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Pharmacological suppression of nonsense mutations effective in treating genetic defects

Genetic mutation can disrupt the way human cells make proteins, which in turn leads to inherited disease. David Bedwell, a professor in the University of Alabama at Birmingham (UAB) Department of Microbiology, says scientists are closer than ever to producing drugs that fix this disrupted-protein pathway and drastically improving treatment of genetic disease.

27 Apr 2010

High levels of phosphate in sodas accelerate signs of aging

Here's another reason to kick the soda habit. New research published online in the FASEB Journal shows that high levels of phosphates may add more "pop" to sodas and processed foods than once thought. That's because researchers found that the high levels of phosphates accelerate signs of aging. High phosphate levels may also increase the prevalence and severity of age-related complications, such as chronic kidney disease and cardiovascular calcification, and can also induce severe muscle and skin atrophy.

27 Apr 2010

Prime-boost malaria vaccine regimen provides sterile protection: Vical

Vical Incorporated announced today that a prime-boost malaria vaccine regimen provided sterile protection, with no disease symptoms and no detectable malaria parasites, in 4 of 15 vaccinated volunteers a full 28 days after challenge with multiple infected-mosquito bites.

27 Apr 2010

Researchers to commence enrolling participants in National Children's Study

After years of planning, UT Southwestern Medical Center researchers are ready to begin enrolling participants in the National Children's Study, which will examine the effects of environmental and genetic factors on child and adult health.

27 Apr 2010

Ashland reports 13% increase in sales from $1,990M to $2,248M for second-quarter 2010

For its 2010 second quarter, Ashland reported sales of $2,248 million, operating income of $151 million and net income of $22 million (27 cents per share). Net income was favorably affected by $2 million aftertax (2 cents per share) from discontinued operations. Cash flows provided by operating activities from continuing operations amounted to $183 million.

27 Apr 2010

Kinetic Concepts' first-quarter 2010 total revenues increase 3% to $485.8M

Kinetic Concepts, Inc. today reported first quarter 2010 total revenue of $485.8 million, an increase of 3% from the first quarter of 2009. Foreign currency exchange movements favorably impacted total revenue for the first quarter of 2010 by 2% compared to the corresponding period of the prior year.

27 Apr 2010

Illumina announces shipment of HiScanSQ system for research needs

Illumina, Inc. today announced shipment of HiScanSQ, the first instrument to integrate microarray analysis and next-generation sequencing in a modular design that can evolve with changing research needs.

From Illumina, Inc. 27 Apr 2010

European commission's FP7 programme allocated euro 6.10 billion

Europe is moving towards becoming a knowledge-based economy. Keeping in line with this objective, the European commission has instituted the Framework 7 (FP7) programme. Launched to support the re-launched Lisbon strategy, FP7 focuses on research themes rather than the framework programmes of the past. It has been designed to meet some of the persisting challenges of raising Europe to match global excellence in research, thereby benefiting the European life science funding.

27 Apr 2010

New imaging protocol to visualize activity of brain's reward circuitry in individuals addicted to drugs

Researchers at the U.S. Department of Energy's Brookhaven National Laboratory have developed an imaging protocol that allows them to visualize the activity of the brain's reward circuitry in both normal individuals and those addicted to drugs. The technique could lead to better insight into why people take recreational drugs as well as help determine which treatment strategies might be most effective.

27 Apr 2010

IBS patients treated with cognitive behavior therapy have positive response: Study

A significant proportion of irritable bowel syndrome patients treated with cognitive behavior therapy have a positive response within four weeks of treatment, according to a new study in Clinical Gastroenterology and Hepatology, the official journal of the American Gastroenterological Association Institute.

27 Apr 2010

Cell phone program to promote more physical activity

About two thirds of the American population is overweight or obese, putting them at higher risk for health problems such as heart disease, stroke, cancer and diabetes. The obesity epidemic in America is the result of poor eating habits, genetics, and a lack of exercise. It's therefore difficult for public health officials to get people to make a conscious effort to control their weight.

27 Apr 2010

Laughter increases production of antibodies and activates body's protective cells

Laughter is a highly complex process. Joyous or mirthful laughter is considered a positive stress (eustress) that involves complicated brain activities leading to a positive effect on health. Norman Cousins first suggested the idea that humor and the associated laughter can benefit a person's health in the 1970s. His ground-breaking work, as a layperson diagnosed with an autoimmune disease, documented his use of laughter in treating himself—with medical approval and oversight—into remission.

