Mitosis News and Research

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Researchers identify genome-organizing mechanism that transmits vital genetic materials during mitosis

Chromosomes are responsible for carrying our genes and essentially protecting the information that helps ensure normal, healthy growth, with vital instructions being passed on from cell to cell by a process known as mitosis. While this copying mechanism has been well understood for decades, scientists have been unable to describe exactly how genetic information is protected and properly segregated as mitosis is happening.

7 Aug 2015

USC researchers develop yeast model to study gene mutation that disrupts DNA duplication

Researchers at USC have developed a yeast model to study a gene mutation that disrupts the duplication of DNA, causing massive damage to a cell's chromosomes, while somehow allowing the cell to continue dividing.

7 Aug 2015

Chromosomes play active role in animal cell division

Canadian and British researchers have discovered that chromosomes play an active role in animal cell division. This occurs at a precise stage - cytokinesis - when the cell splits into two new daughter cells.

14 Jul 2015

Scientists identify novel mechanism that can reorganize cell's genetic architecture to promote senescence

Senescence, a phenomenon in which cells cease to divide and grow, can be caused by everything from natural DNA damage to treatment with chemotherapy. However, several mechanisms allow for cells to bypass senescence and grow out of control, eventually becoming cancerous.

3 Jun 2015

Study reveals new molecular mechanism that helps protect genome from harmful effect of UV radiations

Researchers have uncovered a new molecular mechanism whereby human cells protect their genome from the detrimental effect of UV radiation and govern DNA replication in cellular mitosis, which, when it malfunctions, leads to harmful results.

29 May 2015

Leicester research team identifies potential new targets for cancer treatments

An international consortium of scientists led by a group from the University of Leicester has announced a new advance in understanding the mechanisms of cancer and how to target it more effectively with new treatments...

12 May 2015

Damon Runyon Cancer Research Foundation names 15 new Damon Runyon Fellows

The Damon Runyon Cancer Research Foundation, a non-profit organization focused on supporting innovative early career researchers, named 15 new Damon Runyon Fellows at its fall Fellowship Award Committee review. The recipients of this prestigious, four-year award are outstanding postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators across the country.

31 Jan 2015

ASCB honors UTSA adjunct professor with E. B. Wilson Medal

William Brinkley, adjunct professor of biology in the UTSA College of Sciences, was recently honored with the E. B. Wilson Medal from the American Society for Cell Biology. The medal, the organization's highest honor for far-reaching contributions to cell biology over a lifetime in science, was presented to Brinkley at the 54th Annual Meeting in Philadelphia.

22 Jan 2015

Kinex Pharmaceuticals doses first actinic keratosis patient with KX2-391 ointment

Kinex Pharmaceuticals announced today that the first actinic keratosis patient has been dosed with KX2-391 ointment in Austin, Texas.

20 Jan 2015

New project aims at delivering innovative test to improve safety of chemical products, drugs

The Genotrace project, combining targeted research and technology transfer, aims at delivering an innovative test to improve the safety of chemical products, drugs, human and animal food and the environment.

10 Sep 2014

Research validates Myc inhibition as effective therapeutic strategy for glioma

Research led by the Vall d'Hebron Institute of Oncology (VHIO) evidence the most conclusive preclinical results to-date validating Myc inhibition as a therapeutic strategy in glioma - a highly agressive tumor type that notoriously outsmarts current anti-cancer therapies.

19 Aug 2014

Scientists reveal structure of protein involved in life and development of cancer

Scientists reveal the structure of one of the most important and complicated proteins in cell division - a fundamental process in life and the development of cancer - in research published in Nature today (Sunday).

21 Jul 2014

Study of human embryonic stems cells identifies bottlenecks restricting formation of colonies

A time-lapse study of human embryonic stems cells has identified bottlenecks restricting the formation of colonies, a discovery that could lead to improvement in their use in regenerative medicine.

13 Jun 2014

Analysis of key cellular protein demonstrates the effectiveness of Taxol anti-cancer drug

A pathway to the design of even more effective versions of the powerful anti-cancer drug Taxol has been opened with the most detailed look ever at the assembly and disassembly of microtubules, tiny fibers of tubulin protein that form the cytoskeletons of living cells and play a crucial role in mitosis.

23 May 2014

NCCN receives $2M grant to evaluate effectiveness of volasertib in treatment of hematologic malignancies

The National Comprehensive Cancer Network® (NCCN®) Oncology Research Program (ORP) has been awarded a $2-million grant from Boehringer Ingelheim Pharmaceuticals, Inc.

23 May 2014

B1/Cdk1 protein which plays key role in cell division also boosts power of mitochondrial activity

An international team led by researchers at UC Davis has shown that the cyclin B1/Cdk1 protein complex, which plays a key role in cell division, also boosts the mitochondrial activity to power that process.

18 Apr 2014

Research opens new possibilities for blocking runaway cell division in cancer

The structure of a key part of the machinery that allows cells to divide has been identified by researchers at the University of California, Davis -- opening new possibilities for throwing a wrench in the machine and blocking runaway cell division in cancer.

9 Apr 2014

Stowers team reports genome-wide analysis of genes that drive cell division in multicellular organism

In textbooks, the grand-finale of cell division is the tug-of-war fought inside dividing cells as duplicated pairs of chromosomes get dragged in opposite directions into daughter cells.

3 Apr 2014

Study to understand how protein motor works for development of targeted cancer therapies

Researchers at Warwick Medical School have shown for the first time how a protein motor, Kif15, uses acrobatic flexibility to navigate within the mitotic spindle. Understanding how it works could prove vital for the development of targeted cancer therapies.

27 Mar 2014

Research reveals very unique evolutionary innovations in primate brain

New research by UC Santa Barbara's Kenneth S. Kosik, Harriman Professor of Neuroscience, reveals some very unique evolutionary innovations in the primate brain.

28 Feb 2014