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Achillion Pharmaceuticals receives NIH SBIR grant for study of novel antibacterial compound series

Achillion Pharmaceuticals, Inc., a leader in the discovery and development of small molecule drugs to combat the most challenging infectious diseases, today announced that it has received a Phase 1 Small Business Innovation Research Grant (SBIR) from the National Institute of Allergy and Infectious Disease (NIAID) branch of the National Institutes of Health (NIH) for the further study and characterization of a back-up series of compounds related to its novel antibacterial, ACH-702.

18 Mar 2010

TCAD therapy superior to double combinations and monotherapy against influenza viruses

Adamas Pharmaceuticals, Inc., a privately held company, announced today results from in vivo animal studies and in vitro tests demonstrating that its triple combination antiviral drug (TCAD) therapy is superior relative to double combinations and monotherapy against multiple strains of pandemic and avian influenza viruses. Results of these studies were presented Sunday evening in an oral session at the XII International Symposium on Respiratory Viral Infections being held in Taipei.

15 Mar 2010

FDA looks into supply chain of black and red pepper as part of Salmonella Montevideo investigation

As part of the Salmonella Montevideo investigation, the Food and Drug Administration has been actively investigating the supply chain of black and red pepper supplied to Daniele International Inc., Pascoag, R.I.

15 Mar 2010

Immunizing children against seasonal influenza can protect unvaccinated community against influenza

Results of a clinical trial conducted in a largely self-contained religious community during the 2008-09 influenza season show that immunizing children against seasonal influenza can significantly protect unvaccinated community members against influenza as well. The study was conducted to determine if immunized children could act as a barrier to limit the spread of influenza to the wider, unvaccinated community, a concept known as herd immunity.

15 Mar 2010

ampliPHOX detection technology of InDevR in beta site-testing in anticipation of upcoming product launch

InDevR, developer of advanced life science products, announced that its ampliPHOX Colorimetric Detection Technology is being beta site-tested in anticipation of an upcoming product launch. The original intellectual property was licensed from the University of Colorado at Boulder.

12 Mar 2010

TaiGen Biotechnology's nemonoxacin Phase II study in DFI meets primary endpoints

TaiGen Biotechnology Co., Ltd. announced today the Phase II trial of nemonoxacin (TG-873870) in Diabetic Foot Infection (DFI) with once-a-day dosing met the primary endpoints and showed promising clinical efficacy and good tolerability.

12 Mar 2010

bioMerieux introduces FDA cleared chromID VRE for detecting Enterococcus faecium and Enterococcus faecalis

bioMerieux – a world leader in the field of in vitro diagnostics – today announced the launch of the first Food and Drug Administration (FDA) cleared chromID™ VRE, a simple and cost-effective solution in the struggle against vancomycin-resistant enterococci (VRE). chromID VRE is the first to receive an FDA 510(k) clearance for the qualitative detection of Enterococcus faecium and Enterococcus faecalis showing acquired resistance to vancomycin in stool specimens.

12 Mar 2010

Genetic mutation in African-American men with family history of prostate cancer discovered

Shahriar Koochekpour, MD, PhD, Assistant Professor of Microbiology and Immunology, Biochemistry and Molecular Biology, and Genetics at LSU Health Sciences Center New Orleans, led research that has discovered, for the first time, a genetic mutation in African-American men with a family history of prostate cancer who are at increased risk for the disease.

11 Mar 2010

Accelr8 Technology to present results of culture-free, quantitative pathogen identification study at 110th ASM

Accelr8 Technology Corporation today announced that it has received acceptance to present results for a study on 2-hour, culture-free, quantitative pathogen identification. The study was co-authored with principal investigators at the Denver Health Medical Center and the Barnes-Jewish Hospital in St. Louis.

10 Mar 2010

Cempra Pharmaceuticals completes Phase 1 clinical trials of CEM-101 macrolide

Cempra Pharmaceuticals today announced the successful completion of Phase 1 clinical trials of its oral formulation of CEM-101, which showed good tolerability in those studies. The company also announced plans to submit an IND to the FDA to begin a Phase 1 study with the company's intravenous formulation of CEM-101 in mid-2010.

10 Mar 2010

Sonic hedgehog gene also at work in the ectoderm

Sonic hedgehog, a gene that plays a crucial rule in the positioning and growth of limbs, fingers and toes, has been confirmed in an unexpected place in the embryos of developing mice - the layer of cells that creates the skin.

