Polymerase Chain Reaction News and Research

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Polymerase chain reaction (PCR) is a revolutionary laboratory technique that enables the replication of a specific DNA sequence. Using PCR, millions of copies of a target DNA can be easily synthesized within a short period of time.

Study suggests SARS-CoV-2 Omicron is as deadly as past variants

A recent article under review at the Nature Portfolio journal and currently posted to the Research Square* preprint server compared the severity of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant with prior mutants.

4 May 2022

Pets living in households with COVID-19 are high likely to seroconvert and become ill

In a recent study published in the journal Emerging Infectious Diseases, researchers investigated whether pet dogs and cats in the households of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected humans were at risk of infection.

3 May 2022

How a COVID support team mitigated SARS-CoV-2 transmission within a university community

Researchers demonstrated how a campus coronavirus disease support team [CCST] efficiently mitigated potential COVID 2019 (COVID-19) outbreaks within the school of public health (SPH) of the mid-Atlantic university in the United States (US).

3 May 2022

SARS-CoV-2 inhibition mediated by cellular nucleic acid-binding protein

A recent study under review at Nature Portfolio and posted to the Research Square* preprint server depicted how cellular nucleic acid-binding protein (CNBP) inhibits severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

3 May 2022

Study explores which occupations had the greatest risk of SARS-CoV-2 infection and how relative differences varied over the pandemic

Researchers investigated occupations at the highest risk for SARS-CoV-2 infection.

3 May 2022

Effectiveness of ChAdOx1-S COVID-19 booster vaccine

Researchers assessed the effectiveness of ChAdOx1-S COVID-19 booster vaccination.

3 May 2022

Prior SARS-CoV-2 infection provides substantial and sustained protection from Omicron hospitalization

A population-level study conducted on residents of the Quebec province, Canada, has demonstrated that prior infection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces robust and long-lasting protection against omicron re-infection and hospitalization. The level of protection further increases with coronavirus disease 2019 (COVID-19) vaccination.

3 May 2022

Novel wearable sensor can detect two key biomarkers of infection in sweat

University of Texas at Dallas bioengineers in collaboration with EnLiSense LLC have designed a wearable sensor that can detect two key biomarkers of infection in human sweat, a significant step toward making it possible for users to receive early warnings of infections such as COVID-19 and influenza.

2 May 2022

Tracking BA.2.12.1 🦠 by partial ORF1ab gene 🧬 target failure (pOGTF)

Scientists from the United States have recently identified a novel approach to rapidly and accurately detect the omicron BA.2.12.1 sub-lineage of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in clinical samples.

2 May 2022

Estimating COVID-19 case prevalence in New York City

Researchers estimated the prevalence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in New York City (NYC).

2 May 2022

Neutralizing antibodies produced following COVID-19 BNT162b2 vaccine found to activate complement cascade

Researchers investigated the complement component 1q (C1q) binding and subsequent complement activation by neutralizing antibodies (nAbs) produced following COVID-19 vaccination.

2 May 2022

SARS-CoV-2 viral shedding varies widely in asymptomatic and mildly ill patients

In a recent study published in the Nature Microbiology journal, researchers assessed the longitudinal viral dynamics in asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

1 May 2022

Poor asthma control triggered by SARS-CoV-2

In a new study, researchers noted that COVID-19 could trigger poor pediatric asthma control.

29 Apr 2022

Study evaluates hybridization probe capture for enriching coronavirus genomic material in bat oral and rectal swabs

Researchers surveilled coronaviruses found in bats via targeted genomic sequencing.

29 Apr 2022

Clinical characteristics of immunocompromised patients infected with the SARS-CoV-2 Omicron variant

Researchers examined the characteristics and outcomes of COVID-19 in immunocompromised patients.

29 Apr 2022

Artificial circular RNAs found to bypass cellular antiviral responses

Researchers produced artificial circular ribonucleic acid sponges in a permuted intron-exon system and showed that these did not activate innate immunity.

29 Apr 2022

Findings of the HITCH randomized clinical trial show lack of improvement in COVID-19 on temporary androgen suppression

Researchers investigated whether temporary androgen suppression by degarelix improved the clinical outcomes among male patients hospitalized with COVID-19.

27 Apr 2022

How severity and progression of COVID-19 affect cytokine profiles in pregnant women

The current study deals with the results of serum cytokine analysis in a small group of pregnant women with and without COVID-19 in the third trimester in a single New York City hospital.

27 Apr 2022

Potential diagnostic method for identifying human health-relevant nucleic acids utilizing FokI-assisted digestion of DNA duplexes and DNA/RNA hybrids

Researchers revealed that native FokI relaxation might be induced, resulting in FokI-assisted digestion of DNA duplexes and DNA/RNA hybrids.

27 Apr 2022

Asymptomatic SARS-CoV-2 infection among research personnel: Study

A recent research paper published in the journal Public Library of Science (PLOS) ONE analyzed asymptomatic coronavirus disease 2019 (COVID-19) in personnel engaged in academic study.

26 Apr 2022

Polymerase Chain Reaction News and Research

Further Reading

Study suggests SARS-CoV-2 Omicron is as deadly as past variants

Pets living in households with COVID-19 are high likely to seroconvert and become ill

How a COVID support team mitigated SARS-CoV-2 transmission within a university community

SARS-CoV-2 inhibition mediated by cellular nucleic acid-binding protein

Study explores which occupations had the greatest risk of SARS-CoV-2 infection and how relative differences varied over the pandemic

Effectiveness of ChAdOx1-S COVID-19 booster vaccine

Prior SARS-CoV-2 infection provides substantial and sustained protection from Omicron hospitalization

Novel wearable sensor can detect two key biomarkers of infection in sweat

Tracking BA.2.12.1 🦠 by partial ORF1ab gene 🧬 target failure (pOGTF)

Estimating COVID-19 case prevalence in New York City

Neutralizing antibodies produced following COVID-19 BNT162b2 vaccine found to activate complement cascade

SARS-CoV-2 viral shedding varies widely in asymptomatic and mildly ill patients

Poor asthma control triggered by SARS-CoV-2

Study evaluates hybridization probe capture for enriching coronavirus genomic material in bat oral and rectal swabs

Clinical characteristics of immunocompromised patients infected with the SARS-CoV-2 Omicron variant

Artificial circular RNAs found to bypass cellular antiviral responses

Findings of the HITCH randomized clinical trial show lack of improvement in COVID-19 on temporary androgen suppression

How severity and progression of COVID-19 affect cytokine profiles in pregnant women

Potential diagnostic method for identifying human health-relevant nucleic acids utilizing FokI-assisted digestion of DNA duplexes and DNA/RNA hybrids

Asymptomatic SARS-CoV-2 infection among research personnel: Study

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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