Mass Spectrometry News and Research

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Mass spectrometry is an analytical method used to identify different compounds based on the atomic sample constitution of the molecules and their charge state, which enables “blind” analysis of an unknown sample without any prior knowledge of its composition.

Neoantigen discovery sheds light on cancer immunogenicity

Researchers reported a proteogenomic approach to investigate fresh solid melanoma tumor material.

4 Aug 2023

Study highlights metabolite targets for depression prevention that are easily modifiable through diet interventions

Researchers used a UHPLC and mass spectrometry-based Metabolon platform to identify and characterize circulating metabolites associated with depression.

1 Aug 2023

Study illuminates new connections between diet and immunity

A metabolic by-product that is more prevalent during fasting may supercharge immune cells as they fight infection and disease, reports an early stage study by Van Andel Institute scientists and collaborators.

28 Jul 2023

Breakthrough stress sensor discovery reveals new mechanism of antimicrobial resistance

Researchers from the Antimicrobial Resistance (AMR) Interdisciplinary Research Group (IRG) at Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, in collaboration with Singapore Centre for Environmental Life Sciences Engineering (SCELSE), Nanyang Technological University Singapore (NTU Singapore) and Massachusetts Institute of Technology (MIT), have discovered a new stress signaling system that enables bacteria cells to adapt and protect themselves against the immune system and certain antibiotics.

24 Jul 2023

KIPA shows promise in predicting chemotherapy response in triple negative breast cancer

Researchers at Baylor College of Medicine and collaborating institutions are developing a strategy to predict the response of triple negative breast cancer (TNBC) to chemotherapy, which would be a valuable tool for physicians deciding on the treatment with better probability of success on an individual basis.

21 Jul 2023

Using single-cell mass spectrometry to study antimicrobial treatment failure

Laura-Isobel McCall, Ph.D., and Zhibo Yang, Ph.D., co-principal investigators and associate professors of chemistry and biochemistry in the Dodge Family College of Arts and Sciences at the University of Oklahoma, have been awarded a prestigious R01 grant from the National Institutes of Health for their project, "Novel single-cell mass spectrometry to assess the role of intracellular drug concentration and metabolism in antimicrobial treatment failure."

19 Jul 2023

Researchers convert β-Pinene into renewable feedstock for sustainable paracetamol and ibuprofen

Researchers have developed scalable processes to convert β-pinene into 4-IPEC, a feedstock for synthesizing sustainable versions of paracetamol and ibuprofen.

19 Jul 2023

Study reveals potential target for repairing beta-cell dysfunction in Type 2 diabetes

Researchers used a murine model to demonstrate that functional excision of murine PITPNA eventually led to hyperglycemia in mice.

19 Jul 2023

AI and infection control: preventing infectious disease outbreaks and pandemics

Researchers discussed the role of artificial intelligence (AI) in preventing outbreaks of infectious diseases and future pandemics.

19 Jul 2023

Study identifies blood proteins linked to mortality in severe burns

Researchers led by Osaka University have used mass spectrometry to identify ten blood proteins associated with mortality in severe burns.

18 Jul 2023

Iodine content in retail cow’s milk varies dramatically across the U.S.

Researchers investigate the amounts of iodine in retail cow’s milk across the United States.

13 Jul 2023

Long-term high fluoride exposure during adolescence causes hippocampal impairments

Researchers evaluated the impacts of prolonged fluoride exposure during adolescence and adulthood on cognition and associated hippocampal alterations.

13 Jul 2023

Australian rainforest remedies: Scientists explore bioactive plant compounds as potential anti-neuroinflammatory agents

Research discusses the process of discovering anti-inflammatory and neuroprotective drugs from medicinal plants found in the Australian rainforest. It focuses on the pathways from the discovery of bioactive plants to the validation in an appropriate neuro-inflammatory mouse model, using some examples from their current research.

9 Jul 2023

Study uncovers three previously unknown membrane proteins in ovarian cancer

A study led by Nagoya University in Japan has identified three previously unknown membrane proteins in ovarian cancer.

7 Jul 2023

Novel workflow reveals untapped diversity in fatty acid isomers across all life forms

Researchers introduced a comprehensive workflow to discover unsaturated fatty acids (FA).

6 Jul 2023

Scientists identify blood proteins that may predict Type 1 diabetes

Scientists have taken an important step forward in predicting who will develop Type 1 diabetes months before symptoms appear.

4 Jul 2023

Cutting-edge research: machine learning identifies early predictors of type 1 diabetes

Scientists utilized plasma protein proteomics to identify proteins associated with the onset of type 1 diabetes.

3 Jul 2023

Combining proteomic and miRNA data yields superior age predictions, study suggests

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 12, entitled, "Age prediction from human blood plasma using proteomic and small RNA data: a comparative analysis."

30 Jun 2023

New method can track the complete activity of proteins in living cells

The genetic plans within our DNA come to functional fruition through proteins, which underlie our bodies' structure and activity.

29 Jun 2023

Microbial exposure during infancy contributes immune system development

The research paper explores the role of early life environmental factors and the human microbiome in the development of atopy and asthma. It highlights the potential impact of exposures on immune function and provides insights into microbial mediators of chronic inflammatory diseases in childhood.

29 Jun 2023

Mass Spectrometry News and Research

Further Reading

Neoantigen discovery sheds light on cancer immunogenicity

Study highlights metabolite targets for depression prevention that are easily modifiable through diet interventions

Study illuminates new connections between diet and immunity

Breakthrough stress sensor discovery reveals new mechanism of antimicrobial resistance

KIPA shows promise in predicting chemotherapy response in triple negative breast cancer

Using single-cell mass spectrometry to study antimicrobial treatment failure

Researchers convert β-Pinene into renewable feedstock for sustainable paracetamol and ibuprofen

Study reveals potential target for repairing beta-cell dysfunction in Type 2 diabetes

AI and infection control: preventing infectious disease outbreaks and pandemics

Study identifies blood proteins linked to mortality in severe burns

Iodine content in retail cow’s milk varies dramatically across the U.S.

Long-term high fluoride exposure during adolescence causes hippocampal impairments

Australian rainforest remedies: Scientists explore bioactive plant compounds as potential anti-neuroinflammatory agents

Study uncovers three previously unknown membrane proteins in ovarian cancer

Novel workflow reveals untapped diversity in fatty acid isomers across all life forms

Scientists identify blood proteins that may predict Type 1 diabetes

Cutting-edge research: machine learning identifies early predictors of type 1 diabetes

Combining proteomic and miRNA data yields superior age predictions, study suggests

New method can track the complete activity of proteins in living cells

Microbial exposure during infancy contributes immune system development

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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