Laboratory Techniques News and Research

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New technique allows production of medically useful amounts of endoderm cells from human PSCs

Scientists in Canada have overcome a key research hurdle to developing regenerative treatments for diabetes and liver disease with a technique to produce medically useful amounts of endoderm cells from human pluripotent stem cells. The research, published in Biotechnology and Bioengineering, can be transferred to other areas of stem cell research helping scientists to navigate the route to clinical use known as the 'valley of death'.

3 Dec 2011

Tailored anti-platelet therapy optimizes treatment for patients wtih common genetic variant

Tailored anti-platelet therapy, made possible through a novel point-of-care genetic test, optimizes treatment for patients who carry a common genetic variant, researchers at the University of Ottawa Heart Institute (UOHI) have found.

10 Nov 2011

Researchers identify surprising mechanism that facilitates protein interactions

Research led by St. Jude Children's Research Hospital scientists has identified an unexpected mechanism facilitating some protein interactions that are the workhorses of cells and, in the process, identified a potential new cancer drug development target.

5 Nov 2011

Recycling protein molecules could lead to new therapies for Alzheimer's disease

The formation of abnormal strands of protein called amyloid fibrils - associated with two dozen diseases ranging from Alzheimer's to type-2 diabetes - may not be permanent and irreversible as previously thought, scientists are reporting in the Journal of the American Chemical Society.

26 May 2011

New discovery on IL-23 can lead to novel IBD treatments

A new discovery published in the April 2001 issue of Journal of Leukocyte Biology raises hope that new treatments for illnesses like Crohn's disease and ulcerative colitis are on the horizon.

1 Apr 2011

Renishaw launches first RUO multiplex assay system

Renishaw Diagnostics Ltd, a world leading provider of trace level detection technologies based on the exploitation of surface enhanced Raman scattering and surface enhanced resonance Raman scattering, for research and molecular diagnostics applications, today announced the launch of its first research use only multiplex assay system which allows precious research samples to be 'screened' for 10 or more 'targets', from a single sample.

1 Mar 2011

Oral sex linked to cancer

Researchers from the United States have said that there is strong evidence linking oral sex to cancer. They have urged more study of how human papillomaviruses may be to blame for a rise in oral cancer among white men.

20 Feb 2011

Rotator cuff surgery does not fully restore normal shoulder motion, strength: Study

Shoulder motion after rotator cuff surgery remains significantly different when compared to the patient's opposite shoulder, according to a Henry Ford Hospital study.

18 Jan 2011

Cold Spring Harbor Protocols features standard and cutting-edge imaging laboratory techniques

Imaging has rapidly become a defining tool of the current era in biological research. But finding the right method and optimizing it for data collection can be a daunting process, even for an established imaging laboratory. Cold Spring Harbor Protocols is one of the world's leading sources for detailed technical instruction for implementation of imaging methods, and the November issue features articles detailing standard and cutting-edge laboratory techniques.

2 Nov 2010

Cardialysis and Sticares InterACT announce strategic collaboration

Cardialysis and Sticares InterACT, both Contract Research Organizations (CROs) headquartered in The Netherlands, announced today that they have entered into a strategic collaboration to provide drug development consulting services in the field of cardiovascular and metabolic medicine. Both organizations have substantial experience and success in the execution of clinical research projects for pharmaceutical, biotechnology and medical device companies.

23 Sep 2010

Neutralizing inhibitory molecules does not improve regeneration in damaged spinal axons

Neuroscientists at the University of California, San Diego School of Medicine have found that removing three key inhibitory molecules from myelin - the insulating material that surrounds nerve cell fibers - does not significantly boost the ability of injured spinal axons to regenerate and restore themselves to full function.

10 Jun 2010

MU researchers determine efficient method for assessing body composition

Measuring body composition - the amount of fatty tissue, muscle tissue and bone present in the body - can provide valuable information for determining an individual's overall health status. However, obtaining accurate measurements can be difficult and expensive, according to Steve Ball, University of Missouri Extension fitness specialist.

17 Apr 2010

Shoulder motion after rotator cuff surgery remains different: Study

Shoulder motion after rotator cuff surgery remains significantly different when compared to the patient's opposite shoulder, according to Henry Ford Hospital researchers.

8 Mar 2010

Plants too can make progesterone

In a finding that overturns conventional wisdom, scientists are reporting the first discovery of the female sex hormone progesterone in a plant. Until now, scientists thought that only animals could make progesterone. A steroid hormone secreted by the ovaries, progesterone prepares the uterus for pregnancy and maintains pregnancy. A synthetic version, progestin, is used in birth control pills and other medications. The discovery is reported in the American Chemical Society's Journal of Natural Products, a monthly publication.

5 Feb 2010

FDA opens third city post in Latin America

As part of its continuing effort to buttress food and medical product safety in this country by working with its regulatory partners overseas, the U.S. Food and Drug Administration today announced the opening of its Mexico City post. This is the Agency's third post in Latin America and its tenth international post in the past 13 months.

15 Dec 2009

Ahura Scientific reaches two milestones: Achieves $100 million in revenues and serves 100 pharmaceutical facilities

Ahura Scientific, Inc., the leader in field-deployed analytical instruments for human health and public safety, today announced two milestones: it has reached $100 million in product revenue since its first product shipment in 2005 and the company now serves more than 100 pharmaceutical facilities within two years of introducing its TruScan device to the market.

17 Sep 2009

Nanofluidic biopsy detects subtle changes in cancer cells

By taking two standard laboratory techniques - capillary electrophoresis and antibody-based protein detection - and shrinking them to the nanoscale, researchers at the Stanford University School of Medicine have created a new method for detecting miniscule changes in the levels of proteins associated with cancer.

28 Jun 2009

Discovery of genetic cause of luminal-type tumors

The discovery of tumor-suppressor genes has been key to unlocking the molecular and cellular mechanisms leading to uncontrolled cell proliferation - the hallmark of cancer. Often, these genes will work in concert with others in a complex biochemical system that keeps our cells growing and dividing, disease free.

12 May 2009

B-cell clones as early markers for chronic lymphocytic leukemia

Testing of blood specimens may detect abnormal white blood cells in patients years before the chronic form of lymphocytic leukemia (CLL) develops, according to research published in the current issue of the New England Journal of Medicine.

22 Feb 2009

Researchers create precise biosensor for detecting blood glucose

Researchers have created a precise biosensor for detecting blood glucose and potentially many other biological molecules by using hollow structures called single-wall carbon nanotubes anchored to gold-coated "nanocubes."

23 Jan 2009