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National Institute for Health and Clinical Excellence (NICE) releases appraisal consultation document on treatment of pulmonary arterial hypertension in adults

The National Institute for Clinical Excellence (NICE) has published on its website the preliminary recommendations of its Appraisal Committee on the use of epoprostenol, iloprost, bosentan, sitaxentan and sildenafil for the treatment of pulmonary hypertension in adults.

3 Mar 2008

Researchers investigate predictors for sickle-cell-anemia complications

Researchers at UT Southwestern Medical Center have determined that the level, or saturation, of oxygen in blood could be used to identify children with sickle cell anemia who are at an increased risk of stroke.

1 Mar 2008

Potential novel class of drugs for treating heart attacks and stroke

A new compound that blocks an early step in cell death could lead to a novel class of drugs for treating heart attacks and stroke.

28 Feb 2008

Using microorganisms to remove trichloroethene from water

In 2002, Bruce Rittmann, PhD, director of the Biodesign Institute's Center for Environmental Biotechnology, received a patent for an innovative way to use nature to lend society a hand.

28 Feb 2008

Low-intensity exercise reduces fatigue symptoms by 65 percent

Sedentary people who regularly complain of fatigue can increase their energy levels by 20 percent and decrease their fatigue by 65 percent by engaging in regular, low intensity exercise, according to a new University of Georgia study.

28 Feb 2008

Discovery of potential drug targets for sepsis

"We have identified a key connection of signaling pathways in the cascade of events leading to sepsis. This defines a crucial point where the immune system spirals out of control to cause severe sepsis and where there is an opportunity for therapeutic intervention," says Scripps Research Professor Wolfram Ruf, who led the research with his postdoctoral fellow Frank Niessen.

28 Feb 2008

New vaccine technology decreases E. coli in beef cattle

Despite millions of dollars spent on food safety research over the last 10 years, ground beef recalls due to E. coli O157:H7 were higher in 2007 than in 2006, according to researchers from Kansas State University and West Texas A&M University. E. coli O157:H7 has been linked to foodborne illnesses in humans after consuming contaminated beef and produce.

28 Feb 2008

Hormones produced by the heart eliminate pancreatic cancer in mice

Hormones produced by the heart eliminated human pancreatic cancer in more than three-quarters of the mice treated with the hormones and eliminated human breast cancer in two-thirds of the mice, according to researcher David Vesely, a doctor at the James A. Haley Veterans Hospital in Tampa and a professor at the University of South Florida (USF).

27 Feb 2008

You are what you eat and drink - and that is recorded in your hair

University of Utah scientists developed a new crime-fighting tool by showing that human hair reveals the general location where a person drank water, helping police track past movements of criminal suspects or unidentified murder victims.

27 Feb 2008

2 oxygenation events in ancient oceans sparked spread of complex life

The rise of oxygen and the oxidation of deep oceans between 635 and 551 million years ago may have had an impact on the increase and spread of the earliest complex life, including animals, according to a study reported in the Proceedings of the National Academy of Sciences online Early Edition during the week of February 25 – 29.

26 Feb 2008

Obese children experience more problems during surgery

A new study from the University of Michigan Health System finds that obese children are much more likely than normal-weight children to have problems with airway obstruction and other breathing-related functions during surgery

26 Feb 2008

Childhood obesity leads to higher rate of problems during surgery

Add this to the growing list of health challenges faced by obese children: A new study from the University of Michigan Health System finds that obese children are much more likely than normal-weight children to have problems with airway obstruction and other breathing-related functions during surgery.

25 Feb 2008

Genetic defect causes immune deficiency and balance disorder

A genetic defect that causes a severe immune deficiency in humans may also produce balance disorders, according to a new study by researchers at the University of Iowa, The Jackson Laboratory and East Carolina University.

21 Feb 2008

Study identifies another strategy for normalizing tumor blood supply

Manipulating levels of nitric oxide (NO), a gas involved in many biological processes, may improve the disorganized network of blood vessels supplying tumors, potentially improving the effectiveness of radiation and chemotherapy.

21 Feb 2008

Discovery of gene expression pathway that influences process of oxidative stress

The same chemical reaction that causes iron to rust plays a similarly corrosive role in our bodies.

21 Feb 2008

New way to grow blood vessels

Researchers at Dana-Farber Cancer Institute have found a previously unknown molecular pathway in mice that spurs the growth of new blood vessels when body parts are jeopardized by poor circulation.

21 Feb 2008

New techniques for detecting blood clots/air bubbles in arteries

New techniques for detecting emboli (harmful blood clots/air bubbles in arteries) developed at the University of Leicester have played a major role in dramatically reducing stroke rates after carotid endarterectomy.

20 Feb 2008

U-M scientists develop tool to probe role of oxidative stress in aging, disease

Oxygen, although essential for human life, can turn into an aggressive chemical that is outright toxic to important molecules inside our cells.

18 Feb 2008

Cholesterol-lowering drug used to block staph infections in mince

An international team of researchers supported by the National Institutes of Health (NIH) has blocked staph infections in mice using a drug previously tested in clinical trials as a cholesterol-lowering agent.

17 Feb 2008

Metabolic syndrome linked to climate

Researchers from the University of Chicago have discovered that many of the genetic variations that have enabled human populations to tolerate colder climates may also affect their susceptibility to metabolic syndrome, a cluster of related abnormalities such as obesity, elevated cholesterol levels, heart disease, and diabetes.

17 Feb 2008