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Massive brain imaging project awarded Keck Foundation grant

Tantalizing treasures of neural knowledge that lie deep in the brain of the common fruit fly are one step closer to being laid bare, now that a team of six Stanford researchers has been awarded a $1.3 million medical research grant by the W. M. Keck Foundation.

4 Feb 2008

New discovery, immune cells confront viruses just inside of the lymph node

Vaccines have led to many of the world's greatest public health triumphs, but many deadly viruses, such as HIV, still elude the best efforts of scientists to develop effective vaccines against them. An improved understanding of how the immune system operates during a viral infection is critical to designing successful anti-virus vaccines.

4 Feb 2008

Direct sequencing of single RNA strands with tip-enhanced Raman spectroscopy

The genetic alphabet contains four letters. Although our cells can readily decipher our genetic molecules, it isn't so easy for us to read a DNA sequence in the laboratory. Scientists require complex, highly sophisticated analytical techniques to crack individual DNA codes.

28 Jan 2008

JDSU advances the world of polarization optics

JDSU is advancing the world of polarization optics with today's announcement of its ability to combine thin-film and liquid crystal polymer technologies to produce high-quality custom birefringent components.

22 Jan 2008

Previously unknown chromosomal abnormalities play substantial role in autism

Genome-wide scans of families affected by autism spectrum disorder (ASD) have revealed new evidence that previously unknown chromosomal abnormalities have a substantial role in the prevalent developmental disorder, according to a report published online Jan. 17th in the American Journal of Human Genetics, a publication of Cell Press.

18 Jan 2008

An emerging candidate for protecting patients from liver injury after abdomen surgery

Many patients worldwide are going to receive major abdomen surgery or intestine transplantation every year and expect to be afflicted with liver injury afterwards.

17 Jan 2008

Nanomechanical analysis of cells from cancer patients

A multidisciplinary team of scientists from the University of California, Los Angeles (UCLA), were able to differentiate metastatic cancer cells from normal cells in patient samples by utilizing a modified form of atomic force microscopy (AFM) to measure the softness of the cells.

16 Jan 2008

Monkey malaria more widespread in Malaysian people than previously thought

A potentially fatal species of malaria is being commonly misdiagnosed as a more benign form of the disease, thereby putting lives at risk, according to research funded by the Wellcome Trust and the University Malaysia Sarawak.

16 Jan 2008

U.S. Food and Drug Administration approves new genetic breast cancer test

The U.S. Food and Drug Administration has approved a test that helps in assessing the risk of tumor recurrence and long-term survival for patients with relatively high-risk breast cancer. The TOP2A FISH pharmDx is the first approved device to test for the TOP2A (topoisomerase 2 alpha) gene in cancer patients.

14 Jan 2008

Gene detection platform made from self-assembled DNA nanostructures

Scientists at Arizona State University's Biodesign Institute have developed the world's first gene detection platform made up entirely from self-assembled DNA nanostructures.

11 Jan 2008

Discovery of a core mechanism underlying Fragile X syndrome

Researchers at UT Southwestern Medical Center are uncovering how brain cells are affected in Fragile X syndrome, the most common cause of inherited mental retardation and the most common genetic cause of autism.

9 Jan 2008

New understanding on the mechanics of gene transcription

The molecular machinery behind gene transcription -- the intricate transfer of information from a segment of DNA to a corresponding strand of messenger RNA -- isn't stationed in special "transcription factories" within a cell nucleus, according to Cornell researchers.

9 Jan 2008

Loss of a small portion of chromosome 16 linked to autism

Loss of a small portion of chromosome 16, known as 16p11.2, is significantly associated with autism report researchers from the University of Chicago Medical Center, the University of Illinois at Chicago, and the Roswell Park Cancer Institute in an article, published Dec. 21, 2007, online by the journal Human Molecular Genetics.

9 Jan 2008

Insights into cell movement likely to aid immune study, cancer research

Scientists at Washington University School of Medicine in St. Louis have used yeast cells to better understand a collection of proteins associated with the formation of actin networks, which are essential to cell movement.

9 Jan 2008

Tracking down allergenic substances

At present, animal tests are the only way of determining whether a particular chemical can cause an allergic reaction.

7 Jan 2008

Intracellular bacterial communities in cystitis; rifapentine cures TB in mouse model; and more

A study published this week in the open access journal PLoS Medicine presents convincing evidence that intracellular bacterial communities (IBCs) commonly exist in women with bladder infections and may contribute to the recurrence of these infections.

18 Dec 2007

Bacteria that cause urinary tract infections invade bladder cells

Scientists at Washington University School of Medicine in St. Louis have found definitive proof that some of the bacteria that plague women with urinary tract infections (UTIs) are entrenched inside human bladder cells.

18 Dec 2007

Breakthrough technology provides new understanding of cellular processes endocytosis and exocytosis

For the first time, scientists at Weill Cornell Medical College in New York City have observed in real time a cellular mechanism that's crucial to how brain cells communicate.

17 Dec 2007

Researchers report protein interactions of MAP kinase signaling pathway

The Stowers Institute's Rong Li Lab, in collaboration with the Institute's Imaging Center, has achieved a quantitative in vivo measurement of the dynamic protein-protein interactions in the mitogen-activated protein (MAP) kinase cascade signaling pathway, which is critical to growth and differentiation decisions in all eukaryotic cells.

14 Dec 2007

Researchers shine the light of venus to learn how the herpes virus invades cells

University of Pennsylvania researchers have uncovered an important step in how herpes simplex virus, HSV-1, uses cooperating proteins found on its outer coat to gain entry into healthy cells and infect them.

14 Dec 2007