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Apeiron in antitumor substances deal with Cleveland Clinic

APEIRON Biologics AG announced that it has entered into an exclusive option to license from the Cleveland Clinic a number of novel compounds. These compounds are currently in development at Cleveland Clinic as drug candidates for treatment of various cancers, designed to fight cancer based on stimulation of the immune system. In preclinical models, they have shown anti-cancer activity and a favourable toxicity profile as orally available agents.

15 Mar 2011

Emergency responders, insurers, communicators must factor overconfidence into disaster preparations

Past random good fortune can lull a person into a sense of security when it comes to buying flood insurance or deciding whether to evacuate from a hurricane, according to new research. Studies of both professional risk experts and the general public showed people who had experienced a “near-miss” event related to flooding or a potential hurricane, instead of taking extra precautions when faced with possible future disasters, actually behave less protectively.

15 Mar 2011

Discovery of molecular switch for the secretion of insulin

Johns Hopkins researchers believe they have uncovered the molecular switch for the secretion of insulin — the hormone that regulates blood sugar — providing for the first time an explanation of this process. In a report published online March 1 in Cell Metabolism, the researchers say the work solves a longtime mystery and may lead to better treatments for type 2 diabetes, the most common form of the disease.

15 Mar 2011

Researchers set to study impacts of space radiation on the atmosphere and aging issues worldwide

Researchers from the University of Alberta have won awards from an international research organization that will enable them to work with colleagues around the globe to address two issues with global ramifications.

15 Mar 2011

Medicago receives $3.8M as second milestone payment from U.S. DARPA for cGMP vaccine facility

Medicago USA Inc., a wholly owned subsidiary of Medicago Inc., a biotechnology company focused on developing highly effective and competitive vaccines based on proprietary manufacturing technologies and Virus-Like Particles (VLPs), today announced it has received the second milestone payment of US$3.8 million from the Defense Advanced Research Projects Agency ("DARPA").

15 Mar 2011

Newer, more expensive treatments for prostate cancer adopted rapidly

With 180,000 men diagnosed with prostate cancer each year, it is one of the most common types of cancer in the country. For this reason, it has been cited as a good marker for health care spending in general, reflective of the greater trends across the United States.

15 Mar 2011

Omeros fourth quarter net loss increases to $7.2 million

Omeros Corporation, a biopharmaceutical company committed to discovering, developing and commercializing products focused on inflammation, bleeding and disorders of the central nervous system, today announced financial results for the fourth quarter and year ended December 31, 2010.

15 Mar 2011

Research links frequent prescribing to opioid-related deaths

Some physicians are prescribing opioids such as OxyContin 55 times as often as others, according to a new study led by St. Michael's Hospital and the Institute for Clinical Evaluative Sciences (ICES). The study found most opioid-related deaths occur among patients treated by physicians who frequently prescribe opioids, suggesting doctors who prescribe a lot of opioids may not be doing so safely.

15 Mar 2011

First Edition: March 15, 2011

Today's headlines include reports about the pace of legal challenges to the health law as well as ongoing congressional attempts to reach partisan agreement on a short-term budget bill to avert a government shutdown.

15 Mar 2011

Additional research needed for oral PrEP to treat HIV

The first human studies of an oral drug regimen to prevent HIV infection in high-risk individuals yielded a promising near 50% reduction in HIV incidence, but a number of issues require additional research before oral pre-exposure prophylaxis can be implemented on a large scale, according to an article in AIDS Patient Care and STDs, a peer-reviewed journal published by Mary Ann Liebert, Inc.

15 Mar 2011

AYA cancer patients require targeted care, say experts

Adolescents and young adults are neither children nor adults and those affected by cancer require targeted care that crosses the boundaries between pediatric and adult oncology, according to several pioneers in this still-developing field of adolescent and young adult oncology.

15 Mar 2011

Ingenuity announces new features to support RNA-Seq workflows, microRNA research in IPA

Ingenuity Systems, a leading provider of information and analytics solutions for life science researchers, today announced new features to support RNA-Sequencing workflows and microRNA research in IPA.

15 Mar 2011

ShangPharma fourth quarter net revenues increase 29.4% to $25.6 million

ShangPharma Corporation, a leading China-based pharmaceutical and biotechnology research and development outsourcing company, today announced its financial results for its fourth quarter and the fiscal year ended December 31, 2010.

15 Mar 2011

Medidata fourth quarter net revenue is $47.4 million for 2010

Medidata Solutions, a leading global provider of SaaS-based clinical technology solutions that enhance the efficiency of clinical development, today announced its financial results for the fourth quarter 2010 and full year ended December 31, 2010, as well as provided financial guidance for the first quarter and full year 2011.

15 Mar 2011

New research: Aging population triggers a boom in Chinese nursing home industry

A nursing home industry is booming in China as a rapid increase in the proportion of its elderly population forces a nationwide shift from traditional family care to institutional care, according to new research by Brown University gerontologists.

15 Mar 2011

InhibOx and COSMIC discoveries align to deliver full service drug discovery offering

InhibOx Ltd (spin-out of Oxford, UK) and the COSMIC Discoveries (the independent service arm of the Institute of Life Sciences, Hyderabad, India) today announce that they have formed a close strategic partnership to deliver a full service drug discovery service offering, incorporating expert computational, medicinal and synthetic chemistry design capabilities. Both commercial organizations, linked to world-leading academic institutes, have built their services on advanced proprietary science and technology. Together, they offer unique capabilities that are able to address the most demanding drug discovery challenges on behalf of biotech and pharmaceutical companies worldwide.

15 Mar 2011

Researchers discover new key component in lung cancer spread

Researchers discovered a new, key component in the spread of lung cancer as well as a likely way to block it with drugs now in clinical trial. The study was published today (Monday, March 14) in the Journal of Clinical Investigation.

15 Mar 2011

Documents show Blue Shield of Calif.'s rate increases could exceed 85%

Meanwhile, in Massachusetts, Blue Cross Blue Shield is under the microscope for its executive pay; and, in Colorado, some insurers are being pressed by consumer groups to offer rebates because of large cash surpluses.

15 Mar 2011

Type 2 diabetes drug less likely to cause weight gain, raise cholesterol levels

An inexpensive type 2 diabetes drug that has been around for more than 15 years works just as well and has fewer side effects than a half-dozen other, mostly newer and more expensive classes of medication used to control the chronic disease, new Johns Hopkins research suggests.

15 Mar 2011

Despite partisan clashes, political climate open to 'adult' budget debate

Media outlets report that no such serious discussion can be held without including entitlement programs such as Medicare, but public opinion continues to be a wildcard that could undermine momentum.

15 Mar 2011