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TSRI researchers solve structure of key protein in deadly, but little known virus

What began as a summer internship project designed for an undergraduate student evolved into a one-year study of one of the deadliest, but little known viruses. Researchers at The Scripps Research Institute (TSRI) have now solved the structure of a key protein in the Nipah virus, which could pave the way for the development of a much-needed antiviral drug.

20 Nov 2013

Researchers use computer modeling to investigate complex relationships between spread and evolution of HIV virus

Researchers at Los Alamos National Laboratory are investigating the complex relationships between the spread of the HIV virus in a population (epidemiology) and the actual, rapid evolution of the virus (phylogenetics) within each patient's body.

20 Nov 2013

Study shows bacteria can passively integrate damaged DNA in their own genome

From a bacteria's perspective the environment is one big DNA waste yard. Researchers have now shown that bacteria can take up small as well as large pieces of old DNA from this scrapheap and include it in their own genome.

20 Nov 2013

Mutations affecting immune system play important role in breast cancer

Mutations in the genes that defend the body against cancer-related viruses and other infections may play a larger role in breast cancer than previously thought, according to a study at the University of Illinois at Chicago.

19 Nov 2013

Entire structure of health-care delivery needs to be re-engineered to address threat of antibiotic resistance

The entire structure of health-care delivery for effective antibiotics – from research and development, to distribution and rational use – needs to be re-engineered to address the looming global threat of antibiotic resistance, say the authors of a new report, published today [Sunday 17 November] in The Lancet Infectious Diseases, ahead of European Antibiotic Awareness Day, and the US Centers for Disease Control and Prevention (CDC) ‘Get Smart About Antibiotics Week’ on Monday 18 November.

18 Nov 2013

Researchers solve structure of key protein in Nipah virus

What began as a summer internship project designed for an undergraduate student evolved into a one-year study of one of the deadliest, but little known viruses.

18 Nov 2013

Concordia University professors use funds to fight fungus and update aircraft

Thanks to new funding from the Government of Canada, two Concordia University professors just might create a greener aerospace industry and help cure fungal infections.

16 Nov 2013

Small molecule compound shows significant success in controlling polyomaviruses

A team of scientists reports that a small molecule compound showed significant success in controlling the infectivity and spread of three polyomaviruses in human cell cultures. To date there has been no medicine approved to treat such viruses, which prey on transplant recipients, people with HIV, and others whose immune systems have been weakened.

15 Nov 2013

TAILORED-Treatment project to increase effectiveness of antibiotics receives EU funding

The European Union has funded a 4 year project called TAILORED-Treatment with € 6.000.000,-. The main goal of TAILORED -Treatment is to establish a strategy that can be used to increase the effectiveness of antibiotic treatment, reduce any potential side-effects of therapy, and help limit the emergence of antimicrobial resistance in hospitalized children and adults. The project will be coordinated by Erasmus MC, Rotterdam, the Netherlands.

14 Nov 2013

Infection prevention: an interview with Dr. Robert Gorab, Chief Medical Officer, Hoag Orthopedic Institute

HOI has one of the lowest if not the lowest surgical readmission rate in the State of California. Our all-cause readmission rate is 3.3% and our joint replacement readmission was at 1.8% based on published CMS reports we received in September 2013.

12 Nov 2013

Australian scientists unravel mystery behind immune system memory

While the principle of immune memory has been known for decades, the exact molecular mechanisms underpinning it have remained a mystery. Australian scientists have now unraveled part of that mystery, identifying the role of a gene called STAT3, which acts as a kind of roundabout, directing chemical messenger molecules to various destinations.

12 Nov 2013

PDL BioPharma closes financing transaction with Durata Therapeutics

PDL BioPharma, Inc. announced today that it closed a financing transaction with Durata Therapeutics, Inc., a pharmaceutical company focused on the development and commercialization of novel therapeutics for patients with infectious diseases and acute illnesses.

