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Proteins Nox1 and Nox2 play important role in amyotrophic lateral sclerosis

University of Iowa researchers investigating the basic biology of cell signaling have made a discovery that may have therapeutic implications for amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases.

13 Sep 2007

Effects of diesel exhaust on heart and blood vessel function

Air pollution could be putting patients with heart disease at risk by affecting blood vessels and clotting, researchers warn

13 Sep 2007

Potential new drug target for preventing postmenopausal bone loss

Scientists have discovered new information about an immune pathway in mice that explains how oxidative stress that results from acute estrogen deficiency leads to the loss of bone.

11 Sep 2007

Organisms found on contact lenses provide clues to corneal eye infections

Cultures of contact lenses may sometimes identify the organisms involved in cases of corneal eye infection, according to a report in the September issue of Archives of Ophthalmology, one of the JAMA/Archives journals.

11 Sep 2007

Yellow plant pigments may lower risk for age-related eye disease

Consuming higher levels of the yellow plant pigments lutein and zeaxanthin may be associated with a lower risk for age-related macular degeneration, according to a report in the September issue of Archives of Ophthalmology, one of the JAMA/Archives journals.

11 Sep 2007

Scientists identify process that causes blood vessels to constrict during and after a heart attack

They've also demonstrated that delivering a vital molecule that is depleted during this process directly to those blood vessels can reverse damage and help restore blood flow.

11 Sep 2007

Vitamin C inhibits the growth of some tumors

Nearly 30 years after Nobel laureate Linus Pauling famously and controversially suggested that vitamin C supplements can prevent cancer, a team of Johns Hopkins scientists have shown that in mice at least, vitamin C - and potentially other antioxidants - can indeed inhibit the growth of some tumors ¯ just not in the manner suggested by years of investigation.

11 Sep 2007

A chink in bacteria's armor

Biomedical researchers at Boston University's College of Engineering may have discovered the path toward developing better drugs capable of defeating so-called “superbugs,” bacteria that have developed resistance to common antibiotics. The researchers have discovered a previously unknown chain of events occurring in bacteria that opens to door to new avenues of research.

10 Sep 2007

Avocado extract stops growth of pre-cancerous cells that lead to oral cancer

Nutrients taken from avocados are able to thwart oral cancer cells, killing some and preventing pre-cancerous cells from developing into actual cancers, according to researchers at Ohio State University.

5 Sep 2007

N-acetylcysteine may not be as safe as once thought

Certain preparations taken to enhance athletic performance or stave off disease contain an anti-oxidant that could cause harm.

5 Sep 2007

Fat in the stomach may actually cause vitamin C to promote formation of cancer causing chemicals

The researchers analysed the impact of both fat (lipid) and vitamin C (ascorbic acid) on nitrite chemistry in the upper (proximal) stomach, which is especially vulnerable to pre-cancerous changes and tumour growth.

4 Sep 2007

Fat: An active player in the regulation of many processes in health and disease

Why should we be interested in doing obesity-related research? Emphasis is put on this type of research simply because of the fact that the epidemiological data and predictions are alarming. Worldwide it is estimated that one person in every eight is overweight and more than 300 millions are obese

3 Sep 2007

Patent foramen ovale (PFO) and atrial septal defect (ASD) closure

A PFO and an ASD are congenital structural heart diseases characterized by a communication between heart chambers at the level of the wall (septum) separating them. These chambers are the left and right atrium as shown on the picture below. The right atrium receives (dark) oxygen-depleted blood from the great veins, while the left atrium receives (red) oxygen-rich blood from the lungs.

3 Sep 2007

Blood-flow detector software shows promise in preventing brain damage

Researchers from the Johns Hopkins Children's Center and Cambridge University in England have designed an automated means of continuously tracking potentially dangerous changes in blood flow to the brain in real time, a system that shows promise for preventing brain damage and death in children with head injuries.

3 Sep 2007

Efficacy of non-invasive ventilation in patients with acute cardiogenic pulmonary oede

Acute cardiogenic pulmonary oedema, or "fluid on the lung", is a common, extremely distressing and often fatal condition that is a major consumer of health care resources. The aim of the 3CPO trial was to establish whether high-pressure oxygen, given by a simple facemask, could help reduce the death rate in patients with this condition.

2 Sep 2007

Does physical activity provide a molecular key to longevity?

Fitness and physical exercise are among the most neglected means to improve prognosis. They are the healthiest cardiovascular intervention. Even cardiologists focus on pharmacological treatment and evaluate classical risk factors without asking about daily exercise or objective measures of physical capacity. It is surprising considering the strong data that underscores the survival benefit of regular exercise training.

2 Sep 2007