Nucleic Acid News and Research

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Eurofins Medigenomix, Orion Diagnostica Oy sign co-exclusive technology license agreement

Eurofins Medigenomix, a part of the Eurofins Genomics Business line of Eurofins Scientific and Orion Diagnostica Oy, an in vitro diagnostics company specialising in the development, production and sales of diagnostic test systems, announced that they have signed a co-exclusive technology license agreement. Orion Diagnostic Oy owns the global rights for the SIBA- isothermal nucleic acid detection technology in all fields.

17 Dec 2013

Study: Antisense drugs show activity in wide range of tissues and organs

Antisense therapeutics, a class of drugs comprised of short nucleic acid sequences, can target a dysfunctional gene and silence its activity. A new study has shown that antisense drugs delivered systemically show activity in a wide range of tissues and organs, supporting their broad therapeutic potential in many disease indications, as described in an article in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

13 Dec 2013

Gene Expression Barcode 3.0 tool proves to be a vital resource for cancer research

A newly improved internet research tool is helping cancer researchers and physicians make sense out of a deluge of genetic data from nearly 100,000 patients and more than 50,000 mice.

13 Dec 2013

New assay allows rapid and sensitive detection of Chlamydia trachomatis

Researchers have developed a new assay for rapid and sensitive detection of Chlamydia trachomatis, the most common sexually transmitted infection (STI) in humans.

12 Dec 2013

Pronai Therapeutics reports positive results from PNT2258 Phase II study on lymphoma

ProNAi Therapeutics, Inc., a leader in developing nucleic acid therapeutics, presented safety and efficacy data from its ongoing Phase II study yesterday at the 55th Annual Meeting of the American Society for Hematology (ASH) in New Orleans, Louisiana.

11 Dec 2013

Johns Hopkins researchers discover some cases of scleroderma likely to be initiated by cancer

The Scleroderma Research Foundation today reported that researchers at The Johns Hopkins University have discovered that some cases of scleroderma are likely to have been initiated by cancer.

6 Dec 2013

PrimeraDx gets FDA clearance for ICEPlex C. difficile Assay Kit and ICEPlex System

PrimeraDx, a molecular diagnostics company, announced today that the ICEPlex C. difficile Assay Kit and the ICEPlex System have received 510(k) clearance from the United States Food and Drug Administration.

3 Dec 2013

Bruker receives FDA clearance to market MALDI Biotyper CA System in the U.S.

Bruker Corporation today announced that it has been granted U.S. FDA clearance under Section 510(k) to market its MALDI Biotyper CA System in the United States for the identification of Gram negative bacterial colonies cultured from human specimens.

26 Nov 2013

Seed grants support cancer diagnosis and treatment, vascular health research

Five teams of scientists earned research seed grants awarded this year by the John S. Dunn Foundation. The awards support new collaborations by researchers at Rice University's BioScience Research Collaborative (BRC) and their partners at other institutional members of the Gulf Coast Consortia (GCC).

26 Nov 2013

Cleveland Clinic researchers elected as AAAS Fellows for excellent contributions to science

Cleveland Clinic researchers Richard A. Padgett, Ph.D., and Edward F. Plow, Ph.D., have been named Fellows of the American Association for the Advancement of Science (AAAS). This year's AAAS Fellows will be formally announced in the AAAS News & Notes section of the journal Science on Nov. 29, 2013.

26 Nov 2013

MO BIO Laboratories announces launch of PowerClean Pro DNA and RNA Clean-Up Kits

MO BIO Laboratories, Inc., the leader in microbial, stool, plant, and soil nucleic acid purification, announces the launch of the PowerClean Pro DNA and RNA Clean-Up Kits, featuring a fast, 7 minute protocol for removal of amplification inhibitors including humic substances, polysaccharides, polyphenolics, heme, and lipids from purified DNA or RNA.

