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Cholesterol-lowering statins reduce rate of mortality and cardiovascular events

Over the long term, treatment with cholesterol-lowering statins reduces the rate of mortality and cardiovascular events such as heart attack, for people with and without heart disease. Still, it is unclear whether these drugs take effect rapidly when the risk of these dire events is highest.

15 Jun 2011

Placental growth factor also plays a role in chronic myeloid leukemia

Chronic myeloid leukemia (CML) is a particular form of leukemia or cancer of the bone marrow, which can be treated with targeted imatinib. However, in some cases this medicine has no effect. Researchers at the VIB Vesalius Research Centre, K.U. Leuven, under the direction of Peter Carmeliet, have investigated the role of placental growth factor (PlGF) in mice with CML.

15 Jun 2011

Spectrum board authorizes $25 million stock repurchase program

Spectrum Pharmaceuticals, Inc., a biotechnology company with fully integrated commercial and drug development operations with a primary focus in oncology, today announced that its Board of Directors has authorized the purchase of up to $25 million of its common stock through the end of 2012.

15 Jun 2011

Magnesium essential for absorption and metabolism of vitamin D and calcium

Magnesium deficiency is an important factor in the results obtained from vitamin D. According to Dr. Carolyn Dean, MD, ND, magnesium expert and Medical Director of the nonprofit Nutritional Magnesium Association, the effectiveness and benefits of vitamin D are greatly undermined in the absence of adequate levels of magnesium in the body.

15 Jun 2011

Bariatric surgery reduces incidence and severity of migraines

Bariatric surgery can lead to total or partial alleviation of migraines in nearly 90 percent of morbidly obese patients diagnosed with migraine headaches, according to a new study presented here at the 28th Annual Meeting of the American Society for Metabolic & Bariatric Surgery (ASMBS).

15 Jun 2011

Alkermes commences ALKS 5461 phase 1/2 study for treatment-resistant depression

Alkermes, Inc. today announced the initiation of a phase 1/2 study of ALKS 5461 for treatment-resistant depression (TRD). ALKS 5461 is the combination of ALKS 33, a proprietary opioid modulator, and buprenorphine. TRD, which is also known as refractory depression, refers to depressive episodes that are not adequately controlled by standard antidepressant therapy.

15 Jun 2011

Overactive mTOR can result in serious disruption of kidney filter in diabetes patients

Diabetes mellitus is one of the most common secondary diseases in modern society. And because it is on the rise, it is also one of the greatest challenges facing medicine today. Diabetes patients do not die as a direct result of the increase in blood sugar, but from the long-term complications of their disease, in which the increase in blood sugar causes damage to blood vessels and organs.

15 Jun 2011

NIH awards $20 million research grant to University of Kentucky

The National Institutes of Health (NIH), the largest government funding source for biomedical research in the United States, has awarded $20 million to the University of Kentucky to move research discoveries to health care solutions more quickly.

15 Jun 2011

There is no such thing as expressive muscles

According to doctors during the interwar period, wide hips made women unsuitable for running long distances. In her recent doctoral thesis, Kerstin Bornholdt looks at how researchers reached conclusions like this.

15 Jun 2011

Childhood cancer survivors at increased risk of new cancers in middle age

CANCER RESEARCH UK scientists have found that survivors of childhood cancers are four times more likely than the general population to develop a new cancer. The results are published online today in JAMA.

15 Jun 2011

First Edition: June 15, 2011

Today's early morning highlights from the major news organizations, including a report that GOP governors are pushing back against federal Medicaid rules.

15 Jun 2011

High number of adverse patient safety events occur in doctors' offices

However, a high number of adverse events, including major injury and even death, occur in private physician offices and outpatient clinics as well. In a new study -- the first of its kind -- researchers at Weill Cornell Medical College found that the number and magnitude of events resulting from medical errors is surprisingly similar inside and outside hospital walls.

15 Jun 2011

Scientists zero in on dose levels of "sacred mushroom"

Scientists at the Johns Hopkins University School of Medicine have zeroed in on the dose levels of the "sacred mushroom" chemical capable of yielding positive, life-changing experiences, while minimizing the chance of transient negative reactions in screened volunteers under supportive, carefully monitored conditions.

15 Jun 2011

Essential benefits rule, McKinsey study continue to draw headlines

Also, Neal Katyal, the acting solicitor general who has argued four of the cases challenging the health law before appeals courts, has announced that he will leave the Department of Justice at the conclusion of the current Supreme Court term.

15 Jun 2011

Long carbon nanotubes could cause cancer in the lung lining

Tiny fibres used to strengthen everyday products such as bicycle frames and hockey sticks could pose health hazards to those involved in their manufacture.

15 Jun 2011

FDA issues final rulemaking on testing and labeling of sunscreen products

"FDA's recognition today of the important role sunscreens play in protecting the public not only from sunburn but also from skin cancer and premature aging due to the sun is a very significant victory for public health. The role of UV rays in causing skin damage and the role of sunscreens in protecting against this sun damage are widely acknowledged within the medical and scientific communities, and we're very pleased the agency has taken this critical step.

15 Jun 2011

California's rural elders more likely to be obese, physically inactive and food insecure

Despite living in the countryside, where open space is plentiful and there is often significant agricultural production, California's more than half a million rural elders are far more likely to be overweight or obese, physically inactive and food insecure than their suburban counterparts, according to a new policy brief from the UCLA Center for Health Policy Research.

15 Jun 2011