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Researchers identify a druggable copper-signaling pathway that drives inflammation

Inflammation is a complex biological process that can eradicate pathogens and promotes repair of damaged tissues.

27 Apr 2023

UC-led research team receives NIH grant to study the role of an enzyme in lysosome function

Once thought of as having one simple job within cells, researchers continue to learn more about the importance of organelles called lysosomes.

11 Apr 2023

Chemists discover novel, highly effective anticancer agents with tridimensional structures

A research team co-led by chemists from City University of Hong Kong recently discovered novel, highly effective anticancer agents with tridimensional structures, which have high anticancer activity, low toxicity and the ability to overcome drug resistance in cancer cells.

7 Apr 2023

CrestOptics launches CICERO system to provide all-in-one solution for widefield and spinning disk confocal microscopy

CrestOptics S.p.A., a manufacturer of high-end microscopy solutions and advanced systems for fluorescence microscopy and diagnostic applications, today announced the launch of its new spinning disk confocal microscope system, CICERO.

From CrestOptics 3 Apr 2023

FDA-approved drug keeps light-sensitive photoreceptors alive in lab models of LCA 10

A National Institutes of Health team has identified a compound already approved by the U.S. Food and Drug Administration that keeps light-sensitive photoreceptors alive in three models of Leber congenital amaurosis type 10 (LCA 10), an inherited retinal ciliopathy disease that often results in severe visual impairment or blindness in early childhood.

29 Mar 2023

Researchers discover a new role for one of the genes linked to hereditary spastic paraplegia

Researchers from the University of Seville and the Seville Institute of Biomedicine (IBiS), in collaboration with the University of Cambridge, have identified a new role for one of the genes related to hereditary spastic paraplegia.

27 Mar 2023

New technology can rapidly analyze the metabolic state of lipids in cells

Professor Itaru Hamachi, Lecturer Tomonori Tamura, and Assistant Professor Masaki Tsuchiya of Kyoto University have developed a new technology called O-ClickFC (Organelle-selective click labeling with flow cytometry), which can, at a very high speed, analyze the metabolic state of lipids in cells.

27 Mar 2023

Cryo-EM provides structural insights into a specific protein involved in Hailey-Hailey disease

Hailey-Hailey disease is a rare, inherited condition characterized by patches of blisters appearing mainly in the skin folds of the arm pits, groin and under the breasts.

24 Mar 2023

Keeping stem cells clean and tidy is an integral step to promoting a long healthspan

In humanity's ongoing quest for the elixir of life, the science keeps pointing to stem cells. Research increasingly shows that maintaining stem cell fitness promotes a long healthspan, and new findings show keeping stem cells clean and tidy is an integral step.

21 Mar 2023

Newly identified therapeutic target could lead to more effective treatment of glaucoma

Indiana University School of Medicine researchers have identified a new therapeutic target that could lead to more effective treatment of glaucoma.

10 Mar 2023

Centrosome regulates nerve cell migration, study finds

Researchers from the DZNE have solved an important puzzle in neurobiology: the wiring and the movement of nerve cells are interwoven, but separately controlled.

15 Feb 2023

Study reveals some of the fundamental biology of p97 protein in neurodegenerative disease

The p97 protein is one of your body's best garbage disposers. It floats around in your cells looking for signals that a protein is past its shelf life and needs to be trashed.

7 Feb 2023

Study: FER1L5 protein essential for sperm to undergo acrosome reaction and male fertility

Fertilization is the union of two cells: an egg and a sperm. Before the egg and the sperm fuse, an event known as the "acrosome reaction" needs to occur in the sperm.

25 Jan 2023

Targeting newly discovered signaling pathway could boost the potency of cancer therapeutics

Cells zealously protect the integrity of their genomes, because damage can lead to cancer or cell death. The genome -; a cell's complete set of DNA -; is most vulnerable while it is being duplicated before a cell divides. Cancer cells constantly are dividing, so their genomes are constantly in jeopardy.

24 Jan 2023

Organelle News and Research

Researchers identify a druggable copper-signaling pathway that drives inflammation

UC-led research team receives NIH grant to study the role of an enzyme in lysosome function

Chemists discover novel, highly effective anticancer agents with tridimensional structures

CrestOptics launches CICERO system to provide all-in-one solution for widefield and spinning disk confocal microscopy

FDA-approved drug keeps light-sensitive photoreceptors alive in lab models of LCA 10

Researchers discover a new role for one of the genes linked to hereditary spastic paraplegia

New technology can rapidly analyze the metabolic state of lipids in cells

Cryo-EM provides structural insights into a specific protein involved in Hailey-Hailey disease

Keeping stem cells clean and tidy is an integral step to promoting a long healthspan

Newly identified therapeutic target could lead to more effective treatment of glaucoma

Centrosome regulates nerve cell migration, study finds

Study reveals some of the fundamental biology of p97 protein in neurodegenerative disease

Study: FER1L5 protein essential for sperm to undergo acrosome reaction and male fertility

Targeting newly discovered signaling pathway could boost the potency of cancer therapeutics

Study identifies LAP1 as a master regulator of nuclear envelope remodeling during melanoma progression

Researchers discover new cellular component with importance for the sense of smell

Bioorthogonal system for targeted release of nitrite ions into cancer cells

Nerve cell discovery may improve treatment options for patients with neurodegenerative diseases

Researchers identify a new gene implicated in rare lysosomal storage disorder

New research model enables scientists to test therapeutics for rare neurodegenerative diseases

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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