20 Nov 2013

New 4th generation HIV assays now available to improve screening for HIV infection

Laboratory Corporation of America Holdings announced today the availability of a 4th generation HIV antigen/antibody combination assay and a new diagnostic algorithm that improves screening for HIV infection.

6 Nov 2013

New type of antibiotic kills multidrug-resistant germ common to health care settings

A new type of antibiotic called a PPMO, which works by blocking genes essential for bacterial reproduction, successfully killed a multidrug-resistant germ common to health care settings, UT Southwestern Medical Center researchers report.

16 Oct 2013

MO BIO Laboratories introduces UltraClean-htp 96 Well Swab DNA Kit

MO BIO Laboratories, Inc., the leader in microbial, stool, plant, and soil nucleic acid purification, announces the launch of the UltraClean-htp 96 Well Swab DNA Kit. The kit is designed for rapid mechanical lysis of microbial cells from low biomass and low inhibitor containing swabs, paper or filter paper for direct application to PCR for metagenomic analysis.

2 Oct 2013

Enzymatics Acquires Archerdx For Up To $50M

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6 Sep 2013

New method to detect genetic variations that initiate colon cancer

A new, highly sensitive method to detect genetic variations that initiate colon cancer could be readily used for noninvasive colon cancer screening, according to a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research.

4 Sep 2013

Nanostructures made of DNA strands can encapsulate, release small-molecule drugs

Nanoscale "cages" made from strands of DNA can encapsulate small-molecule drugs and release them in response to a specific stimulus, McGill University researchers report in a new study.

2 Sep 2013

Researchers discover role played by epigenetic factors in senescence and age-related diseases

One way cells promote tumor suppression is through a process called senescence, an irreversible arrest of proliferation. Senescence is thought to be associated with normal aging, but is also a protective measure by the body against run-away cell replication.

31 Aug 2013

Novel machine learning-based approach used to predict hepatotoxic potential of DNA drug

New classes of therapeutic antisense oligonucleotides can have toxic effects on the liver. A novel machine learning-based approach used to predict the hepatotoxic potential of an antisense drug based on its chemical sequence is presented in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers.

28 Aug 2013

Scientists prove 50-year-old hypothesis of RNA 'higher-order' structure

When Francis Crick and James Watson discovered the double helical structure of deoxyribonucleic acid (DNA) in 1953, it began a genetic revolution to map, study, and sequence the building blocks of living organisms.

27 Aug 2013

Nucleic Acid News and Research

Eurofins Medigenomix, Orion Diagnostica Oy sign co-exclusive technology license agreement

Study: Antisense drugs show activity in wide range of tissues and organs

Gene Expression Barcode 3.0 tool proves to be a vital resource for cancer research

New assay allows rapid and sensitive detection of Chlamydia trachomatis

Pronai Therapeutics reports positive results from PNT2258 Phase II study on lymphoma

Johns Hopkins researchers discover some cases of scleroderma likely to be initiated by cancer

PrimeraDx gets FDA clearance for ICEPlex C. difficile Assay Kit and ICEPlex System

Bruker receives FDA clearance to market MALDI Biotyper CA System in the U.S.

Seed grants support cancer diagnosis and treatment, vascular health research

Cleveland Clinic researchers elected as AAAS Fellows for excellent contributions to science

MO BIO Laboratories announces launch of PowerClean Pro DNA and RNA Clean-Up Kits

New 4th generation HIV assays now available to improve screening for HIV infection

New type of antibiotic kills multidrug-resistant germ common to health care settings

MO BIO Laboratories introduces UltraClean-htp 96 Well Swab DNA Kit

Enzymatics Acquires Archerdx For Up To $50M

New method to detect genetic variations that initiate colon cancer

Nanostructures made of DNA strands can encapsulate, release small-molecule drugs

Researchers discover role played by epigenetic factors in senescence and age-related diseases

Novel machine learning-based approach used to predict hepatotoxic potential of DNA drug

Scientists prove 50-year-old hypothesis of RNA 'higher-order' structure

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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