Nuclear Magnetic Resonance (NMR) News and Research

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New analytical method can develop specific drugs against parasites, bacteria

A team led by Professor Malcolm McConville from the Bio21 Institute, University of Melbourne developed a new analytical method which can be used for many infectious parasites and bacteria.

6 Aug 2011

Decline of citrate concentration may contribute to bone brittleness

Bone is one of nature's surprising "building materials." Pound-for-pound it's stronger than steel, tough yet resilient. Scientists at the U.S. Department of Energy's Ames Laboratory have identified the composition that gives bone its outstanding properties and the important role citrate plays, work that may help science better understand and treat or prevent bone diseases such as osteoporosis.

9 Jun 2011

Berkeley Lab scientists contribute to remarkable advance in nuclear magnetic resonance

Nuclear magnetic resonance, a scientific technique associated with outsized, very low temperature, superconducting magnets, is one of the principal tools in the chemist's arsenal, used to study everything from alcohols to proteins to such frontiers as quantum computing.

19 May 2011

LDL particles may be a more accurate measure of subclinical atherosclerosis than LDL cholesterol

LipoScience, Inc., a highly innovative diagnostic company that is advancing patient care by developing high value proprietary blood tests using nuclear magnetic resonance (NMR) technology, today announced presentations of two clinical studies "from the podium" at the 60th Annual Scientific Session of the American College of Cardiology.

6 Apr 2011

Research offers first structural insights into 'client' protein shape in chaperone presence

In the constantly morphing field of protein structure, scientists at The Scripps Research Institute offer yet another surprise: a common "chaperone" protein in cells thought to help other proteins fold has been shown instead to loosen them.

4 Apr 2011

Journal of Clinical Lipidology publishes LipoScience LDL particle study results against CVD

LipoScience, Inc., a highly innovative diagnostic company that is advancing patient care by developing high value proprietary blood tests using nuclear magnetic resonance technology, today announced publication of a clinical study in the Journal of Clinical Lipidology demonstrating that in many people, low density lipoprotein cholesterol is a less accurate predictor of cardiovascular disease events than LDL particle number.

19 Mar 2011

Harvard Medical School selects Agilent's NMR spectrometer for biomolecular research applications

Agilent Technologies Inc. today announced that Harvard Medical School has selected Agilent's 700-MHz Ultra-High Field Nuclear Magnetic Resonance spectrometer for biomolecular research applications.

25 Feb 2011

Study explores role of proline containing peptides in inhibiting anti-apoptotic function of XIAP

Basic and translational research on cancer, and development of new cancer therapeutics, has focused on different aspects of cancer cellular function. One area of focus is the life and death of a cancer cell. Apoptosis, also known as programmed cell death, is a fundamental process of cells including cancer cells. The signal transduction pathways of apoptosis involve many different proteins and their interactions with each other.

16 Feb 2011

Metabolic profiling of tissue samples may transform the way surgeons make decisions

Metabolic profiling of tissue samples could transform the way surgeons make decisions in the operating theatre, say researchers at a new laboratory being launched today. Scientists at Imperial College London, in partnership with clinicians at Imperial College Healthcare NHS Trust, have installed a high resolution solid state nuclear magnetic resonance (NMR) spectrometer in St Mary's Hospital.

13 Jan 2011

University of Minnesota places order for Bruker's ultra-high field NMR spectrometers

Bruker announces an order valued at over $7.5 million from the University of Minnesota for its new Nuclear Magnetic Resonance (NMR) laboratory, including ultra-high field Avance™ III 900 and Avance™ III 850 NMR spectrometers. The systems will be installed in the newly constructed and greatly expanded NMR Facility at the University of Minnesota.

12 Jan 2011

University of Leicester holds first Doctoral Inaugural Lectures

The University of Leicester Graduate School is holding the first Doctoral Inaugural Lectures of the year on Wednesday, 24 November.

20 Nov 2010

Matrix-Bio's VeraMarker-BCR blood test predicts breast cancer recurrence 13 months before clinical diagnosis

Connie Krabbe understands the fear and foreboding breast cancer survivors feel when visiting their physicians for post-treatment check-ups. Two of her four sisters died of metastatic cancer related to breast cancer, enduring bone, brain, and ovarian cancer before succumbing to the disease in their early 50s.

21 Oct 2010

New combination technique improves study of protein characterization

Using a combination of high-powered computers and advanced experimental magnetic resonance data, a Florida State University biophysical chemist has developed techniques that improve the way scientists can study and predict the structure and dynamics of proteins found in the human body. His innovations could ultimately shorten the time it takes researchers to develop new, more effective drugs and better understand biomedical processes that underlie a variety of health conditions.

12 Oct 2010

Evotec enters multiple target drug discovery collaboration with Shionogi

Evotec AG today announced that it has entered into a multiple target drug discovery collaboration with Shionogi & Co Ltd., to identify small molecule modulators of various protein-protein interaction targets.

5 Oct 2010

Scientists use NMR technology to improve protein purification in drug development

The purification of drug components is a large hurdle facing modern drug development. This is particularly true of drugs that utilize proteins, which are notoriously difficult to separate from other potentially deadly impurities. Scientists within the Center for Biotechnology and Interdisciplinary Studies (CBIS) at Rensselaer Polytechnic Institute are using nuclear magnetic resonance (NMR) to understand and improve an important protein purification process.

30 Sep 2010

UGA researcher receives NIH award for high-risk, high-reward carbohydrate research

The National Institutes of Health has awarded a prestigious EUREKA award to Robert Woods, a professor at the University of Georgia Complex Carbohydrate Research Center, to develop a new method for understanding how antibodies interact with large molecules known as glycans that are a major component of all cell surfaces.

27 Sep 2010

University of Maryland School of Medicine orders AVANCE III 950 US2 NMR spectrometer from Bruker

Bruker Corporation announces a major order from the University of Maryland School of Medicine for its ultra-high field AVANCE III 950 US2 NMR spectrometer. The 950 MHz Nuclear Magnetic Resonance magnet and spectrometer will help University of Maryland researchers to unravel the mysteries of molecules and develop new agents to treat cancer, AIDS and other diseases.

7 Sep 2010

Martin Karplus receives 2010 Russell Varian Prize for NMR innovation

Agilent Technologies Inc. announced Martin Karplus, professor emeritus, Department of Chemistry and Chemical Biology, Harvard University; and Laboratoire de Chimie Biophysique, ISIS, Université Louis Pasteur, the winner of the 2010 Russell Varian Prize.

23 Aug 2010

University of Maryland receives grant from NCRR to acquire superconducting NMR spectrometer

The University of Maryland, in partnership with the University of Maryland, Baltimore and University of Maryland Baltimore County, has received a $7.9 million federal grant to acquire a superconducting 950 MHz Nuclear Magnetic Resonance (NMR) magnet that will help researchers unravel the mysteries of molecules and develop new agents to treat cancer, AIDS and other diseases.

12 Aug 2010

New study uses NMR in drug design

A new study by a team of researchers led by Jeffrey Peng, assistant professor of chemistry and biochemistry at the University of Notre Dame, is using Nuclear Magnetic Resonance, to move drug design into groundbreaking consideration of the dynamic flexibility of drugs and their targets.

20 May 2010