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H5N1 protein hides in tiny tubules

A protein found in the virulent avian influenza virus strain called H5N1 forms tiny tubules in which it "hides" the pieces of double-stranded RNA formed during viral infection, which otherwise would prompt an antiviral immune response from infected cells, said Baylor College of Medicine researchers in an online report in the journal Nature.

6 Nov 2008

Most adults not up to date on their vaccinations

Most adults are not up to date on their vaccinations, says a new report from Harvard Medical School.

5 Nov 2008

Parasites that live inside cells use loophole to thwart immune system

St. Jude Children's Research Hospital scientists have discovered a mechanism by which intracellular pathogens can shut down one of the body's key chemical weapons against them: nitric oxide. The researchers found that the microbes block nitric oxide production by subverting the biochemical machinery used by immune cells called macrophages to produce the chemical.

3 Nov 2008

New strategy to treat human infections caused by the yeast Candida albicans

Researchers at Georgetown University Medical Center (GUMC) have successfully tested a genetic strategy designed to improve treatment of human infections caused by the yeast Candida albicans, ranging from diaper rash, vaginitis, oral infections (or thrush which is common in HIV/AIDS patients), as well as invasive, blood-borne and life-threatening diseases.

27 Oct 2008

The sooner the better when it comes to HIV/AIDS treatment

New research into HIV/AIDS therapy has found that starting treatment with drugs for the AIDS virus may be better sooner than later as victims are more than 70% less likely to die when they started taking cocktails of HIV drugs earlier than currently recommended.

27 Oct 2008

Gates Foundation grant to help prevent deaths in Africa by improving antibiotic access

The Alliance for the Prudent Use of Antibiotics (APUA) has announced a $1.37 million grant from the Bill & Melinda Gates Foundation, to explore ways of reducing millions of preventable deaths from severe respiratory and diarrheal infections in Africa. This project was announced in conjunction with a colloquium at the annual ICAAC/IDSA meeting warning of increasing antibiotic resistance.

26 Oct 2008

Advancing medical research

Researchers from the University of Essex and medical counterparts from Colchester Hospital University NHS Foundation Trust are working together to develop successful partnerships in advancing medical research.

26 Oct 2008

Contact lenses are home to pathogenic amoebae

Contact lenses increase the risk of infection with pathogenic protozoa that can cause blindness. New research, published in the November issue of the Journal of Medical Microbiology, shows that a high percentage of contact lens cases in Tenerife are contaminated with Acanthamoeba that cannot be killed by normal contact lens solution.

20 Oct 2008

$2 egg-beater - low-cost centrifuge replacement - could save lives in developing countries

Plastic tubing taped to a handheld egg-beater could save lives in developing countries, the Royal Society of Chemistry's journal Lab on a Chip reports.

16 Oct 2008

New rapid test for rare leukemia

A new twist on a well-known cell sorting technique may allow physicians to diagnose rare leukemias in hours instead of weeks, according to a study by researchers at the Stanford University School of Medicine and UC-San Francisco.

6 Oct 2008

Disinfectants can make bacteria resistant to treatment

Chemicals used in the environment to kill bacteria could be making them stronger, according to a paper published in the October issue of the journal Microbiology. Low levels of these chemicals, called biocides, can make the potentially lethal bacterium Staphylococcus aureus remove toxic chemicals from the cell even more efficiently, potentially making it resistant to being killed by some antibiotics.

6 Oct 2008

New way to control protein activity could lead to cancer therapies

Investigators at the Stanford University School of Medicine have found a way to quickly and reversibly fine-tune the activity of individual proteins in cells and living mammals, providing a powerful new laboratory tool for identifying - more precisely than ever before - the functions of different proteins.

28 Sep 2008

Coles contaminated chicken recalled in four states

The discovery that packs of pre-sliced chicken sold by the supermarket chain Coles were contaminated with listeria, has prompted a recall of the product from stores in New South Wales, South Australia, Victoria and Queensland and Coles Online.

23 Sep 2008

Tuberculosis researchers discuss challenges, next steps for addressing XDR-TB, MDR-TB in Africa at TB symposium

As many as 30% of people with drug-resistant tuberculosis can be successfully treated with first-line drugs, Paul van Helden of the University of Stellenbosch's Center of Excellence for Biomedical TB Research said recently while presenting research on drug-resistant TB at a TB symposium in Maputo, Mozambique, Africa Science News Service reports.

22 Sep 2008

Breast cancer vaccine could protect against aggressive HER2-positive breast tumours

Women with a certain type of breast cancer have been given hope in the form of a vaccine which promises to eliminate the cancer tumours.

16 Sep 2008

Vaccine against HER2-positive breast cancer offers complete protection in lab

Researchers at Wayne State University have tested a breast cancer vaccine they say completely eliminated HER2-positive tumors in mice - even cancers resistant to current anti-HER2 therapy - without any toxicity.

15 Sep 2008

DNA vaccine developed at the Karmanos Cancer Institute fights HER2-positive cancers

Researchers at the Barbara Ann Karmanos Cancer Institute and Wayne State University School of Medicine have developed a HER2 DNA vaccine that has shown to be effective on drug resistant tumors in mice. The study was reported in the September 15 issue of Cancer Research, a journal of the American Association for Cancer Research.

15 Sep 2008

Drug-resistant plague - A bioterrorism concern?

The bacterium responsible for the "Black Plague," which led to the deaths of over 75 million people worldwide in the 14th century, may have other nasty tricks. Yersinia pestis can normally be treated and cured with a course of antibiotics, if caught within a few days of the symptoms.

11 Sep 2008

Infectious heart disease death rates rising again say scientists

Infectious heart disease is still a major killer in spite of improvements in health care, but the way the disease develops has changed so much since its discovery that nineteenth century doctors would not recognise it, scientists heard today (Thursday 11 September 2008) at the Society for General Microbiology's Autumn meeting being held this week at Trinity College, Dublin.

10 Sep 2008

Protein opens hope of treatment for cystic fibrosis patients

Scientists have finally identified a direct role for the missing protein that leaves cystic fibrosis patients open to attack from lung-damaging bacteria, the main reason most of them die before their 35th birthday, scientists heard today (Thursday 11 September 2008) at the Society for General Microbiology's Autumn meeting being held this week at Trinity College, Dublin.

10 Sep 2008