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The truth about chocolate: does it really contain flavonoids?

There have been many news stories over the years about chocolate and whether it is good or bad for you. The stories often comment on a chemical constituent of chocolate: flavonoids. But what are flavonoids? Does chocolate even contain them? And why should we care if it does?

18 May 2012

Spectrum initiates ZEVALIN and MGd Phase 2 combination study in NHL

Spectrum Pharmaceuticals, a biotechnology company with fully integrated commercial and drug development operations with a primary focus in hematology and oncology, today announced the initiation of a Phase 2 study evaluating ZEVALIN (ibritumomab tiuxetan) Injection for intravenous use + rituximab in combination with motexafin gadolinium (MGd) in patients with rituximab-refractory low-grade or follicular B-cell non-Hodgkin's lymphoma.

18 May 2012

Fitness fanatic dad becomes research pioneer after kidney disease diagnosis

A super-fit father who rowed the distance from the Equator to the North Pole on a rowing machine has told of how his experience of kidney disease led to him becoming the first patient to take part in a groundbreaking research study run in Sheffield and Leeds.

17 May 2012

Healthy lifestyle choices may reduce risk of stroke

Every 40 seconds someone in the United States has a stroke. Stroke is the fourth leading cause of death and the number one cause of adult disability in the country. While stroke often occurs without warning, understanding risk factors and learning to recognize symptoms can potentially save lives and limit damage if a stroke occurs. In recognition of National Stroke Awareness Month, Northwestern Medicine experts encourage consumers learn about their potential risk factors and start making lifestyle decisions that may decrease their likelihood of having a stroke.

16 May 2012

Asymptomatic patients can benefit from ExE after coronary revascularization

Asymptomatic patients who undergo treadmill exercise echocardiography (ExE) after coronary revascularization may be identified as being at high risk but those patients do not appear to have more favorable outcomes with repeated revascularization, according to a report published Online First by Archives of Internal Medicine, a JAMA Network publication. The article is part of the journal's Less is More series.

15 May 2012

FDA clears MAQUET's new MEGA larger volume intra-aortic balloon catheters

MAQUET Cardiovascular LLC, a leading provider of cardiovascular technologies, today announced that it has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for its new MEGA 7.5Fr. 30cc and 40cc intra-aortic balloon (IAB) catheters. These new, larger volume catheters will allow clinicians to provide patients with greater hemodynamic support, regardless of their height.

14 May 2012

Naked mole rat's proteasome assemblies differ in composition from other short-lived rodents

The naked mole rat, a curiously strange, hairless rodent, lives many years longer than any other mouse or rat. Scientists at The University of Texas Health Science Center San Antonio's Barshop Institute of Longevity and Aging Studies continue to explore this mystery.

14 May 2012

EO2 Concepts added to Marathon Medical's FSS contract

Electrochemical Oxygen Concepts, the developer of a unique and innovative chronic wound treatment device, announced it has been added to Marathon Medical's existing Federal Supply Schedule (FSS) contract, administered by The Department of Veterans Affairs.

11 May 2012

Prototype device would help obese patients breathe during medical procedures

The best doctors strive to relieve their patients' burdens. A physician in Houston asked Rice University students to help him do so in the most literal way. A team of bioengineering seniors built a prototype device to literally lift the weight from obese patients who, while undergoing surgical procedures, might otherwise have trouble breathing.

10 May 2012

New approach to advance quality of pregnancy monitoring

The University of California, San Diego Jacobs School of Engineering announced today that it is a Grand Challenges Explorations winner, an initiative funded by the Bill & Melinda Gates Foundation. Bioengineering Professor Todd Coleman, in collaboration with Materials Science and Engineering Professor John A. Rogers at the University of Illinois at Urbana-Champaign, will pursue an innovative global health and development research project, titled "Epidermal Electronics for Continuous Pregnancy Monitoring."

10 May 2012

LWW wins 21 awards in 15 categories from ASHPE

Lippincott Williams & Wilkins (LWW), part of Wolters Kluwer Health, is pleased to announce that it has won 21 awards in 15 categories, which is a record number of wins in a single year for LWW overall. ASHPE's 12th annual awards competition recognizes member articles and publications for editorial, design, print, and online award categories.

10 May 2012

Dehaier Medical first quarter revenues increase 12.3% to $3.3 million

Dehaier Medical Systems Ltd., an emerging leader in the development, assembly, marketing and sale of medical devices and homecare medical products, today announced its financial results for its first quarter ended March 31, 2012.

10 May 2012

MSU researcher wins Grand Challenges Explorations grant for work on TB

For his work on developing new treatments for tuberculosis, a Michigan State University researcher has been named a Grand Challenges Explorations winner, an initiative funded by the Bill & Melinda Gates Foundation.

10 May 2012

Free whooping cough vaccine cut concerns experts

Heath experts are concerned that parents and carers of newborn babies will stop getting the whooping cough vaccine after the state government cut its free immunisation program in the midst of a fatal epidemic.

9 May 2012

UMD researchers design molecular container that can increase solubility of drugs

A cross-disciplinary team of researchers at the University of Maryland has designed a molecular container that can hold drug molecules and increase their solubility, in one case up to nearly 3000 times. Their discovery opens the possibility of rehabilitating drug candidates that were insufficiently soluble. It also offers an opportunity to improve successful drugs that could be made even better with better solubility.

9 May 2012

Viewpoints: Taking aim at 'superbugs'; Friending organ donations; Ariz. and Kansas abortion efforts hurt women

In the battle between humans and infectious bacteria, humans have had the advantage, at least since antibiotics were introduced into our arsenal 70 or so years ago. Now, however, our weapons appear to be turning against us as germs have found ways to outfox antibiotics…. A second challenge is to keep a steady stream of new antibiotics in the pipeline, and this is where the big pharmaceutical companies based in Europe and the U.S. come in….

9 May 2012

New process cells use to produce proteins in low-oxygen environments

"How do bodily cells function when we are at a high altitude where the air contains little oxygen?"

7 May 2012

Researchers make white fat take on characteristics of brown fat

Brown seems to be the color of choice when it comes to the types of fat cells in our bodies. Brown fat expends energy, while its counterpart, white fat stores it. The danger in white fat cells, along with the increased risk for diabetes and heart disease it poses, seems especially linked to visceral fat. Visceral fat is the build-up of fat around the organs in the belly.

7 May 2012

Researchers identify new mechanism that causes choroidal neovascularization

Sloppy shipping of a donated human retina to an Indiana University researcher studying a leading cause of vision loss has inadvertently helped uncover a previously undetected mechanism causing the disease. The discovery has led researchers to urge review of how millions of dollars are spent investigating the cause of a type of age-related macular degeneration called choroidal neovascularization.

5 May 2012

PDE4 enzyme regulates division of tumour cells and blood vessel growth in cancer tissue

Lung cancer is the leading cause of cancer death throughout the world. Standard treatment methods do not usually result in long-term recovery. In addition to the proliferation of the tumour cells, the growth of blood vessels controls tumors development. The blood vessel growth is controlled by several signalling molecules. Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim and Justus Liebig University Giessen have discovered a molecule that plays a key role in this process. They succeeded in reducing tumour growth in their experiments by blocking the phosphodiesterase PDE4.

5 May 2012