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The Nation examines rise in unregulated drug trials in South America

The Nation examines how a surge in the outsourcing of clinical trials to contract research organizations (CROs) and a resulting increase in the number of trials being conducted in the developing world, where "regulations aren't as onerous, patient recruitment is easier and informed consent is less clearly defined," has led to a rise in unregulated drug trials in South America.

27 Sep 2011

Close link between SF3B1 mutation and specific feature of myelodysplastic syndromes

Geneticists have discovered that a gene involved in the modification of ribonucleic acid (RNA) is mutated in a significant proportion of people with a collection of blood cancers called myelodysplastic syndromes.

27 Sep 2011

Sierra Leone First Lady discusses work to improve maternal mortality

NPR's Tell Me More on Friday interviewed Sierra Leone First Lady Sia Nyama Koroma about her work aimed at improving maternal health in her country. Koroma was in New York attending the African First Ladies Fellowship Program "that brings together Western European and American first ladies with their African counterparts for an exchange of ideas and best practices," according to the program.

27 Sep 2011

HCRI completes enrollment in dual antiplatelet therapy clinical trial

The Harvard Clinical Research Institute (HCRI) announced today that the enrollment phase of the DAPT Study has been successfully completed. The DAPT Study is a four-year clinical trial investigating the duration of dual antiplatelet therapy (DAPT, the combination of aspirin and a thienopyridine/antiplatelet medication to reduce the risk of blood clots) following drug-eluting stent implantations.

27 Sep 2011

Afraxis to participate in NIH's Therapeutics for Rare and Neglected Disease Program

Afraxis, a San Diego-based biotechnology company developing drugs to treat rare genetic diseases through the modulation of p21-activated kinase (PAK), announced today that it has been selected to participate in the National Institutes of Health's (NIH) Therapeutics for Rare and Neglected Disease (TRND) Program.

27 Sep 2011

CHRI second quarter revenues increase to $8 million

China Health Resource, Inc., a producer and supplier of Traditional Chinese Medicine (TCM) products, announced robust quarterly earnings for June 2011.

27 Sep 2011

Investing now in early child development will have long-term benefits

Gordon Alexander, director of the office of research at UNICEF's Innocenti Research Centre, writes in this post on the Guardian's "Poverty Matters Blog" that a series published in Friday's Lancet on early child development (ECD) shows "that the payoff from concerted, integrated action around ECD would be enormous."

27 Sep 2011

Insurers, patients wrestle with payment, care issues and strategies

News outlets report on a variety of issues reflecting the insurance hassles patients sometimes face and the efforts by insurance companies to find profits in better-coordinated care.

27 Sep 2011

Subtle and unspoken clues exchanged by patients, doctors exert an influence on medical care

Subtle and unspoken clues exchanged by patients and doctors exert an influence on medical care, according to a new study by the University of Michigan Health System. Researchers analyzed video recordings of routine checkups and conducted follow-up interviews with participants to help elucidate signals sent and received on both sides of the examination table.

27 Sep 2011

Congressional mood, 'super committee' news highlight difficulties

The New York Times reports that expectations for the deficit-reduction panel continue to drop, as the Democrats' and Republicans' respective positions on trimming entitlements and raising taxes appear to be hardening. And, in the background, The Wall Street Journal notes that another government shutdown looms as lawmakers fail to make progress in striking a deal to fund the federal branch through Nov. 18.

27 Sep 2011

Patients with chronic conditions likely to change their preferences for CPR

Patients with chronic conditions are likely to change their preferences for receiving emergency procedures in the event of cardiac arrest, according to new findings.

27 Sep 2011

U.S. commits additional funds to Clean Cookstoves initiative

On the one-year anniversary of the launch of the Global Alliance for Clean Cookstoves, the U.S. made an additional financial commitment of up to $55 million, "bringing the total United States commitment to up to $105 million in the first five years," according to a State Department press release.

27 Sep 2011

Lead compound activates infection-fighting REDD1 protein and kills flu strain

A compound tested by UT Southwestern Medical Center investigators destroys several viruses, including the deadly Spanish flu that killed an estimated 30 million people in the worldwide pandemic of 1918.

27 Sep 2011

Immediate action needed to curb spread of TB, especially among children

In this post in the Huffington Posts "Impact" blog, Kolleen Bouchane, director of ACTION, an international partnership of advocates working to mobilize resources to treat and prevent the spread of tuberculosis (TB), examines the need for improved TB vaccines and diagnostics in order to curb the spread of multidrug-resistant TB, especially among children, and highlights ACTION's new report.

27 Sep 2011

UCLA researchers sequence complete genomes of 17 strains of mice

For decades, laboratory mice have been widely used in research aimed at understanding which genes are involved in various illnesses. But actual variations in past gene sequences of mice were unknown. While researchers were able to determine that a variant affecting disease was in a certain region, they couldn't pinpoint the exact set of variants in that region.

27 Sep 2011

Dem lawmakers, advocates push to save CLASS Act

The Hill reports that backers of this long-term care program, including congressional Democrats, say the administration can continue working on its developments using money from the health law.

27 Sep 2011

Scientists uncover how methylation changes can influence blood stem cell's fate

Scientists at Cold Spring Harbor Laboratory (CSHL) and the University of Southern California (USC) have uncovered intriguing new evidence helping to explain one of the ways in which a stem cell's fate can be determined.

27 Sep 2011

Obama administration decision could impact timing of Supreme Court ruling

The Justice Department must decide today whether to ask the full U.S. 11th Circuit Court of Appeals to reconsider a 2-1 August decision declaring unconstitutional the health law's individual mandate. If it does seek the full court's review, which could take weeks or months, it will likely push back a Supreme Court ruling until 2013.

27 Sep 2011

New Banner MD Anderson center to deliver unprecedented cancer care in Arizona

Banner MD Anderson Cancer Center, a unique collaboration between Banner Health and The University of Texas MD Anderson Cancer Center, opens today, ushering in a new era of unprecedented cancer care in Arizona.

27 Sep 2011

GlobalPost examines country ownership in GHI Rwanda program

As part of its special report "Healing the World," GlobalPost examines country ownership within the Global Health Initiative (GHI). The news service writes that Rwandan Health Minister Agnes Binagwaho told GlobalPost that a GHI focus on gender-based violence in Rwanda was a "curious" decision, which "she said ... wasn't a priority and no one had asked her if that fit in with the national plan."

27 Sep 2011