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OGF-OGFr axis discovery provides new insights into ovarian cancer

Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered that the presence and integrity of the opioid growth factor receptor (OGFr), which mediates the inhibitory action of opioid growth factor (OGF) on cell proliferation, is a key to understanding the progression and treatment of human ovarian cancer.

22 Feb 2012

Study: MRSA jumps from food animals to humans

A strain of the potentially deadly antibiotic-resistant bacterium known as MRSA has jumped from food animals to humans, according to a new study involving two Northern Arizona University researchers.

22 Feb 2012

BioLineRx BL-7010 may reduce gluten toxicity in patients with celiac disease

BioLineRx, a biopharmaceutical development company, announced the publication of pre-clinical results demonstrating that BL-7010, an orally available treatment for celiac disease, reduces gluten toxicity (the negative effect of gluten on the patient's body).

22 Feb 2012

New chemical compound to treat brain damage from stroke

Researchers at the University of Copenhagen have designed, produced and patented a new chemical compound for the possible treatment of brain damage caused by stroke. The compound binds 1,000 times more effectively to the target protein in the brain than the potential drug currently being tested on stroke victims.

22 Feb 2012

Mitochondria may be promising new target for cancer treatment

Mitochondria, tiny structures within each cell that regulate metabolism and energy use, may be a promising new target for cancer therapy, according to a new study. Manipulation of two biochemical signals that regulate the numbers of mitochondria in cells could shrink human lung cancers transplanted into mice, a team of Chicago researchers report in the journal FASEB.

22 Feb 2012

Insulin production may persist for decades after onset of type 1 diabetes

Massachusetts General Hospital (MGH) research has found that insulin production may persist for decades after the onset of type 1 diabetes. Beta cell functioning also appears to be preserved in some patients years after apparent loss of pancreatic function. The study results appear in the March issue of Diabetes Care.

22 Feb 2012

Researchers study specially bred mice to understand annual flu epidemics

As part of a national collaboration, Oregon Health & Science University researchers are studying specially bred mice that are more like humans than ever before when it comes to genetic variation. Through these mice, the researchers hope to better understand and treat an infectious disease that plagues us year in and year out: the flu.

22 Feb 2012

IDOM researchers overturn textbook view of liver metabolism

A team led by researchers from the Institute for Diabetes, Obesity and Metabolism (IDOM) at the Perelman School of Medicine, University of Pennsylvania, has overturned a "textbook" view of what the body does after a meal.

22 Feb 2012

AChemS recognizes Monell Center molecular biologist as outstanding junior scientist

Molecular biologist Ichiro Matsumoto, Ph.D., of the Monell Center, is the recipient of the 2012 Ajinomoto Award for Young Investigators in Gustation, awarded annually by the Association for Chemoreception Sciences (AChemS) to an outstanding junior scientist who is an emerging leader in the field of gustation.

22 Feb 2012

DANSR/FORTE assay more effective in diagnosing Edwards and Down syndrome

Using a noninvasive test on maternal blood that deploys a novel biochemical assay and a new algorithm for analysis, scientists can detect, with a high degree of accuracy, the risk that a fetus has the chromosomal abnormalities that cause Down syndrome and a genetic disorder known as Edwards syndrome.

22 Feb 2012

USAID assisting communities affected by cyclones in Eastern Africa

In this post on USAID's "IMPACTblog," the agency describes its activities in "assisting communities and individuals impacted by the cyclones in Madagascar, Mozambique, and Malawi."

22 Feb 2012

Key regulator of lens development also controls mechanosensory neuron development

A gene known to control lens development in mice and humans is also crucial for the development of neurons responsible for mechanosensory function, as neurobiologists of the Max Delbr-ck Center for Molecular Medicine (MDC) Berlin-Buch have now discovered.

22 Feb 2012

Fructose may not be to blame for obesity

Is fructose being unfairly blamed for the obesity epidemic? Or do we just eat and drink too many calories? Researchers from St. Michael's Hospital reviewed more than 40 published studies on whether the fructose molecule itself causes weight gain.

22 Feb 2012

UMC Utrecht, DSM collaborate for Dyneema Purity fiber technology

DSM, a global leader in biomedical materials sciences, and University Medical Center Utrecht, a leading academic hospital with a renowned experimental facility unit for cardiothoracic interventions today announced that they have entered into a collaboration agreement.

22 Feb 2012

Sociologists develop a theory of moral self

Why do some people behave morally while others do not? Sociologists at the University of California, Riverside and California State University, Northridge have developed a theory of the moral self that may help explain the ethical lapses in the banking, investment, and mortgage-lending industries that nearly ruined the U.S. economy.

22 Feb 2012

PNAS selects six papers to receive 2011 Cozzarelli Prize

The Proceedings of the National Academy of Sciences (PNAS) Editorial Board has selected six papers published by PNAS in 2011 to receive the Cozzarelli Prize, an award that recognizes outstanding contributions to the scientific disciplines represented by the National Academy of Sciences.

22 Feb 2012

DRG cells may hold potential for nerve transplants

The carnage evident in disasters like car wrecks or wartime battles is oftentimes mirrored within the bodies of the people involved. A severe wound can leave blood vessels and nerves severed, bones broken, and cellular wreckage strewn throughout the body - a debris field within the body itself.

22 Feb 2012

Breastfeeding mother's consumption of caffeine may cause wakefulness and irritability in the baby

Babies are not able to metabolize or excrete caffeine very well, so a breastfeeding mother's consumption of caffeine may lead to caffeine accumulation and symptoms such as wakefulness and irritability, according to an interview with expert Ruth Lawrence, MD, published in Journal of Caffeine Research, a peer-reviewed journal from Mary Ann Liebert, Inc.

22 Feb 2012

Combination of gemcitabine and MRK003 kills pancreatic cancer cells

Cancer Research UK scientists have revealed how a combination of two very different drugs - currently being tested in clinical trials - amplifies the destruction of pancreatic cancer cells, according to research published in the Journal of Experimental Medicine, today.

22 Feb 2012

Immunization against flu during pregnancy can influence fetal growth

Vaccinating pregnant women against the influenza virus appears to have a significant positive effect on birth weight in babies, according to a study published in CMAJ.

22 Feb 2012