Polymerase Chain Reaction News and Research

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Polymerase chain reaction (PCR) is a revolutionary laboratory technique that enables the replication of a specific DNA sequence. Using PCR, millions of copies of a target DNA can be easily synthesized within a short period of time.

The WHO announces four MERS cases from Saudi Arabia in recent weeks

A recent disease outbreak alert released by the World Health Organization (WHO) reported four laboratory-confirmed cases of Middle East respiratory syndrome coronavirus (MERS-CoV) from three regions in the Kingdom of Saudi Arabia.

21 Nov 2022

Beetroot juice appears to affect gut microbiome, positively impacting intestinal and systemic health

In a recent study published in the Food Chemistry journal, researchers investigated the impact of consuming red beetroot juice for two weeks on gut microbiota.

21 Nov 2022

Kiwira virus: a new bat-borne hantavirus detected in Africa

Researchers discover a novel hantavirus called the Kiwira virus.

21 Nov 2022

WHO‒recommended alcohol-based hand rub formulations show efficacy against Monkeypox virus

Researchers demonstrated the efficacy of two World Health Organization (WHO)‒recommended alcohol-based hand rub solutions to inactivate the monkeypox virus (MPXV).

21 Nov 2022

Frozen and viable: successful culture of replicating SARS-CoV-2 from hospital aerosol samples after freezing

Researchers demonstrated the presence of infectious SARS-CoV-2 in samples from the hospital rooms of SARS-CoV-2-infected patients.

21 Nov 2022

Study suggests bats are an underrecognized arenavirus reservoir

Researchers reported the detection of arenavirus RNA from various species of bats sampled between 2007 and 2011 from Brazil.

21 Nov 2022

Researchers identify a novel RSV variant associated with prolonged infection

Researchers examine pathogen or host genetic risk factors for RSV infection, as well as whether certain viral variants are associated with prolonged infection.

20 Nov 2022

Scientists explore bat sarbecovirus isolation in Japan

Researchers performed bat sarbecovirus isolation experiments using Rhinolophus cornutus bats from several regions in Japan that were phylogenetically situated in the same cluster of viruses related to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

18 Nov 2022

Bombali ebolavirus has been detected among bats in Mozambique

Researchers reported on the detection of Bombali virus (BOMV, of the ebolavirus genus) ribonucleic acid (RNA) among three free-tailed Mops condylurus (Molossidae) bat species in Mozambique.

18 Nov 2022

What is the immune protection generated by SARS-CoV-2 Delta and Omicron BA.1 and BA.2 against Omicron BA.4 and BA.5?

Researchers evaluated immune protection conferred by previous SARS-CoV-2 Delta variant and Omicron BA.1/BA.2 subvariant infections and updated vaccines against Omicron BA.4/5 infections and associated hospitalizations.

17 Nov 2022

What is the prevalence of contraindications to Paxlovid among hospitalized COVID-19 patients?

Researchers examined the prevalence of contraindications to nirmatrelvir-ritonavir (Paxlovid) in hospitalized coronavirus disease 2019 (COVID-19) patients.

17 Nov 2022

Comparing post–COVID-19 symptoms two years after SARS-CoV-2 infection

Researchers compared the presence of post–coronavirus disease 2019 (COVID-19) symptoms among hospitalized and non-hospitalized patients in Spain.

17 Nov 2022

Study concludes monkeypox virus is readily detected by qPCR using three clinically validated assays

Researchers validated monkeypox virus (MPXV) quantitative polymerase chain reaction (qPCR) assays.

17 Nov 2022

SARS-CoV-2 RNA levels, IFN-1, ISGs, and NF-κB gene responses within the respiratory tract of mild and severe COVID-19 patients

Researchers characterized the expression of IFN-1 and IFN-2, ISGs, and NF-κB in the upper respiratory tracts of patients with mild and severe COVID-19, to understand innate immune responses to SARS-CoV-2 infections.

17 Nov 2022

Omicron BA.2 causes more symptoms and a greater disruption to daily life

In a recent study published in the Nature Communications journal, researchers monitored the changing symptom profiles associated with different severe acute respiratory syndrome CoV-2 (SARS-CoV-2) variants, especially Omicron subvariants BA.1 and BA.2.

16 Nov 2022

Could self-collected swabs play a role in the diagnosis and control of monkeypox?

In a recent study published in the journal Clinical Infectious Diseases, researchers evaluated the accuracy of patient-collected samples in diagnosing monkeypox virus infections.

16 Nov 2022

Development of a potent, broadly protective vaccine against all SARS-CoV-2 variants

In a recent study published in the journal npj Vaccines, researchers in China designed, produced, and evaluated the neutralization efficacy of a recombinant coronavirus disease 2019 (COVID-19) vaccine containing four hot-spot substitution mutations based on a prefusion-stabilized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (S) trimer.

15 Nov 2022

Polymerase Chain Reaction News and Research

Further Reading

The WHO announces four MERS cases from Saudi Arabia in recent weeks

Beetroot juice appears to affect gut microbiome, positively impacting intestinal and systemic health

Kiwira virus: a new bat-borne hantavirus detected in Africa

WHO‒recommended alcohol-based hand rub formulations show efficacy against Monkeypox virus

Frozen and viable: successful culture of replicating SARS-CoV-2 from hospital aerosol samples after freezing

Study suggests bats are an underrecognized arenavirus reservoir

Researchers identify a novel RSV variant associated with prolonged infection

Scientists explore bat sarbecovirus isolation in Japan

Bombali ebolavirus has been detected among bats in Mozambique

What is the immune protection generated by SARS-CoV-2 Delta and Omicron BA.1 and BA.2 against Omicron BA.4 and BA.5?

What is the prevalence of contraindications to Paxlovid among hospitalized COVID-19 patients?

Comparing post–COVID-19 symptoms two years after SARS-CoV-2 infection

Study concludes monkeypox virus is readily detected by qPCR using three clinically validated assays

SARS-CoV-2 RNA levels, IFN-1, ISGs, and NF-κB gene responses within the respiratory tract of mild and severe COVID-19 patients

Omicron BA.2 causes more symptoms and a greater disruption to daily life

Could self-collected swabs play a role in the diagnosis and control of monkeypox?

Development of a potent, broadly protective vaccine against all SARS-CoV-2 variants

Long-COVID symptoms worsened by stressful events

Black, Hispanic MSM disproportionately affected by monkeypox

SARS-CoV-2 transmission among asymptomatic cases is lower

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