Lipoprotein News and Research

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A lipoprotein is a biochemical assembly that contains both proteins and lipids. The lipids or their derivatives may be covalently or non-covalently bound to the proteins.

Designer RNA fights high cholesterol, medical researchers find

Small, specially designed bits of ribonucleic acid (RNA) can interfere with cholesterol metabolism, reducing harmful cholesterol by two-thirds in pre-clinical tests, according to a new study by researchers at UT Southwestern Medical Center in collaboration with Alnylam Pharmaceuticals and the Massachusetts Institute of Technology.

11 Aug 2008

Newly identified risk factor for cardiovascular disease may lead to new treatments

Low levels of naturally occurring antibodies may represent an increased risk of developing cardiovascular disease, particularly stroke in men. This discovery, published in the academic journal Atherosclerosis, has now led to attempts to develop an immunization against cardiovascular disease.

31 Jul 2008

More research needed into effects of flavonoids and flavonoid-rich food sources on heart disease

More research is needed into food compounds which could reduce the risk of heart disease, according to a systematic review of trials carried out so far.

10 Jul 2008

Combining medical knowledge to save lives

Cardiovascular disease (CVD) is the biggest killer among chronic diseases, claiming 17 million lives globally every year. Yet doctors can only attribute 50% of cardiovascular diseases to known risk factors.

9 Jul 2008

Low levels of good cholesterol could signal dementia

A study by British and French scientists has revealed that the risk of dementia may increase with a lack of "good" cholesterol in middle age.

1 Jul 2008

Low levels of high-density lipoproteins linked to memory loss, dementia risk

Low levels of high-density lipoproteins (HDL) - the "good" cholesterol - in middle age may increase the risk of memory loss and lead to dementia later in life, researchers reported in Arteriosclerosis, Thrombosis and Vascular Biology: Journal of the American Heart Association.

30 Jun 2008

Fatty liver disease may raise heart disease risk in overweight, obese kids

A fatty liver disease that is not well-known in overweight and obese children may be a precursor of cardiovascular disease, researchers reported in Circulation: Journal of the American Heart Association.

30 Jun 2008

Low levels of vitamin D in men linked to heart attack

Low levels of vitamin D appear to be associated with higher risk of myocardial infarction (heart attack) in men, according to a report in the June 9 issue of Archives of Internal Medicine.

9 Jun 2008

Gene discovery could help answer basic questions of upright walking

What are the genes implicated in upright walking of humans? The discovery of four families in which some members only walk on all fours (quadrupedality) may help us understand how humans, unlike other primates, are able to walk for long periods on only two legs, a scientist will tell the annual conference of the European Society of Human Genetics tomorrow (Monday 2 June).

1 Jun 2008

Blood cholesterol levels predict risk of heart disease due to hormone therapy

A new analysis of a subgroup of participants in the Women's Health Initiative (WHI) hormone therapy clinical trials suggests that healthy, postmenopausal women whose blood cholesterol levels are normal or lower are not at increased, short-term risk for heart attack when taking hormone therapy.

26 May 2008

Discovery of potential target for elevated triglycerides

Diabetes researchers at the John G. Rangos Sr. Research Center at Children's Hospital of Pittsburgh of UPMC have identified a potential target for the development of new therapies to treat hypertriglyceridemia, a lipid disorder commonly seen in people who are obese and diabetic. Results of their study are published in the June issue of the Journal of Clinical Investigation.

26 May 2008

New blood test reveals risk for metabolic syndrome

University of Minnesota researchers have discovered that people with high oxidation levels of the low-density lipoprotein (LDL) particle that carries cholesterol throughout the blood are much more likely to develop metabolic syndrome - which can lead to a considerably increased risk of developing heart disease.

20 May 2008

Erection problems may signal serious heart disease

Erectile dysfunction is always a matter of the heart, but new research shows that more than romance is at stake. Two new studies of men with type 2 diabetes found that erectile dysfunction (ED) was a powerful early warning sign for serious heart disease, including heart attack and death.

19 May 2008

Pediatric obesity program effectively improves outcomes for kids

A multidisciplinary pediatric weight management program can improve the weight status of high-risk patients, according to Joseph Skelton, M.D., a pediatric gastroenterologist and Director of the Pediatric Weight Management program (called Brenner FIT) at Brenner Children's Hospital.

15 May 2008

Atherotech VAP cholesterol test meets updated ADA, ACC measurement and treatment guidelines for high risk patients

The determination of LDL, non-HDL and apoB are now recognized as valid, accurate and recommended methods of guiding and achieving the best treatment goals for patients with cardiometabolic risk (CMR).

22 Apr 2008

Developmental changes during the teenage years raise men's heart disease risk

Normal developmental changes during the teenage years leave young adult men at higher risk of heart disease than their female counterparts, researchers report in Circulation: Journal of the American Heart Association.

21 Apr 2008

Experimental study on most common form of heart valve disease in Western countries may lead to new treatments

A team of scientists from the University of Montreal and the Montreal Heart Institute Research Centre, led by Dr. Jean-Claude Tardif, has completed an important study that show how a new type of medication can lead to an improvement in the aortic valve narrowing

18 Apr 2008

DASH diet also may cut risk for heart disease, stroke

Women who eat diets similar to the Dietary Approaches to Stop Hypertension (DASH) diet -which is low in animal protein, moderate in low-fat dairy products and high in plant proteins, fruits and vegetables - appear to have a lower risk of coronary heart disease and stroke, according to a report in the April 14 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

15 Apr 2008

Statins may help control blood pressure

Researchers in the States say that statins, the popular cholesterol-lowering drugs, may also lower blood pressure.

15 Apr 2008

Macadamia nuts decrease risk of heart disease

Macadamia nuts included in a heart healthy diet reduced low-density cholesterol (bad cholesterol) and should be included among nuts with qualified health claims, according to researchers.

13 Apr 2008