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Researchers discover cell receptor for CDT toxin of C. difficile bacterium

A research group led by Freiburg pharmacologist Prof. Dr. Klaus Aktories and their American colleagues have discovered the cell receptor for the toxin CDT of the bacterium Clostridium difficile.

27 Sep 2011

Men over 75 with prostate cancer are being undertreated: Study

It's an ongoing debate: Should men over a certain age be treated for prostate cancer? Should these patients be submitted to treatments that may result in significant side effects if they may not live very much longer?

27 Sep 2011

Roundup: Patient dies after medical error during Calif. nurses strike; grocery workers ratify contract that had partially hinged on health care

Veteran nurses locked out of Alta Bates Summit Medical Center in Oakland said Sunday that the death of a patient due to a medical error by a replacement worker wouldn't have happened if they had been allowed to do their jobs. The hospital's management countered that it was a freak accident that could have happened at any time -- with or without the replacement nurses. At the center of the dispute is a cancer patient, a woman who has not been identified but whose tragic death on Saturday has inflamed an already tense labor dispute.

27 Sep 2011

Smaller and faster clinical drug trials could improve gains in cancer survival

With the advent of personalised medicine, gains in cancer survival over the long term could be improved by running smaller, faster trials with less stringent evidence criteria, a researcher told the 2011 European Multidisciplinary Cancer Congress.

26 Sep 2011

Scientists identify a way that chemotherapy causes platelet numbers to drop

Scientists at the Walter and Eliza Hall Institute have identified a way that chemotherapy causes platelet numbers to drop, answering in the process a decade-old question about the formation of platelets, tiny cells that allow blood to clot.

26 Sep 2011

Pacira announces data from EXPAREL clinical study presented at ASPS 2011 meeting

Pacira Pharmaceuticals, Inc. today announced that the company's lead investigational product for postsurgical pain management, EXPAREL, was highlighted in the "Hot Topics in Plastic Surgery" panel at the annual scientific assembly of the American Society of Plastic Surgeons (ASPS) in Denver, Colo.

26 Sep 2011

Zoledronic acid may benefit post-menopausal women with breast cancer

A trial investigating the use of zoledronic acid to aid chemotherapy for breast cancer has found a significant benefit for post-menopausal women, according to results presented at the 2011 European Multidisciplinary Cancer Congress.

26 Sep 2011

People with COPD, reduced lung function more likely to develop cardiovascular disease

A new study has shown that people with chronic obstructive pulmonary disease (COPD) or people with reduced lung function are at a serious risk of developing cardiovascular disease.

26 Sep 2011

JDRF, iCo Therapeutics collaborate for iCo-007 Phase 2 trial in DME

iCo Therapeutics Inc. today announced that the company has entered into a research collaboration agreement with JDRF, the worldwide leader for research to cure, treat, and prevent type 1 diabetes (T1D), to support the previously announced Phase 2 investigator sponsored clinical trial investigating iCo-007 in Diabetic Macular Edema.

26 Sep 2011

First Edition: September 26, 2011

In today's headlines, KHN kicks off a three-day series, "The Big Money World Of Kid's Care."

26 Sep 2011

Duplication of RPS6KA3 gene produces limited family intellectual disability

The financial contributions made some years ago by individuals and public administration bodies in the telemarathon solidarity events on the Basque Public Broadcasting Corporation (EiTB) and subsequently channelled through the Basque Foundation for Health Innovation and Research (BIOEF), has resulted in undertaking successful innovative research at the Cruces Hospital near Bilbao in the Basque province of Bizkaia, describing a new syndrome of limited family intellectual disability.

26 Sep 2011

Asthma patients admitted to hospital with H1N1 are half as likely to die from infection

People with asthma who are admitted to hospital with pandemic influenza H1N1 (swine flu) are half as likely to die or require intensive care than those without asthma, according to new research.

