Medicine have found.

4 Apr 2006

Robotic device appears to be more precise than conventional catheter ablation devices for atrial fibrillation

A remotely-controlled catheter device guided by magnetic fields provides a safe and practical method for delivering radio frequency ablation treatment in the hearts of patients with atrial fibrillation, according to a new study in the April 4, 2006, issue of the Journal of the American College of Cardiology.

4 Apr 2006

Skin cancer facts

Up to two-thirds of all cancers may be prevented through dietary and lifestyle changes. In the case of skin cancer, this could not be more true.

4 Apr 2006

HOXB13 and IL17BR genes predict outcome for breast cancer patients

The 2-gene expression profile of HOXB13 and IL17BR in a woman's breast cancer predicts risk of recurrence in node-negative patients treated with tamoxifen.

4 Apr 2006

Enzymes that harm brain immediately after stroke may be beneficial days later

Insights from the study could change the way stroke is treated, extending the window for effective treatment from a couple of hours to a couple of weeks. The results may suggest new ideas for drug development.

4 Apr 2006

Link between lead and osteoporosis strengthens

Bolstered by recent laboratory findings, researchers at the University of Rochester Medical Center are embarking on a National Institutes of Health-funded clinical study to better understand the deceptive role environmental lead exposure plays in bone maturation and loss.

4 Apr 2006

Responding to AIDS, TB, Malaria and emerging infectious diseases in Burma

Government policies in Burma that restrict public health and humanitarian aid have created an environment where AIDS, drug-resistant tuberculosis, malaria and bird flu (H5N1) are spreading unchecked, according to a report by researchers at the Johns Hopkins Bloomberg School of Public Health.

4 Apr 2006

Mesenchymal multipotency of adult human periosteal cells demonstrated by single-cell lineage analysis

Inflammation, cartilage and bone erosions, joint destruction--that's the typical progression of arthritis and most rheumatic diseases.

4 Apr 2006

Transportation of prion protein across the intestinal mucosa of scrapie-susceptible and scrapie-resistant sheep

While newly published research confirms that under laboratory circumstances prion-protein can be absorbed across the gut, it also shows that this is unlikely to occur in real life.

4 Apr 2006