27 Apr 2010

Slitrk5 gene linked to development of OCD-like behaviors

Researchers at the Ansary Stem Cell Institute and the Department of Psychiatry at Weill Cornell Medical College discovered that mice missing a single gene developed repetitive obsessive-compulsive-like behaviors. The genetically altered mice, which behaved much like people with a certain type of obsessive-compulsive disorder (OCD), could help scientists design new therapies for this debilitating condition.

27 Apr 2010

Disadvantaged urban preschoolers more likely to struggle on playgrounds, athletic fields: Study

Disadvantaged urban preschoolers aren't only at risk for failure in the classroom - they are likely to struggle on playgrounds and athletic fields as well, research suggests.

27 Apr 2010

Medivir rights offering to raise approximately SEK 325 million

The Board of Directors has resolved on the terms for the rights offering, that the Board of Directors on 28 March 2010 resolved, subject to approval by the Annual General Meeting. For every share held in Medivir, regardless of share class, the holder is entitled to one subscription right. Four subscription rights entitle the holder to subscribe for one new class B share.

27 Apr 2010

Study links progression of lethal type of brain tumor with reduced expression of immune system genes

A new study links progression of a lethal type of brain tumor with reduced expression of more than 600 immune system genes, suggesting how complex the immune response is to the cancer and the resulting difficulty in targeting specific immune system proteins for treatment.

27 Apr 2010

CocE exhibits potential for clinical treatment of cocaine toxicity

Cocaine toxicity due to drug overdose results in more than half a million emergency room visits annually. Despite these alarming statistics, there is no Food and Drug Administration-approved pharmacotherapy specifically designed to treat cocaine toxicity. Emergency medical personnel are limited to treating only the immediate life-threatening symptoms of patients, while toxic levels of cocaine and its metabolic break-down products persist and continue to damage the cardiovascular system, liver and brain.

27 Apr 2010

Health care costs of abused women change from year to year after abuse ends: Study

Victims of domestic violence endure significantly higher health costs than other women for three years after the abuse ends, a new study finds.

27 Apr 2010

Advair to remain favored fixed-dose LABA/ICS combination therapy through 2013 for asthma and COPD

Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that, despite increased competition from several emerging agents, GlaxoSmithKline's Advair will remain surveyed pulmonologists' and primary care physicians' (PCPs) favored fixed-dose long-acting beta2 agonist (LABA)/inhaled corticosteroid (ICS) combination inhaler through 2013 for the treatment of asthma and chronic obstructive pulmonary disease (COPD).

27 Apr 2010

RENCI project to build easy-to-use tool to help doctors determine best treatment options for patients

Gersing is the mastermind behind MindLinc, a tool for managing, evaluating and improving behavioral health treatment used at Duke and in medical clinics across the U.S. MindLinc includes anonymous emergency medical record data accumulated from psychiatric patients over 20 years. As with any large data set, quickly analyzing data and translating the analysis into better patient care poses many challenges.

27 Apr 2010

Research News and Research

Pharmacological suppression of nonsense mutations effective in treating genetic defects

High levels of phosphate in sodas accelerate signs of aging

Prime-boost malaria vaccine regimen provides sterile protection: Vical

Researchers to commence enrolling participants in National Children's Study

Ashland reports 13% increase in sales from $1,990M to $2,248M for second-quarter 2010

Kinetic Concepts' first-quarter 2010 total revenues increase 3% to $485.8M

Illumina announces shipment of HiScanSQ system for research needs

European commission's FP7 programme allocated euro 6.10 billion

New imaging protocol to visualize activity of brain's reward circuitry in individuals addicted to drugs

IBS patients treated with cognitive behavior therapy have positive response: Study

Cell phone program to promote more physical activity

Laughter increases production of antibodies and activates body's protective cells

Slitrk5 gene linked to development of OCD-like behaviors

Disadvantaged urban preschoolers more likely to struggle on playgrounds, athletic fields: Study

Medivir rights offering to raise approximately SEK 325 million

Study links progression of lethal type of brain tumor with reduced expression of immune system genes

CocE exhibits potential for clinical treatment of cocaine toxicity

Health care costs of abused women change from year to year after abuse ends: Study

Advair to remain favored fixed-dose LABA/ICS combination therapy through 2013 for asthma and COPD

RENCI project to build easy-to-use tool to help doctors determine best treatment options for patients

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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