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Genetic variant may explain why some people of African ancestry have lower HIV viral loads

An international team of researchers has found a genetic variant that may explain why some people of African ancestry have naturally lower viral loads of HIV, reducing their risk of transmitting the virus and slowing progress of their own illness.

2 Aug 2023

Antiviral protein protects against COVID-19 in live mouse models

A mammalian protein previously shown by UT Southwestern microbiologists to inhibit the virus that causes COVID-19 in cell culture also protected live mouse models, significantly limiting infection in the lung cells and diminishing the symptoms.

1 Aug 2023

How did trends in invasive bacterial diseases change during the first 2 years of the COVID-19 pandemic?

Researchers analyzed the surveillance data submitted by the Invasive Respiratory Infection Surveillance Consortium.

1 Aug 2023

Monoclonal antibody shows promise in slowing progression of ALS

New research reveals a type of monoclonal antibody already tested in certain forms of cancer may be a promising treatment in stopping the progression of amyotrophic lateral sclerosis, or ALS, a fatal neurodegenerative disease.

31 Jul 2023

Study offers new insight into how antimicrobial resistance emerges in patients with bacterial infections

A research study led by the University of Oxford provides a transformational new insight into how antimicrobial resistance (AMR) emerges in patients with bacterial infections.

31 Jul 2023

New collaboration to investigate forms of RNA modification

Universität Mainz Institute of Pharmaceutical and Biomedical Sciences of Mainz University to collaborate with Monash University and ETH Zurich to investigate forms of RNA modification.

27 Jul 2023

Researchers discover a protein that plays critical roles in alerting the body to a bacterial infection

A team led by researchers at Massachusetts General Hospital (MGH) has discovered a protein that plays critical roles in alerting the body to a bacterial infection and initiating an effective immune response to fight back against the invasion.

27 Jul 2023

NIAID awards $13.7 million grant to investigate multidrug resistant organisms in nursing homes

The National Institute of Allergy and Infectious Diseases (NIAID) has awarded a $13.7 million, five-year grant to a team of researchers to investigate multidrug resistant organisms (MDROs) in nursing homes throughout the United States.

25 Jul 2023

Primary cilia play a critical role in growth plate regeneration

Growth plates (GP), situated at the ends of long bones in children, supply chondrocytes necessary for bone growth.

25 Jul 2023

Discovery redefines current understanding of immune cell landscape in the human cornea

University of Melbourne researchers have discovered that the sentinels guarding the healthy human cornea from pathogens and inflammation are T cells, and not another type of immune cells called dendritic cells, as previously thought.

24 Jul 2023

Improving gut health may be key to slowing HIV progression to AIDS

Restoring and improving gut health may be key to slowing HIV progression to AIDS, according to a new study by University of Pittsburgh infectious diseases scientists published today in the journal JCI Insight.

24 Jul 2023

Cancer-causing gene also plays a crucial role in aging, study finds

A gene called Myc (pronounced "mick") that is among the most important drivers of cancer in both mice and humans also plays a newly discovered crucial role in aging, according to a new Cell Reports study by researchers at UPMC Children's Hospital of Pittsburgh and the University of Pittsburgh School of Medicine.

24 Jul 2023

Probiotic may help prevent cognitive decline during aging

Findings from a new study suggest that taking a probiotic could help prevent the decline in memory and thinking that can accompany aging.

24 Jul 2023

New $7 million grant supports research on how environmental chemicals impact gut microbiome

Worldwide, high rates of obesity and other inflammatory conditions are associated with increased risk for cancer, cardiovascular disease and type 2 diabetes.

21 Jul 2023

Using bacteriophages to treat bladder infections

About one in two women are affected by cystitis during her lifetime, and many suffer from recurrent urinary tract infections.

21 Jul 2023

Probiotic combination could reduce incidence of toxic shock syndrome

The widespread, pathogenic microbe Staphylococcus aureus can colonize the skin and mucous membranes throughout the body, particularly the vagina and gastrointestinal tract.

21 Jul 2023

Researchers discover new way to target bacterial cell wall

The bacterial cell wall must be constantly remodeled in order to grow and divide. This involves the close coordination of lytic enzymes and peptidoglycan synthesis.

20 Jul 2023

T cells can be used to identify type 1 diabetes risk, study shows

Scripps Research scientists have shown that analyzing a certain type of immune cell in the blood can help identify people at risk of developing type 1 diabetes, a life-threatening autoimmune disease.

19 Jul 2023

Using single-cell mass spectrometry to study antimicrobial treatment failure

Laura-Isobel McCall, Ph.D., and Zhibo Yang, Ph.D., co-principal investigators and associate professors of chemistry and biochemistry in the Dodge Family College of Arts and Sciences at the University of Oklahoma, have been awarded a prestigious R01 grant from the National Institutes of Health for their project, "Novel single-cell mass spectrometry to assess the role of intracellular drug concentration and metabolism in antimicrobial treatment failure."

19 Jul 2023

Study sheds light on how viruses override host cell's DNA replication machinery

University of Pittsburgh researchers have shown for the first time how Merkel cell polyomavirus (MCV), which causes an aggressive skin cancer called Merkel cell carcinoma, initiates DNA replication in host cells.

17 Jul 2023