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In vitro fertilisation could be causing genetic errors in embryo

The conditions in which embryos are cultured in the laboratory during in vitro fertilisation could be causing genetic errors that are associated with certain developmental syndromes and other abnormalities in growth and development, such as low birth weight.

19 Jun 2006

New method of testing eggs for abnormalities could solve problems of embryo freezing

Italian researchers have shown for the first time that it is possible to test a woman's egg, before fertilisation, for chromosomal abnormalities that might make an embryo less likely to implant successfully or more likely to miscarry at a later stage.

19 Jun 2006

Scientists cracking virus protection shield

Scientists reveal the structure of a protein that packages the viral genome and helps viruses to replicate while avoiding human immune reactions

18 Jun 2006

Discovery of gene behind iron accumulation in brain has implications for Parkinson's, Alzheimer's

Oregon Health & Science University researchers have identified the gene behind a group of rare, progressive childhood disorders caused by an abnormal buildup of iron in the brain.

18 Jun 2006

Parkinson's patients stomach new drug better than conventional meds

Several studies conducted at Baylor College of Medicine (BCM) in Houston show that a new kind of orally disintegrating tablets provides improved symptom relief for patients with Parkinson's disease.

13 Jun 2006

Research explains how pathogenic bacteria evolved over millions of years

Bacteria like Salmonella have a complicated immune system that helps them recognize and isolate foreign DNA trying to invade their cell membrane, according to a University of Washington-led study in the June 8 issue of Science Express.

9 Jun 2006

The antimicrobial peptide cathelicidin protects the urinary tract against invasive bacterial infection

Researchers at Karolinska Institutet in Sweden have succeeded in explaining how the body protects itself against urinary tract infections; with the help of an endogenous antibiotic.

9 Jun 2006

Protein called Elk-1appears to play role in neurodegeneration and schizophrenia

Pprotein called Elk-1 interacts with mitochondria, the energy storehouse of a cell, suggesting that this protein - typically active in the nucleus - could play a role in cell death and mitochondria-related diseases such as neurodegeneration and schizophrenia.

9 Jun 2006

Discovery of new defect in artery growth

From the beginning, arteries and veins are different in the way they branch into vascular networks, say Dartmouth heart researchers.

9 Jun 2006

Tandem-pore K+ channels mediate inhibition of orexin neurons by glucose

One of the body's basic survival mechanisms is the neural machinery that triggers the hungry brain to the alertness needed for seeking food.

From The University of Manchester 7 Jun 2006

West Nile virus DNA vaccine shows promise in phase 1 trial

Vical Incorporated has announced that in a Phase 1 clinical trial, a West Nile virus (WNV) vaccine candidate administered using Vical's proprietary DNA delivery technology was safe and well tolerated

5 Jun 2006

Siestas may help treat obesity and eating disorders

The Spaniards may have been right all along - a siesta after a hearty lunch is natural, new research suggests.

From The University of Manchester 1 Jun 2006

Finding opens new pathways for treating or preventing autoimmune diseases

A rare genetic defect that can trigger a host of diseases from type 1 diabetes to alopecia has helped explain the imbalance of immune regulator and killer cells in autoimmune disease.

31 May 2006

The ratio of phosphatidylcholine to phosphatidylethanolamine influences membrane integrity and steatohepatitis

An imbalance in the lipid content of the liver appears to trigger the downward spiral that leads some with fatty liver disease to advance to full-blown liver failure, according to a new study in the May Cell Metabolism.

11 May 2006

Study reveals structure of E. coli multidrug transporter protein

This new study could potentially help researchers find new ways to avoid the problem of multidrug resistance and enhance the potency of existing drug compounds.

9 May 2006

A pericellular collagenase directs the 3-D development of white adipose tissue

In the journal Cell, researchers report the serendipitous discovery that the initial development of fat requires a "remodeling" protein that must first make way for the lipid-laden tissue's growth.

8 May 2006

Allergy-free soybeans

Researchers have isolated two Chinese soybean lines that grow without the primary protein linked to soy allergies in children and adults.

8 May 2006

New approaches to genetic disease, based on cells' own ability to correct themselves

New approaches to genetic disease, based on cells' own ability to correct themselves, will be outlined today at the annual conference of the European Society of Human Genetics in Amsterdam, The Netherlands.

8 May 2006

Bacterial binding in the stomach

Scientists have determined that decay-accelerating factor (DAF), a protein found in epithelial cells in the stomach, acts as a receptor for the bacteria Helicobacter pylori. Blocking this interaction could lead to new drugs that reduce the risk of peptic ulcer disease or gastric cancer.

8 May 2006

Inflammation markers identify fatigue in breast cancer survivors

Researchers at the University of California, Los Angeles have defined conditions associated with disabling fatigue that persists for years in almost a third of breast cancer survivors, according to a study in the May 1 issue of Clinical Cancer Research.

3 May 2006