Oxygen News and Research

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Low oxygen levels in prostate tumors can predict recurrence

Fox Chase Cancer Center researchers have discovered that low-oxygen regions in prostate tumors can be used to predict a rise in prostate-specific antigen (PSA) levels, a marker of tumor recurrence in prostate cancer.

17 May 2009

New device could track tumor's growth

Surgical removal of a tissue sample is now the standard for diagnosing cancer. Such procedures, known as biopsies, are accurate but only offer a snapshot of the tumor at a single moment in time.

13 May 2009

Diet rich in nuts and olive oil protects against age-related macular degeneration

New research has found that a diet which is low in trans fats and regularly includes nuts, olive oil and other foods containing omega-three fatty acids appears to offer some protection from the eye disease age-related macular degeneration (AMD).

13 May 2009

Schering-Plough starts patient enrollment in phase 3 trial for Acadesine

Schering-Plough Corporation today announced the start of patient enrollment in RED-CABG, the Phase 3 Trial for acadesine, an investigational, potentially first-in-class adenosine regulating agent (ARA). Acadesine was licensed from PeriCor Therapeutics, Inc., a privately held specialty biopharmaceutical company.

12 May 2009

Oxidation of potassium channel in cells linked to loss of neuronal function in aging

Researchers at UMDNJ-Robert Wood Johnson Medical School are one step closer to determining how human cells can be protected against the affects of age-related neurodegeneration including Alzheimer's and Parkinson's disease.

12 May 2009

Omega-three fatty acid rich foods lower risk for eye disease

Regularly eating fish, nuts, olive oil and other foods containing omega-three fatty acids and avoiding trans fats appears to be associated with a lower risk for the eye disease age-related macular degeneration, according to two reports in the May issue of Archives of Ophthalmology.

12 May 2009

Smoking makes it harder for brain blood flow to recover from long-term heavy drinking

Alcohol-use disorders (AUDs) can damage the brain, particularly the frontal and parietal cortices, although this damage is at least partially reversible with sustained abstinence from alcohol. Chronic smoking is extremely common among individuals with AUDs.

12 May 2009

Building a bridge from Alzheimer's disease to diabetes and vice versa

Modern societies face the increasing burden of age-related diseases, in particular Alzheimer's disease (AD) and type 2 diabetes (T2D).

12 May 2009

Discovery of major new treatment target in diseased arteries

Removing a single protein prevents early damage in blood vessels from triggering a later-stage, frequently lethal complication of atherosclerosis, according to research published online today in the journal Nature Medicine. By eliminating the gene for a signaling protein called cyclophilin A (CypA) from a strain of mice, researchers were able to provide complete protection against abdominal aortic aneurysm (AAA).

11 May 2009

New understanding on mechanisms of early stage liver reperfusion injury

Reperfusion of a previously ischemic tissue is associated with additional injury leading to structural and functional alterations in many organs including the liver.

7 May 2009

Sufferers of mild to moderate obstructive sleep apnea may benefit from exercise

Practicing certain tongue and pharyngeal exercises may reduce symptoms of mild to moderate obstructive sleep apnea (OSA), according to new research being published in the second issue for May of the American Journal of Respiratory and Critical Care Medicine.

7 May 2009

Neuroglobin making gene tied to Alzheimer's

Of dozens of candidates potentially involved in increasing a person's risk for the most common type of Alzheimer's disease that affects more than 5 million Americans over the age of 65, one gene that keeps grabbing Johns Hopkins researchers' attention makes a protein called neuroglobin.

6 May 2009

Even mildly premature infants have increased risk of medically attended respiratory syncytial virus infection

Even mildly premature infants (gestational ages of 33 weeks through 36 weeks) have an increased risk of medically attended respiratory syncytial virus infection, which is the leading cause of lower respiratory tract infection in infants and young children and can lead to pneumonia in babies, according to a Kaiser Permanente Division of Research study.

5 May 2009

Protein kinase JNK1 identified as treatment target for retinopathy in premature babies

Results of a study in mice by researchers at the University of California, San Diego strongly suggest that the protein kinase JNK1 plays a key role in the development of retinopathy in premature infants.

4 May 2009

Iron deficiency in womb may delay auditory nervous system in preemies

Iron plays a large role in brain development in the womb, and new University of Rochester Medical Center research shows an iron deficiency may delay the development of auditory nervous system in preemies. This delay could affect babies ability to process sound which is critical for later language development in early childhood.

4 May 2009

Cigarette smoke exposure may lower levels of antioxidants in kids

Children exposed to cigarette smoke have lower levels of antioxidants, which help the body defend itself against many biological stresses.

4 May 2009

Obstructive sleep apnea increases risk of heart and vascular disease

Obstructive sleep apnea, or periodic interruptions in breathing throughout the night, thickens sufferers' blood vessels. Moreover, it increases the risk of several forms of heart and vascular disease.

4 May 2009

Novel "lab on a tube" monitoring device

The need for improved monitoring of neurotrauma patients has resulted in the development of a prototype of a novel, multitasking "lab on a tube" at the University of Cincinnati (UC).

4 May 2009

A systems biology map of iron metabolism

Scientists at the Wake Forest University School of Medicine, the University of Manchester in the United Kingdom, and the Virginia Bioinformatics Institute at Virginia Tech have taken the first steps toward constructing a systems biology map of iron metabolism.

30 Apr 2009

Safely transporting a preterm or low birth weight infant

New guidelines from the American Academy of Pediatrics should eliminate one of the many stresses of bringing a preterm or low birth weight infant home from the hospital.

27 Apr 2009