6 Nov 2013

Researchers on the way to find cure against African sleeping sickness

Researchers at Umeå University have identified drugs targeting infections of the parasite Trypanosoma brucei and are thereby well on the way to find a cure against African sleeping sickness. This is the kernel of a thesis, which will be publicly defended on 8 November 2013.

6 Nov 2013

Research: Chronic stress changes gene activity in immune cells before reaching bloodstream

New research shows that chronic stress changes gene activity in immune cells before they reach the bloodstream. With these changes, the cells are primed to fight an infection or trauma that doesn't actually exist, leading to an overabundance of the inflammation that is linked to many health problems.

6 Nov 2013

AMP 2013 to focus on genomics, proteomics, informatics, reimbursement and optimization of patient care

AMP will host its largest ever annual meeting next week with an expected attendance of more than 1,700 molecular diagnostic professionals plus 1,300 representatives from more than 180 exhibiting companies. With more than 25 hours of educational sessions and 350 poster presentations, the AMP 2013 Annual Meeting is the premier source for educational information on all things molecular.

5 Nov 2013

Biothera announces top-line results from Phase 2b clinical trial in non-small cell lung cancer

Biothera announced today top-line results from its Phase 2b clinical trial in non-small cell lung cancer (NSCLC) that evaluated its immunotherapeutic drug candidate, Imprime PGG®, with cetuximab (Erbitux®), carboplatin and paclitaxel compared with the monoclonal antibody and chemotherapy combination alone.

5 Nov 2013

Probiotics may help keep bad germs at bay

Microbes are everywhere - thousands of species are in your mouth, and thousands are in a glass of tap water. The ones in your mouth are mostly harmless - as long as you brush and floss so they don't form a biofilm that allows gum disease a path into the blood stream.

4 Nov 2013

EcoHealth Alliance discovers new SARS-like coronavirus in Chinese horseshoe bats

EcoHealth Alliance, a nonprofit organization that focuses on local conservation and global health issues, announced the discovery of a new SARS-like coronavirus (CoV) in Chinese horseshoe bats.

31 Oct 2013

EPFL and UNIL-CHUV scientists create first map of human HIV resistance

The key to future HIV treatment could be hidden right in our own genes. Everyone who becomes infected deploys defense strategies, and some even manage to hold the virus at bay without any therapy at all.

29 Oct 2013

Researchers identify agricultural management practices that can reduce contamination risk in produce

Researchers from Cornell University have identified some agricultural management practices in the field that can either boost or reduce the risk of contamination in produce from two major foodborne pathogens: salmonella, the biggest single killer among the foodborne microbes, and Listeria monocytogenes.

22 Oct 2013

Pathogen News and Research

TSRI researchers solve structure of key protein in deadly, but little known virus

Researchers use computer modeling to investigate complex relationships between spread and evolution of HIV virus

Study shows bacteria can passively integrate damaged DNA in their own genome

Mutations affecting immune system play important role in breast cancer

Entire structure of health-care delivery needs to be re-engineered to address threat of antibiotic resistance

Researchers solve structure of key protein in Nipah virus

Concordia University professors use funds to fight fungus and update aircraft

Small molecule compound shows significant success in controlling polyomaviruses

TAILORED-Treatment project to increase effectiveness of antibiotics receives EU funding

Infection prevention: an interview with Dr. Robert Gorab, Chief Medical Officer, Hoag Orthopedic Institute

Australian scientists unravel mystery behind immune system memory

PDL BioPharma closes financing transaction with Durata Therapeutics

Researchers on the way to find cure against African sleeping sickness

Research: Chronic stress changes gene activity in immune cells before reaching bloodstream

AMP 2013 to focus on genomics, proteomics, informatics, reimbursement and optimization of patient care

Biothera announces top-line results from Phase 2b clinical trial in non-small cell lung cancer

Probiotics may help keep bad germs at bay

EcoHealth Alliance discovers new SARS-like coronavirus in Chinese horseshoe bats

EPFL and UNIL-CHUV scientists create first map of human HIV resistance

Researchers identify agricultural management practices that can reduce contamination risk in produce

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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