Polymerase Chain Reaction News and Research

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Polymerase chain reaction (PCR) is a revolutionary laboratory technique that enables the replication of a specific DNA sequence. Using PCR, millions of copies of a target DNA can be easily synthesized within a short period of time.

25% of COVID-19 patients have lasting reduction in lung function

In a recent study posted to the Preprints with The Lancet SSRN* server, researchers evaluated the impairment of pulmonary function in individuals suffering from post-acute sequelae of coronavirus disease 2019 (COVID-19) (PASC) or long coronavirus disease (long COVID) symptoms after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

28 Feb 2023

Mass spectrometry-based identification of COVID-19 biomarkers

In a recent study published in the journal Metabolites, researchers reported that mass spectrometry (MS)-based metabolomic approaches have a high potential for biomarker discovery.

28 Feb 2023

The effects of Omicron emergence on seroprevalence and hybrid immunity in the Finnish adult population

Researchers evaluated SARS-CoV-2 seroprevalence and population-level humoral immunity among Finnish individuals between April 2020 and December 2022.

28 Feb 2023

COVID-19 does not increase the risk of Streptococcus pneumoniae infection

SARS-CoV-2 infection does not appear to influence pneumococcal colonization in the upper respiratory tract.

28 Feb 2023

Critical COVID-19 infection characterized by a shift from naïve T cell phenotypes to an expansion of cytotoxic CD4+ T lymphocyte subsets

Researchers immunophenotyped T lymphocyte responses among unvaccinated individuals, representative of the entire spectrum of the clinical presentation of COVID-19.

28 Feb 2023

COVID-19 increases risk of developing chronic diseases

Researchers determine the correlation between severity of SARS-CoV-2 infection, age, and new onset of chronic or worsening of pre-existing conditions.

28 Feb 2023

The evolution of transmissible variants harboring mutations consistent with immune escape in mild community COVID-19 cases

Researchers investigate whether transmissible SARS-CoV-2 variants developed during infection by culturing and sequencing strains obtained from serial oral and nasal samples of community-residing COVID-19 patients.

28 Feb 2023

Innovative methodology to detect viral RNA

Experts from the University of Barcelona, the Institute for Advanced Chemistry of Catalonia, the Institute of Microelectronics of Barcelona and the Aragon Nanoscience and Materials Institute of Aragon —a joint institute of the CSIC and the University of Zaragoza— have developed a new method to detect RNA viruses based on the triplex-forming probe technology.

27 Feb 2023

Does a negative COVID-19 test before air travel reduce the spread of COVID-19 transmission during and after travel?

Researchers assessed the impact of pre-departure testing on SARS-CoV-2-positivity rates post-arrival among international travelers.

27 Feb 2023

High-dose ivermectin does not reduce COVID-19 symptom duration among mild-to-moderate outpatients

Researchers evaluate the efficacy of ivermectin in a maximum dosage of 600 μg/kg/day over six days in treating early mild-to-moderate COVID-19.

27 Feb 2023

Study shows COVID-19 rates were likely forty-times higher than CDC estimates during BA.4/BA.5 dominant period in the U.S.

Researchers evaluate the prevalence of SARS-CoV-2 infections and the incidence of long COVID during BA.4/BA.5 dominant period.

27 Feb 2023

Exploring Mpox severity among advanced HIV patients

Researchers assessed the incidence of mpox in individuals with advanced human immunodeficiency virus (HIV) infection.

24 Feb 2023

How the delivery of family-centered care practices were impacted for neonates born to mothers with perinatal SARS-CoV-2 infection during the COVID-19 pandemic

Researchers evaluated the effects of the COVID-19 pandemic on family-centered care practices for infants born to SARS-CoV-2-infected mothers.

24 Feb 2023

Does COVID-19 accelerate the worsening of clinical disabilities in multiple sclerosis patients?

The researchers investigated the impact of coronavirus disease 2019 (COVID-19) on the progression of clinical disability in multiple sclerosis patients.

24 Feb 2023

Following third dose of BNT162b2, adverse events increased in those with prior COVID-19

Previous SARS-CoV-2 infection exacerbates the adverse reactions experienced after receipt of the third booster dose.

23 Feb 2023

Is the advantage conferred by the heterologous regimen conserved after a booster dose of mRNA-based COVID-19 vaccine?

Researchers compared the efficacy of a third COVID-19 vaccine dose and that of homologous and heterologous regimens.

23 Feb 2023

Researchers report the circulation of a novel MERS-like coronavirus in Malayan pangolins

Researchers reported the circulation of a novel MERS-like coronavirus among Malayan pangolins, Manis javanica HKU4-associated CoV (MjHKU4r-CoV).

21 Feb 2023

In-depth assessment of muscle biopsies in patients with long COVID

Researchers analyzed skeletal muscle biopsies of patients with persistent fatigue and malaise post-exertion to determine the underlying mechanisms of long COVID.

20 Feb 2023

Prior COVID highly protective against severe disease ten months post-infection

In a recent study published in the Lancet, researchers performed a systematic review of scientific literature published from inception up to September 31, 2022, that documented the reduction in risk of coronavirus disease 2019 (COVID-19) among individuals with a prior severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection vis-à-vis those with no COVID-19 history.

19 Feb 2023

After a previous BA.1 infection, Omicron BA.4/5 infection is more likely than BA.2

In a recent study published in the journal Eurosurveillance, researchers investigated whether prior severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and/or coronavirus disease 2019 (COVID-19) vaccination protected against SARS-CoV-2 Omicron variant of concern (VOC) BA.4/5 sub-VOC or BA.2 sub-VOC infections.

19 Feb 2023

Polymerase Chain Reaction News and Research

Further Reading

25% of COVID-19 patients have lasting reduction in lung function

Mass spectrometry-based identification of COVID-19 biomarkers

The effects of Omicron emergence on seroprevalence and hybrid immunity in the Finnish adult population

COVID-19 does not increase the risk of Streptococcus pneumoniae infection

Critical COVID-19 infection characterized by a shift from naïve T cell phenotypes to an expansion of cytotoxic CD4+ T lymphocyte subsets

COVID-19 increases risk of developing chronic diseases

The evolution of transmissible variants harboring mutations consistent with immune escape in mild community COVID-19 cases

Innovative methodology to detect viral RNA

Does a negative COVID-19 test before air travel reduce the spread of COVID-19 transmission during and after travel?

High-dose ivermectin does not reduce COVID-19 symptom duration among mild-to-moderate outpatients

Study shows COVID-19 rates were likely forty-times higher than CDC estimates during BA.4/BA.5 dominant period in the U.S.

Exploring Mpox severity among advanced HIV patients

How the delivery of family-centered care practices were impacted for neonates born to mothers with perinatal SARS-CoV-2 infection during the COVID-19 pandemic

Does COVID-19 accelerate the worsening of clinical disabilities in multiple sclerosis patients?

Following third dose of BNT162b2, adverse events increased in those with prior COVID-19

Is the advantage conferred by the heterologous regimen conserved after a booster dose of mRNA-based COVID-19 vaccine?

Researchers report the circulation of a novel MERS-like coronavirus in Malayan pangolins

In-depth assessment of muscle biopsies in patients with long COVID

Prior COVID highly protective against severe disease ten months post-infection

After a previous BA.1 infection, Omicron BA.4/5 infection is more likely than BA.2

Exploring the intersection of biology and proteomics

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

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