Mass Spectrometry News and Research

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Mass spectrometry is an analytical method used to identify different compounds based on the atomic sample constitution of the molecules and their charge state, which enables “blind” analysis of an unknown sample without any prior knowledge of its composition.

Researchers use new tools to measure and track B-12 vitamins in the ocean

The phrase, 'Eat your vitamins,' applies to marine animals just like humans. Many vitamins, including B-12, are elusive in the ocean environment.

25 Feb 2014

Fluidigm acquires DVS Sciences

Fluidigm Corp. today announced it has completed its acquisition of DVS Sciences, Inc. With the closing of the acquisition, Fluidigm adds a high-parameter single-cell protein analysis platform to its industry-leading single-cell genomics platforms to create a comprehensive portfolio of advanced technologies serving the rapidly growing single-cell genomics and proteomics markets.

13 Feb 2014

Odor-producing chemicals in earwax differ according to ethnic origin

Scientists from the Monell Center have used analytical organic chemistry to identify the presence of odor-producing chemical compounds in human earwax. Further, they found that the amounts of these compounds differ between individuals of East Asian origin and Caucasians.

13 Feb 2014

Scientists identify twenty proteins specifically secreted by primary effusion lymphoma cell lines

Primary effusion lymphoma (PEL) is a rare B-cell neoplasm distinguished by its tendency to spread along the thin serous membranes that line body cavities without infiltrating or destroying nearby tissue.

10 Feb 2014

Scientists reveal important degradation pathway of sulpho-glucose

By discovering sulpho-glycolysis, researchers of the University of Konstanz reveal an important degradation pathway.

5 Feb 2014

Llama-derived antibodies open door to development of new treatments for C. difficile infections

Researchers from the Alberta Glycomics Centre at the University of Calgary and the University of Alberta, in collaboration with researchers at the National Research Council of Canada in Ottawa, have revealed the first molecular views showing how highly specific antibodies derived from llamas may provide a new method for controlling deadly infections from the opportunistic bacterial pathogen Clostridium difficile (C. difficile).

31 Jan 2014

Thermo Fisher Scientific fourth quarter revenue increases 6% to $3.47 billion

Thermo Fisher Scientific Inc., the world leader in serving science, today reported its financial results for the fourth quarter and full year ended December 31, 2013.

30 Jan 2014

CU receives cooperative agreement to develop technological system to determine effects chemical agents

The University of Colorado Boulder has been awarded a cooperative agreement worth up to $14.6 million from the Defense Advanced Research Projects Agency (DARPA) to develop a new technological system to rapidly determine how drugs and biological or chemical agents exert their effects on human cells.

29 Jan 2014

New halal testing method for detecting pig and horse contamination of meat

The mislabeling of meat products sold for human consumption has serious implications from a safety and ethical perspective. With recent news stories of pork and horsemeat contamination in different parts of the world, a renewed need for specialized testing of the food supply has rapidly arisen.

28 Jan 2014

Researchers discover mechanism that controls activity of LRRK2 in Parkinson's disease

In one variant of Parkinson's disease, the enzyme LRRK2 plays a central role. Scientists at the University of Kassel have now discovered a mechanism that controls the activity of LRRK2.

24 Jan 2014

University of Huddersfield scientist awarded prestigious Clulow Award by British Pain Society

IN the UK alone, an estimated 7.8 million people have their lives blighted by chronic pain, and 44 per cent are failing to receive an accurate diagnosis and appropriate treatment. Now, a University of Huddersfield scientist, backed by funding from the British Pain Society and crucial support from the National Institute of Health Research, is embarking on research which aims to help doctors diagnose and treat one of the least understood but most widespread sources of chronic suffering.

18 Jan 2014

Scientists develop strategies focused on diet to treat patients suffering from circadian dysfunctions

Living organisms have adapted to the day-night cycle and, in most cases, they have evolved a "circadian clock". Its effects are not completely known yet but its functioning has been shown to have important metabolic consequences for the body.

16 Jan 2014

New study examines factors that may lead to end stage renal disease

About 33 percent of people with type 2 diabetes suffer kidney damage that progresses to end stage renal disease, at which point they require either dialysis or kidney transplantation. Scientists have thought that this kidney disease is driven by damage to the glomeruli, blood vessels in the kidney, which spill the protein albumin into the urine. Current treatments targeting the resulting "albuminuria" do not prevent kidney failure.

15 Jan 2014

Plasma thermogram can serve as an indicator of cervical cancer

Researchers at the University of Louisville have confirmed that using the heat profile from a person's blood, called a plasma thermogram, can serve as an indicator for the presence or absence of cervical cancer, including the stage of cancer.

8 Jan 2014

Researchers explore treatment targets for hypobaric hypoxia brain injury

Hypobaric hypoxia can cause severe brain damage and mitochondrial dysfunction, and is involved in hypoxic brain injury. Dr. Jianyu Li and colleagues from Logistics College of Chinese People's Armed Police Forces evaluated the degree of brain damage with different exposure times to hypoxia and further investigate the differential expression of cerebral mitochondrial proteins by comparative proteomic analysis, in a broader attempt to search for treatment targets of hypobaric hypoxia brain injury.

6 Jan 2014

Scientists obtain detailed molecular structure of member of Tet family of enzymes

Scientists have obtained the first detailed molecular structure of a member of the Tet family of enzymes.

28 Dec 2013

International researchers study glycans that could help clinicians diagnose gastric cancer early

Gastric cancer kills more than 700,000 people each year, mostly in Latin America, Asia and Eastern Europe. Though the disease is quite treatable when caught early, symptoms are indistinct and late detection leads to high mortality. The five-year survival rate in the United States is 26.9 percent.

22 Dec 2013

Two GW professors named 2013 Fellows of the National Academy of Inventors

Ferid Murad and Akos Vertes-two of George Washington University's scientific pioneers-are among the 143 innovators who have been named 2013 Fellows of the National Academy of Inventors.

19 Dec 2013

Mitochondrial enzyme SIRT5 regulates proteins involved in metabolism

The Sirtuin family of protein deacylases has received considerable attention in recent years due to its links to longevity, diabetes, cancer, and metabolic regulation.

12 Dec 2013

Scientists target protein-detection approach to systematically measure human repertoire of proteins

An international team of scientists led by Fred Hutchinson Cancer Research Center cancer proteomics expert Amanda Paulovich, M.D., has demonstrated the feasibility of large-scale, standardized protein measurements, which are necessary for validation of disease biomarkers and drug targets.

9 Dec 2013