Nanobodies News and Research

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Removing bacterial armor could be new way to fight anthrax

A new study led by Dr. Antonella Fioravanti in the lab of Prof. Han Remaut (VIB-VUB Center for Structural Biology) has shown that removing the armor of the bacterium that causes anthrax slows its growth and negatively affects its ability to cause disease.

16 Jul 2019

Scientists create powerful method for 'directed evolution' of molecules

UNC School of Medicine scientists created a powerful new "directed evolution" technique for the rapid development of scientific tools and new treatments for many diseases.

5 Jul 2019

Researchers develop a new approach to targeting tumors and metastases

The spread of malignant cells from an original tumor to other parts of the body, known as metastasis, is the main cause of cancer deaths worldwide.

7 May 2019

Unusually small antibodies could help CAR T-cell therapies to kill solid tumors

In 1989, two undergraduate students at the Free University of Brussels were asked to test frozen blood serum from camels, and stumbled on a previously unknown kind of antibody. I

12 Apr 2019

Study identifies camelid nanobodies capable of blocking EGF in cancer cells

The natural world often provides the answer to unsolved medical problems. On this occasion, the solution to a challenge posed by cancer has come about from the immune system of camelids.

3 Oct 2018

Newly discovered nanobody holds promise to advance targeted therapies for several diseases

Researchers from Case Western Reserve University School of Medicine have found a nanobody that holds promise to advance targeted therapies for a number of neurological diseases and cancer.

10 Jul 2018

New way of tagging exosomes could have long term benefits in treatment of life-threatening conditions

The development of a new technique for labelling the body’s own transporters – exosomes - could have long term benefits in the treatment of life-threatening medical conditions, including cancer.

28 Sep 2017

New way of tagging exosomes could have long term benefits in treatment of life-threatening conditions

The development of a new technique for labeling the body’s own transporters – exosomes - could have long term benefits in the treatment of life-threatening medical conditions, including cancer.

28 Sep 2017

Scientists manage to permeate living cells with small antibodies

Scientists at the Technische Universität Darmstadt, Ludwig Maximilians University Munich and the Leibniz Institute for Molecular Pharmacology have managed to introduce tiny antibodies into living cells. The researchers now report on the synthesis and applications for these nanobodies in "Nature Chemistry".

19 Jul 2017

Researchers develop new antiviral strategy to combat respiratory syncytial virus

Researchers from VIB, UGent, the Geisel School of Medicine at Dartmouth and several collaborators developed a new antiviral strategy to fight human respiratory syncytial virus (RSV), a leading cause of lower respiratory tract infections in children.

13 Feb 2017

LaVison BioTec highlights Nicolas Renier's research on use of UltraMicroscope to study axon rewiring in nervous systems

LaVison BioTec, developers of advanced microscopy solutions for the life sciences, report on the work of Nicolas Renier, a Post-Doctoral Fellow in the laboratory of Marc Tessier-Lavigne at the Rockefeller University in New York where he applies light sheet microscopy to study axon rewiring in adult nervous systems.

12 May 2016

NIBIB-supported researchers create platelet-like particles to control excessive bleeding, augment clotting

NIBIB-supported researchers have created tiny gel particles that can perform the same essential functions as platelets. The particles could one day be used to control excessive bleeding following traumatic injury or in individuals with impaired clotting due to an inherited condition or as a result of certain medications or chemotherapy.

1 Jul 2015

Vrije University Brussels installs MILabs PET-SPECT-CT-MRI platform for nanobody research

The comprehensive MILabs PET-SPECT-CT-MR preclinical platform combines the best PET-SPECT functional imaging capabilities (sub-half-mm SPECT resolution and sub-mm PET resolution) with high resolution anatomical imaging from an integrated X-ray CT subsystem and/or a compact cryogen free 1.5 T MRI unit

13 Mar 2015

Nanobody Nano-85 holds promise for detection of noroviral RNA

Infection with highly contagious noroviruses, while not usually fatal, can lead to a slew of unpleasant symptoms such as excessive vomiting and diarrhea. Current treatment options are limited to rehydration of the patient. "Additionally, noroviruses come in a variety of constantly evolving strains.

9 Mar 2015

Researchers uncover 3D structure of neuroreceptor

Neurons are the cells of our brain, spinal cord, and overall nervous system. They form complex networks to communicate with each other through electrical signals that are carried by chemicals.

4 Aug 2014

Researchers identify important steps to understand mechanisms underlying pathogenic effect of prions

"When they are healthy, they look like tiny spheres; when they are malignant, they appear as cubes" stated Giuseppe Legname, principal investigator of the Prion Biology Laboratory at the Scuola Internazionale Superiore di Studi Avanzati (SISSA) in Trieste, when describing prion proteins.

25 Jan 2014

Nanobodies News and Research

Removing bacterial armor could be new way to fight anthrax

Scientists create powerful method for 'directed evolution' of molecules

Researchers develop a new approach to targeting tumors and metastases

Unusually small antibodies could help CAR T-cell therapies to kill solid tumors

Study identifies camelid nanobodies capable of blocking EGF in cancer cells

Newly discovered nanobody holds promise to advance targeted therapies for several diseases

New way of tagging exosomes could have long term benefits in treatment of life-threatening conditions

New way of tagging exosomes could have long term benefits in treatment of life-threatening conditions

Scientists manage to permeate living cells with small antibodies

Researchers develop new antiviral strategy to combat respiratory syncytial virus

LaVison BioTec highlights Nicolas Renier's research on use of UltraMicroscope to study axon rewiring in nervous systems

NIBIB-supported researchers create platelet-like particles to control excessive bleeding, augment clotting

Vrije University Brussels installs MILabs PET-SPECT-CT-MRI platform for nanobody research

Nanobody Nano-85 holds promise for detection of noroviral RNA

Researchers uncover 3D structure of neuroreceptor

Researchers identify important steps to understand mechanisms underlying pathogenic effect of prions

Ablynx Nets Another $33.7M From Merck Serono As Partnership Expands

Ablynx Nets Another $33.7M From Merck Serono As Partnership Expands

Abbvie, Ablynx Ink Up To $840M RA, SLE Collaboration

Anti-cancer drug conjugates: an interview with Dr Andreas Menrad, CSO Ablynx and Dr Chris Martin, CEO Spirogen

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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