Mass Spectrometry News and Research

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Mass spectrometry is an analytical method used to identify different compounds based on the atomic sample constitution of the molecules and their charge state, which enables “blind” analysis of an unknown sample without any prior knowledge of its composition.

Recipients of 2015 AACC and NACB Awards announced

AACC and its academy, the National Academy of Clinical Biochemistry, are pleased to announce the recipients of the 2015 AACC and NACB Awards, which honor laboratory medicine professionals worldwide for advancing the field of clinical laboratory testing.

14 Feb 2015

Study: Iodine deficiency during pregnancy can impair child's intellectual development

Pregnant women in Austria commonly suffer from an iodine deficiency. This may have a negative impact on the development of their unborn child's brain. These are the key findings of a joint study by the Endocrinology and Metabolism Unit at the University Department of Internal Medicine III together with the University Department of Gynaecology at the MedUni Vienna and AGES, which have now been published in the European Journal of Clinical Nutrition.

20 Jan 2015

Study leads to discovery of rare genetic disorder

Recently, a grassroots effort initiated by families and clinicians led to the discovery of a human genetic disorder with severe consequences that is linked to a mutation in the human NGLY1 gene. In a big step towards understanding the effects of this mutation, research by scientists at the RIKEN-Max Planck Joint Research Center in Japan implicates the enzyme ENGase as the factor responsible for deficient protein degradation that occurs in the absence of mouse Ngly1 gene expression.

19 Jan 2015

Iron accumulation in human tissues may contribute to the aging process

It's been known for decades that some metals, including iron, accumulate in human tissues during aging and that toxic levels of iron have been linked to neurologic diseases, such as Parkinson's. Common belief has held that iron accumulation happens as a result of the aging process.

17 Jan 2015

CNIO researchers identify new mechanism that influences differentiation of keratinocytes

The formation of human skin involves a cascade of biochemical signals, which are not well understood. However, they are very important since their failure may cause diseases, such as Atopic Dermatitis and skin cancers, which affect more than 25% of the human population.

16 Jan 2015

Preventing gas chromatography (GC) leaks

Leaks at gas chromatography (GC) column connections are a common source of frustration and wasted time in laboratories. Time is often spent manually tightening connections between columns using a handheld tool – time which could otherwise be spent analyzing results or running more investigations. Preventing GC leaks has become a priority for researchers looking to save time and money while achieving high quality results.

From Agilent Technologies - Mass Spectrometry 23 Dec 2014

Researchers map B cell response to non-gluten proteins of wheat in celiac disease

Researchers at Columbia University Medical Center have found that, in addition to gluten, the immune systems of patients with celiac disease react to specific types of non-gluten protein in wheat. The results were reported online in the Journal of Proteome Research.

16 Dec 2014

Researchers develop new method to track movement of carcinogenic PAHs in the human body

Researchers for the first time have developed a method to track through the human body the movement of polycyclic aromatic hydrocarbons, or PAHs, as extraordinarily tiny amounts of these potential carcinogens are biologically processed and eliminated.

11 Dec 2014

Real-time surgical guidance study to evaluate TriVersa NanoMate with LESA capability from Advion

Advion, Inc. announces that is its TriVersa NanoMate with liquid extraction surface analysis (LESA) capability will be evaluated as part of a study at Brigham and Women’s Hospital.

From Advion 2 Dec 2014

Antibiotic for infections comes from good bacteria found in turkeys

While the turkey you eat on Thursday will bring your stomach happiness and could probably kick-start an afternoon nap, it may also save your life one day.

26 Nov 2014

Quadrupole time-of-flight mass spectrometry for life science research analysis announced by Bruker

Bruker Corporation (NASDAQ: BRKR) announced today, the evolution of their maXis™ line of ultrahigh-resolution quadrupole time-of-flight (UHR-qTOF) mass spectrometers, bringing industry-leading resolution and mass accuracy to the liquid chromatography, time-of-flight MS market space.