10 Mar 2010

New reservoir for hidden HIV-infected cells identified

University of Michigan scientists have identified a new reservoir for hidden HIV-infected cells that can serve as a factory for new infections. The findings, which appear online March 7 in Nature Medicine, indicate a new target for curing the disease so those infected with the virus may someday no longer rely on AIDS drugs for a lifetime.

9 Mar 2010

U-M scientists identify new reservoir for hidden HIV-infected cells that can serve as factory for new infections

8 Mar 2010

Scientists identify the role of vitamin D in activation of T cells

Scientists at the University of Copenhagen have discovered that Vitamin D is crucial to activating our immune defenses and that without sufficient intake of the vitamin, the killer cells of the immune system - T cells - will not be able to react to and fight off serious infections in the body.

8 Mar 2010

Salmonella Montevideo outbreak: FDA investigates Daniele International's pepper supply chain

6 Mar 2010

TSO3 new generation sterilizers allowed CE Mark labeling

TSO3 Inc., an innovator in sterilization technology for medical devices in healthcare settings using ozone, today announced that documentation supplied to the European Notified Body conforms to the new Medical Device Directive for Class IIb medical devices; an enhanced European standard to be enforced starting April 2010. This notification allows the Company to label its new generation sterilizers with the CE Mark, which is a requirement to place products in the European Union; the second largest sterilization market after the United States.

5 Mar 2010

Gene involved in susceptibility and resistance to TB identified

University of Washington researchers have identified a gene involved in susceptibility and resistance to tuberculosis. This same gene, they have found, has a role in the severity of leprosy, which is caused by a related pathogen. The researchers also have learned why this gene is important for susceptibility.

5 Mar 2010

Vaccine researchers at HZI find c-di-IMP molecule, more effective than known adjuvants

The adjuvants present in vaccines have a bad reputation. For most people, they are only unnecessary compounds within a medicinal product. This is a misunderstanding since adjuvants have a critical impact on the success of a vaccination. In the best case scenario, one single vaccination shot would be now sufficient for conferring life-long protection.

3 Mar 2010

Consumption of animal products contaminated with mycotoxins affects human health

EUREKA project E! 3025 MONALISA has developed a new, completely natural alternative to using antibiotics in animal feed. Formerly used as growth promoters and to prevent the damaging effects of the fungal toxins which are often present in feed, antibiotics have been prohibited for use in animal feed in the EU since 2006 - creating a need for a new, effective antimycotoxic agent.

1 Mar 2010

Breastfeeding and better hygiene may protect against peptic ulcer bacterium infection

Young children in developing countries are infected at an early age with the bacterium Helicobacter pylori, which can cause peptic ulcers and stomach cancer. New findings show that childrens´ immune responses help in fighting the bacteria. In addition, breastfeeding and better hygiene appear to protect against infection. The results provide hope for a vaccine, according to research from the Sahlgrenska Academy at the University of Gothenburg, Sweden.

1 Mar 2010

Microbiology News and Research

Achillion Pharmaceuticals receives NIH SBIR grant for study of novel antibacterial compound series

TCAD therapy superior to double combinations and monotherapy against influenza viruses

FDA looks into supply chain of black and red pepper as part of Salmonella Montevideo investigation

Immunizing children against seasonal influenza can protect unvaccinated community against influenza

ampliPHOX detection technology of InDevR in beta site-testing in anticipation of upcoming product launch

TaiGen Biotechnology's nemonoxacin Phase II study in DFI meets primary endpoints

bioMerieux introduces FDA cleared chromID VRE for detecting Enterococcus faecium and Enterococcus faecalis

Genetic mutation in African-American men with family history of prostate cancer discovered

Accelr8 Technology to present results of culture-free, quantitative pathogen identification study at 110th ASM

Cempra Pharmaceuticals completes Phase 1 clinical trials of CEM-101 macrolide

Sonic hedgehog gene also at work in the ectoderm

New reservoir for hidden HIV-infected cells identified

U-M scientists identify new reservoir for hidden HIV-infected cells that can serve as factory for new infections

Scientists identify the role of vitamin D in activation of T cells

Salmonella Montevideo outbreak: FDA investigates Daniele International's pepper supply chain

TSO3 new generation sterilizers allowed CE Mark labeling

Gene involved in susceptibility and resistance to TB identified

Vaccine researchers at HZI find c-di-IMP molecule, more effective than known adjuvants

Consumption of animal products contaminated with mycotoxins affects human health

Breastfeeding and better hygiene may protect against peptic ulcer bacterium infection

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