Mitochondria News and Research

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Study suggests autophagy is involved in the onset of vascular dementia

Autophagy is a basic catabolic mechanism by which unnecessary or dysfunctional cellular components are degraded by lysosomes.

12 Aug 2014

Researchers discover how arginine starvation specifically kills cancer cells

Researchers at UC Davis, City of Hope, Taipai Medical University and National Health Research Institutes in Taiwan have discovered how a drug that deprives the cells of a key amino acid specifically kills cancer cells.

12 Aug 2014

Biologists identify signaling pathway that switches on calorie-burning process in brown fat cells

Biologists at The Scripps Research Institute (TSRI) have identified a signaling pathway that switches on a powerful calorie-burning process in brown fat cells.

1 Aug 2014

Mice lacking specific protein live longer lives with fewer age-related illnesses

While developing a new cancer drug, researchers at The Wistar Institute discovered that mice lacking a specific protein live longer lives with fewer age-related illnesses.

31 Jul 2014

Researchers identify RNA that modulates action of important gene in process of programmed cell death

Researchers from the University of S-o Paulo (USP) have identified an RNA known as INXS that, although containing no instructions for the production of a protein, modulates the action of an important gene in the process of apoptosis, or programmed cell death.

31 Jul 2014

Researchers discover new function of body's most important tumor-suppressing protein

Researchers at Cold Spring Harbor Laboratory (CSHL) have discovered a new function of the body's most important tumor-suppressing protein. Called p53, this protein has been called "the guardian of the genome."

30 Jul 2014

Study provides potential drug targets for transient cerebral ischemia-reperfusion injury

Mitochondria play an important role in neuronal apoptosis caused by cerebral ischemia. Researchers at the Affiliated Hospital of Qingdao University, China discovered transient ischemia led to cell apoptosis in the hippocampus and changes in memory and cognition of aged rats.

26 Jul 2014

Clinical study aims to validate preventive treatment against tumor metastasis

Metastasis, the strategy adopted by tumor cells to transform into an aggressive form of cancer, are often associated with a gloomy prognosis. Managing to block the metastasis or, even better, prevent their formation would be a giant step towards the fight against cancer.

25 Jul 2014

UT Southwestern researcher named recipient of ASBMB Merck Award for research on molecular biology

Dr. Zhijian "James" Chen, Professor of Molecular Biology and a Howard Hughes Medical Institute investigator at UT Southwestern Medical Center, has been named the 2015 recipient of the American Society for Biochemistry and Molecular Biology Merck Award, which recognizes outstanding contributions to research in biochemistry and molecular biology.

18 Jul 2014

Researchers examine why antioxidant actually do more harm than good

For decades, health-conscious people around the globe have taken antioxidant supplements and eaten foods rich in antioxidants, figuring this was one of the paths to good health and a long life.

11 Jul 2014

New pathway to disabling disease: blocking bacteria's access to iron in the body

In an era of increasing concern about the prevalence of antibiotic-resistant illness, Case Western Reserve researchers have identified a promising new pathway to disabling disease: blocking bacteria's access to iron in the body.

10 Jul 2014

Exeter scientists find health benefits in rotten egg gas

It may smell of flatulence and have a reputation for being highly toxic, but when used in the right tiny dosage, hydrogen sulfide is now being being found to offer potential health benefits in a range of issues, from diabetes to stroke, heart attacks and dementia. A new compound (AP39), designed and made at the University of Exeter, could hold the key to future therapies, by targeting delivery of very small amounts of the substance to the right (or key) places inside cells.

10 Jul 2014

Transcription factor IRF4 plays key role in brown fat's thermogenic process

The body contains two types of fat cells, easily distinguished by color: White and brown. While white fat serves to store excess calories until they're needed by the body, brown adipocytes actually burn fat by turning it into heat.

4 Jul 2014

Researchers discover new way by which metabolism is linked to regulation of DNA

A research team at the Faculty of Medicine & Dentistry at the University of Alberta have discovered a new way by which metabolism is linked to the regulation of DNA, the basis of our genetic code. The findings may have important implications for the understanding of many common diseases, including cancer.

4 Jul 2014

FMM supports research project to investigate mitochondria-targeted therapeutic approach

The Foundation for Mitochondrial Medicine announced today that it is working with The Michael J. Fox Foundation for Parkinson's Research to support a research project led by Wolfdieter Springer, PhD, at the Department of Neuroscience at Mayo Clinic in Florida to investigate a mitochondria-targeted therapeutic approach to treating Parkinson's disease.

26 Jun 2014

Research finding could open new opportunities for treating Huntington's disease

Researchers believe they have learned how mutations in the gene that causes Huntington's disease kill brain cells, a finding that could open new opportunities for treating the fatal disorder. Scientists first linked the gene to the inherited disease more than 20 years ago

24 Jun 2014

Alcoholic liver disease: an interview with Dr Vinood Patel, University of Westminster

Alcoholic liver disease (ALD) is one of the leading causes of death worldwide and also in the UK. As its name indicates this disease arises due to consuming excessive amounts of alcohol (80 g/day) over an extended period, normally 10-20 years.

24 Jun 2014

Alternative disposal process in optic nerve cells has implications for neurodegenerative diseases

Biologists have long considered cells to function like self-cleaning ovens, chewing up and recycling their own worn out parts as needed.

20 Jun 2014

New research reveals gene's role in type 1 diabetes

New research describes details of how a diabetes-related gene functions on a biological pathway that affects the release of insulin. The study authors say that finding drugs that act on that pathway may eventually lead to a new treatment for type 1 diabetes.

20 Jun 2014

Susceptibility gene for type 1 diabetes regulates self-destruction of cell's energy factory

A team led by researchers from the Perelman School of Medicine at the University of Pennsylvania found that a susceptibility gene for type 1 diabetes regulates self-destruction of the cell's energy factory. They report their findings this week in Cell.

20 Jun 2014

Mitochondria News and Research

Study suggests autophagy is involved in the onset of vascular dementia

Researchers discover how arginine starvation specifically kills cancer cells

Biologists identify signaling pathway that switches on calorie-burning process in brown fat cells

Mice lacking specific protein live longer lives with fewer age-related illnesses

Researchers identify RNA that modulates action of important gene in process of programmed cell death

Researchers discover new function of body's most important tumor-suppressing protein

Study provides potential drug targets for transient cerebral ischemia-reperfusion injury

Clinical study aims to validate preventive treatment against tumor metastasis

UT Southwestern researcher named recipient of ASBMB Merck Award for research on molecular biology

Researchers examine why antioxidant actually do more harm than good

New pathway to disabling disease: blocking bacteria's access to iron in the body

Exeter scientists find health benefits in rotten egg gas

Transcription factor IRF4 plays key role in brown fat's thermogenic process

Researchers discover new way by which metabolism is linked to regulation of DNA

FMM supports research project to investigate mitochondria-targeted therapeutic approach

Research finding could open new opportunities for treating Huntington's disease

Alcoholic liver disease: an interview with Dr Vinood Patel, University of Westminster

Alternative disposal process in optic nerve cells has implications for neurodegenerative diseases

New research reveals gene's role in type 1 diabetes

Susceptibility gene for type 1 diabetes regulates self-destruction of cell's energy factory

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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