From Bruker 6 Nov 2014

Scientists identify potent inhibitors to combat common obesity gene

Individuals who are genetically predisposed to obesity may soon have a therapeutic solution to combat their condition. A research team led by scientists from the National University of Singapore (NUS) has identified several potent inhibitors that selectively target FTO, the common fat mass and obesity-associated gene.

21 Oct 2014

Identifying infections rapidly: an interview with Dr. David J. Ecker

Current methods for diagnosing infectious diseases are based on the 150-year-old culture method, where physicians collect a sample of a patient’s tissue, such as blood, mucus or urine, and transfer it onto media bottle to allow the pathogens to grow.

From Abbott Diagnostics 20 Oct 2014

Proteins linked to severe forms of ALS are less stable, suggests new study

A new study by scientists from The Scripps Research Institute, Lawrence Berkeley National Laboratory and other institutions suggests a cause of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease.

14 Oct 2014

BIDMC scientists uncover new class of molecules that protects against diabetes

Scientists at the Salk Institute and Beth Israel Deaconess Medical Center in Boston have discovered a new class of molecules—produced in human and mouse fat—that protects against diabetes.

10 Oct 2014

Slug flow microextraction method for drug testing yields results in one minute

A new technique makes it possible to quickly detect the presence of drugs or to monitor certain medical conditions using only a single drop of blood or urine, representing a potential tool for clinicians and law enforcement.

10 Oct 2014

Discovery offers promising new avenue for prevention, treatment of type 2 diabetes

The surprising discovery of a previously unidentified class of lipid molecules that enhance insulin sensitivity and blood sugar control offers a promising new avenue for the prevention and treatment of type 2 diabetes.

10 Oct 2014

Exclusive partnership brings together next-generation proteomics and next-generation sequencing

AB SCIEX and Illumina (NASDAQ: ILMN) announced today the OneOmics™ project, an exclusive partnership to bring together SWATH™-based next-generation proteomics (NGP) and next-generation sequencing (NGS) tools in a cloud computing environment.

3 Oct 2014

Imperial scientists map proteins affected by NMT enzyme, suggest potential way to treat cancer

Imperial chemists have gained fresh insights into how a disease-causing enzyme makes changes to proteins and how it can be stopped.

26 Sep 2014

Pitt researchers awarded new $5.8 million NIH grant to develop microfluidic 3D liver model system

With a new $5.8 million, three-year award from the National Institutes of Health, researchers at the University of Pittsburgh School of Medicine will further develop a state-of-the-art, microfluidic 3D model system that mimics structure and function of the liver to better predict organ physiology, assess drug toxicity and build disease models.

25 Sep 2014

Mass Spectrometry News and Research

Further Reading

Recipients of 2015 AACC and NACB Awards announced

Study: Iodine deficiency during pregnancy can impair child's intellectual development

Study leads to discovery of rare genetic disorder

Iron accumulation in human tissues may contribute to the aging process

CNIO researchers identify new mechanism that influences differentiation of keratinocytes

Preventing gas chromatography (GC) leaks

Researchers map B cell response to non-gluten proteins of wheat in celiac disease

Researchers develop new method to track movement of carcinogenic PAHs in the human body

Real-time surgical guidance study to evaluate TriVersa NanoMate with LESA capability from Advion

Antibiotic for infections comes from good bacteria found in turkeys

Quadrupole time-of-flight mass spectrometry for life science research analysis announced by Bruker

Scientists identify potent inhibitors to combat common obesity gene

Identifying infections rapidly: an interview with Dr. David J. Ecker

Proteins linked to severe forms of ALS are less stable, suggests new study

BIDMC scientists uncover new class of molecules that protects against diabetes

Slug flow microextraction method for drug testing yields results in one minute

Discovery offers promising new avenue for prevention, treatment of type 2 diabetes

Exclusive partnership brings together next-generation proteomics and next-generation sequencing

Imperial scientists map proteins affected by NMT enzyme, suggest potential way to treat cancer

Pitt researchers awarded new $5.8 million NIH grant to develop microfluidic 3D liver model system

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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