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Researchers provide evidence supporting need for gender-specific anti-inflammatory drugs

Perhaps you have come across the titles 'Men are from Mars, women are from Venus' or 'Why men don't listen and women can't read maps': just two of the many books and articles -- some enlightening or amusing and others irritating -- that theorise about fundamental differences between men and women.

26 Jul 2017

CUMC researchers capture first snapshot of key brain receptor in action

Columbia University Medical Center researchers have captured the first three-dimensional snapshots of the AMPA-subtype glutamate receptor in action. The receptor, which regulates most electrical signaling in the brain, is involved in several important brain activities, including memory and learning.

24 Jul 2017

Lunatic fringe gene plays role in regulating fate of neural stem cells

The discovery that the brain can generate new cells - about 700 new neurons each day - has triggered investigations to uncover how this process is regulated.

19 Jul 2017

New technique physically expands tissues to improve breast cancer diagnosis

A Ludwig Cancer Research study offers pathologists a quick, cheap and reliable tool to diagnose diseases such as early breast cancer with a conventional optical microscope.

18 Jul 2017

New optical clearing method helps analyze 3D structure of dangerous blood clots

A new technique that makes blood clots optically clear is allowing researchers to use powerful optical microscopy techniques to study the 3D structure of dangerous clots for the first time.

17 Jul 2017

Immune system controls eye tissue regeneration in zebrafish, research finds

Researchers at Johns Hopkins Medicine report evidence that zebrafishes' natural ability to regenerate their eyes' retinal tissue can be accelerated by controlling the fishes' immune systems.

17 Jul 2017

Researchers discover potential substitutes for BPA that lack adverse effects

Researchers at Baylor College of Medicine have identified a group of potential substitutes for bisphenol A (BPA) that lack the adverse effects typically associated with BPA.

14 Jul 2017

Optical clearing technique reveals fine structure of the heart

A technique borrowed from neuroscience to see through brain tissue is helping scientists to see the fine structure of the heart.

12 Jul 2017

Cell cannibalism may have role to play in resisting cancer growth

Cell cannibalism in tumor samples has been observed for over a century, yet this unusual behavior is not well studied.

11 Jul 2017

Brazilian researchers reveal nanoparticle-based strategy to combat antibiotic-resistant bacteria

A new strategy to combat antibiotic-resistant bacteria has been described by Brazilian researchers in Scientific Reports, an online journal owned by Springer Nature.

11 Jul 2017

High-resolution imaging provides new insights into pathological mechanisms of brain diseases

To fully understand brain function and dysfunction, it is important to be able to visualize changes in anatomy and activity in the whole brain.

10 Jul 2017

Researchers discover that amount of Epac2A at vesicles controls insulin release

Specialized beta cells in the pancreas release the hormone insulin to control our blood glucose levels, and failure of this mechanism is central to the development of type-2 diabetes.

10 Jul 2017

Zirconia-doped ceria nanoparticles can act as effective antioxidants in sepsis treatment

During sepsis, cells are swamped with reactive oxygen species generated in an aberrant response of the immune system to a local infection.

6 Jul 2017

Researchers develop new method to visualize whole-body cancer metastasis at single-cell level

Researchers at the RIKEN Quantitative Biology Center and the University of Tokyo have developed a method to visualize cancer metastasis in whole organs at the single-cell level.

6 Jul 2017

Scientists provide detailed view of tau protein structures found in Alzheimer's disease

New research by scientists at the MRC Laboratory of Molecular Biology in the United Kingdom and Indiana University School of Medicine gives the most detailed view yet of tau protein structures found in Alzheimer's disease.

6 Jul 2017

Alzheimer’s disease specific brain deposits photographed for the first time in vivid detail

Scientists from the Britain's Medical Research Council Laboratory of Molecular Biology have for the first time, clearly pictured what the deposits typically seen in a person with Alzheimer’s disease look like. This is a breakthrough in neurodegenerative diseases. The latest study showing the structure of tau protein was published in the journal Nature.

5 Jul 2017

Rhodanine-based compounds show inhibitory activity to prevent aggregation of Tau proteins

The design of tailored peptide-polymer conjugates as drug-specific formulation additives offers access to next generation precision additives that can render problematic small organic drugs water-soluble and improve bioavailability.

30 Jun 2017

Scientists discover, count and determine new mitochondrial proteome in baker's yeast

Mitochondria, best known for their role as powerhouses of eukaryotic cells, fulfill numerous vital functions. Knowledge about the precise protein composition as well as the functions of individual proteins is essential to understand fundamental processes of cell biology and diseases that are caused by cellular defects.

29 Jun 2017

Study: Gadolinium may accumulate in brain tissues of patients without intracranial abnormalities

Minute traces of gadolinium, the contrast agent used to enhance MR images, are often retained in the brain tissue of patients years after undergoing MRI. Some studies have suggested this deposition was limited to patients with underlying brain pathology, such as a tumor or infection.

28 Jun 2017

Researchers shed light on molecular mechanisms of ovarian cancer metastasis

With 20,000 diagnoses each year, ovarian cancer is the ninth most common cancer and fifth leading cause of cancer death among women in the United States.

28 Jun 2017

Microscopy News and Research

Researchers provide evidence supporting need for gender-specific anti-inflammatory drugs

CUMC researchers capture first snapshot of key brain receptor in action

Lunatic fringe gene plays role in regulating fate of neural stem cells

New technique physically expands tissues to improve breast cancer diagnosis

New optical clearing method helps analyze 3D structure of dangerous blood clots

Immune system controls eye tissue regeneration in zebrafish, research finds

Researchers discover potential substitutes for BPA that lack adverse effects

Optical clearing technique reveals fine structure of the heart

Cell cannibalism may have role to play in resisting cancer growth

Brazilian researchers reveal nanoparticle-based strategy to combat antibiotic-resistant bacteria

High-resolution imaging provides new insights into pathological mechanisms of brain diseases

Researchers discover that amount of Epac2A at vesicles controls insulin release

Zirconia-doped ceria nanoparticles can act as effective antioxidants in sepsis treatment

Researchers develop new method to visualize whole-body cancer metastasis at single-cell level

Scientists provide detailed view of tau protein structures found in Alzheimer's disease

Alzheimer’s disease specific brain deposits photographed for the first time in vivid detail

Rhodanine-based compounds show inhibitory activity to prevent aggregation of Tau proteins

Scientists discover, count and determine new mitochondrial proteome in baker's yeast

Study: Gadolinium may accumulate in brain tissues of patients without intracranial abnormalities

Researchers shed light on molecular mechanisms of ovarian cancer metastasis

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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