Mechanobiology News and Research

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Researchers uncover cellular-level detail of what happens when bone bears stress over time

From athletes to individuals suffering from osteoporosis, bone fractures are usually the result of tiny cracks accumulating over time -- invisible rivulets of damage that, when coalesced, lead to that painful break.

8 Mar 2013

Two National University of Singapore scientists win Lasker Awards for medical research

Two scientists from the National University of Singapore (NUS) - Professor Michael Sheetz, Director of the Mechanobiology Institute of Singapore; and Professor Roy Calne, Visiting Professor with the NUS Yong Loo Lin School of Medicine's Department of Surgery - have been conferred the prestigious Lasker Awards for making great advances in medical research.

11 Sep 2012

Study illuminates key step in the journey of inflammation-producing immune cells

Like detectives seeking footprints and other clues on a television "whodunit," science can also benefit from analyzing the tracks of important players in the body's molecular landscape. Klaus Ley, M.D., a scientist at the La Jolla Institute for Allergy & Immunology, has done just that and illuminated a key step in the journey of inflammation-producing immune cells.

2 Jul 2012

Study shows how a drug-lead compound suppresses tumour formation

A team of scientists from the National University of Singapore's (NUS) Department of Biological Sciences and Mechanobiology Institute have discovered how a drug-led compound - a compound that is undergoing preclinical trials as a potential drug - can deprive cancer cells of energy and stop them from growing into a tumour. This drug-led compound is named BPTES.

21 May 2012

New system could measure mechanical properties of living cells

Researchers are making progress in developing a system that measures the mechanical properties of living cells, a technology that could be used to diagnose human disease and better understand biological processes.

22 Nov 2011

Scientists discover technique for more controlled lab experiments on cellular mechanobiology

Bioengineers at the University of Pennsylvania have created a system to control the flexibility of the substrate surfaces on which cells are grown without changing the surface properties, providing a technique for more controlled lab experiments on cellular mechanobiology, an important step in the scientific effort to understand how cells sense and respond to mechanical forces in their environment.

2 Aug 2010

NRF and MOE fund support for SCELSE microbial biofilm research centre

The National Research Foundation (NRF) and the Ministry of Education (MOE) announced today the funding support for a Research Centre of Excellence (RCE) called the Singapore Centre on Environmental Life Sciences Engineering (SCELSE) to be set up at the Nanyang Technological University (NTU).

15 Feb 2010

Scientists discover new protein function that helps control cell behavior

Carnegie Mellon University's Philip R. LeDuc and his collaborators in Massachusetts and Taiwan have discovered a new function of a protein that could ultimately unlock the mystery of how these workhorses of the body play a central role in the mechanics of biological processes in people.

13 Jan 2010

$1.3 million fund awarded to WPI for ongoing life sciences research

Researchers at Worcester Polytechnic Institute's (WPI) Life Sciences and Bioengineering Center at Gateway Park have received a total of $1.3 million in new awards from the National Institutes of Health (NIH) and the National Science Foundation (NSF) to fund ongoing research in several areas of the life sciences, including a study of the bacterium that causes tuberculosis, work aimed at using adult stem cells to repair damaged hearts, and a project that seeks to create engineered blood vessels.

28 Sep 2009