26 Sep 2011

Ibandronate controls pain in prostate cancer patients with bone metastases

Many prostate cancer patients develop bone metastases, and controlling the pain these cause can be difficult. Now the first large randomised Phase III trial of a bisphosphonate drug in these patients has shown that a single dose of the drug is as good for pain relief as single dose radiotherapy, the standard treatment for bone metastases. Results of the trial were presented at the 2011 European Multidisciplinary Cancer Congress.

26 Sep 2011

Foam injections to treat varicose veins cause less pain for patients, could save NHS money

Foam injections to treat varicose veins cause less pain for patients and could save NHS money compared with a popular alternative treatment, according to researchers at Imperial College London. The study found that foam therapy was over four times more cost-effective than laser treatment and allowed patients to resume normal activity sooner. The findings were presented today at the annual meeting of the European Vascular Society in Athens.

26 Sep 2011

Effects of fruit and vegetable consumption on colorectal cancer

The effects of fruit and vegetable consumption on colorectal cancer (CRC) appear to differ by site of origin, according to a new study published in the October issue of the Journal of the American Dietetic Association.

26 Sep 2011

Study shows substantial differences in use of rectal cancer therapies across Europe

First results from an international comparison of the care of patients with rectal cancer have shown there are substantial differences in the use of chemotherapy and radiotherapy between European countries.

26 Sep 2011

Scientists reveal link between lipid cell dysfunction and metabolic diseases

By measuring the radioactive isotope carbon-14, scientists at Karolinska Institutet have revealed an association between lipid cell dysfunction and diseases such as obesity, diabetes and blood lipid disorders.

26 Sep 2011

Vaxent, PREVENT sign license agreement to develop and commercialize Strep-A vaccine

An international collaboration between Vaxent, a Memphis-based early stage vaccine development company in the Memphis Bioworks Foundation Incubator, and The Pan-Provincial Vaccine Enterprise Inc. (PREVENT), a Centre of Excellence for Commercialization and Research (CECR) in Saskatchewan, has put a vaccine for group A streptococcus (Strep-A) back on the path for potential commercialization.

26 Sep 2011

City cyclists inhale more black carbon than pedestrians

People who cycle through London and other major cities have higher levels of black carbon in their airway cells, experts from the UK have shown.

26 Sep 2011

Afinitor Phase III study on angiomyolipomas associated with TSC meets primary endpoint

A Phase III study of Afinitor (everolimus) tablets in patients with non-cancerous kidney tumors, or angiomyolipomas, associated with tuberous sclerosis complex (TSC) met its primary endpoint of best overall angiomyolipoma response rate, which includes reduction in kidney tumor size and absence of new tumors.

26 Sep 2011

Research News and Research

Researchers discover cell receptor for CDT toxin of C. difficile bacterium

Men over 75 with prostate cancer are being undertreated: Study

Roundup: Patient dies after medical error during Calif. nurses strike; grocery workers ratify contract that had partially hinged on health care

Smaller and faster clinical drug trials could improve gains in cancer survival

Scientists identify a way that chemotherapy causes platelet numbers to drop

Pacira announces data from EXPAREL clinical study presented at ASPS 2011 meeting

Zoledronic acid may benefit post-menopausal women with breast cancer

People with COPD, reduced lung function more likely to develop cardiovascular disease

JDRF, iCo Therapeutics collaborate for iCo-007 Phase 2 trial in DME

First Edition: September 26, 2011

Duplication of RPS6KA3 gene produces limited family intellectual disability

Asthma patients admitted to hospital with H1N1 are half as likely to die from infection

Ibandronate controls pain in prostate cancer patients with bone metastases

Foam injections to treat varicose veins cause less pain for patients, could save NHS money

Effects of fruit and vegetable consumption on colorectal cancer

Study shows substantial differences in use of rectal cancer therapies across Europe

Scientists reveal link between lipid cell dysfunction and metabolic diseases

Vaxent, PREVENT sign license agreement to develop and commercialize Strep-A vaccine

City cyclists inhale more black carbon than pedestrians

Afinitor Phase III study on angiomyolipomas associated with TSC meets primary endpoint

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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