Serial Analysis of Gene Expression (SAGE) News and Research

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Study examines enrollment, use, and satisfaction with fee-for-service multispecialty system

Many physicians are adopting patient portals in response to governmental incentives for meaningful use (MU), but the stage 2 requirements for portal use may be particularly challenging for newer electronic health record (EHR) users.

25 Mar 2014

SAGE Therapeutics announces completion of $38 million Series C financing

SAGE Therapeutics, a biopharmaceutical company developing novel medicines to treat specialty, critical and orphan central nervous system (CNS) disorders, today announced the successful completion of a $38 million Series C financing. OrbiMed Advisors, LLC, EcoR1 Capital Management, Foresite Capital Management and two undisclosed blue chip public investment funds joined existing investors Third Rock Ventures and ARCH Venture Partners.

13 Mar 2014

Sutures embedded with stem cells led to quicker and stronger healing of Achilles tendon tears

Researchers have found that sutures embedded with stem cells led to quicker and stronger healing of Achilles tendon tears than traditional sutures, according to a new study published in the March 2014 issue of Foot & Ankle International (published by SAGE).

13 Mar 2014

Viewpoints: Ryan's attack on Medicaid; time to fix Medicare's doc pay

House Budget Committee Chairman Paul D. Ryan, R-Wis., obviously is a great adherent of the adage, "If at first you don't succeed, try, try again." On Monday his committee released another attack on Medicaid, one of the linchpins of the Affordable Care Act and one that for some reason is especially detested by conservatives, like the majority members of Ryan's committee (Michael Hiltzik, 3/3).

5 Mar 2014

Survival rates for bladder cancer in UK are falling, confirms new study

Of the top 10 cancers in the UK, bladder cancer is only one where survival rates have been shown to be getting worse. New figures published this month in the Journal of Clinical Urology confirm in a study of cases of bladder cancer in England over a 19 year period (from 1990 until 2009) that survival rates here in the UK are falling and are worse than in than in other European countries with similar incidence rates.

27 Feb 2014

Scotland achieves reduction in post-code lottery for hip replacement surgery

A reduction in the post-code lottery for hip replacement surgery has been achieved in Scotland without recourse to the private sector, according to new research published in the Journal of the Royal Society of Medicine.

26 Feb 2014

New research identifies raised risk of self-harm among patients with certain physical illnesses

New research quantifying the risk of admission to hospital for self-harm has identified a raised risk of self-harm among groups of patients with certain physical illnesses. While it is known that psychiatric illnesses are associated with a greatly elevated risk of self-harm, a moderately elevated risk was seen with common physical illnesses such as diabetes, epilepsy and asthma.

13 Feb 2014

$Sage Science releases new SageELF technology for DNA and protein fractionation$

Sage Science releases new SageELF technology for DNA and protein fractionation

Sage Science, a developer of products for improving sample preparation processes in life science applications, today announced the release of its new SageELF technology for DNA and protein fractionation. This sample prep instrument will be especially useful for preserving precious samples and has applications in next-generation sequencing as well as bottom-up or top-down proteomics experiments.

12 Feb 2014

Study shows at least 2M people in England could be eligible for bariatric surgery

Two million people in England could be eligible for weight loss surgery according to new research published today by JRSM Open, the open access companion publication of the Journal of the Royal Society of Medicine.

20 Jan 2014

At-home paper test can help spot early symptoms of cognitive issues

The Self-Administered Gerocognitive Examination (SAGE test), which takes less than 15 minutes to complete, is a reliable tool for evaluating cognitive abilities. Findings by researchers at The Ohio State University Wexner Medical Center confirming the feasibility and efficiency of the tool for community screening large numbers of people are published in the January issue of The Journal of Neuropsychiatry and Clinical Neurosciences.

13 Jan 2014

10 simple points to know and monitor alcohol intake

Much the same way individuals are encouraged to know their blood pressure and cholesterol numbers to maintain a healthy lifestyle, a new editorial in the Journal of Psychopharmacology urges the European public to know and monitor their alcohol intake number using a simple 10 point plan.

7 Jan 2014

Barriers persist to new approaches to medical liability, studies find

Issues of medical liability and tort reform, as well as how they interact with rising health care costs, continue to draw news media interest.

7 Jan 2014

Researchers identify a group of 39 genes linked with alcoholism

There is good evidence from studies of families and twins that genetics plays an important role in the development of alcoholism. However, hundreds of genes likely are involved in this complex disorder, with each variant contributing only a very small effect. Thus, identifying individual risk genes is difficult.

21 Nov 2013

Cancer research leaders announce the opening of ICGC-TCGA-DREAM SMC Challenge

Cancer research leaders from the Ontario Institute for Cancer Research and the University of California, Santa Cruz, in collaboration with Sage Bionetworks and IBM's DREAM, will announce tomorrow the opening of the ICGC-TCGA-DREAM Somatic Mutation Calling Challenge at the Sixth Annual RECOMB/ISCB conference.

8 Nov 2013

Left-handers more likely to suffer from psychotic disorders

Researchers have long studied the connections between hand dominance and different aspects of the human brain. A new study out today in SAGE Open finds that among those with mental illnesses, left-handers are more likely to suffer from psychotic disorders such as schizophrenia than mood disorders.

31 Oct 2013

Current drugs may harbor small-cell lung cancer promise

Scientists have identified several existing non-oncology drug classes that may have potential as a treatment for small-cell lung cancer, especially for patients with chemoresistant and metastatic disease.

28 Oct 2013

Bioengineers build novel tool to visualize protein networks from breast cancer cell data

A colorful wheel developed by Rice University bioengineers to visualize protein interactions has won an international competition for novel strategies to study the roots of breast cancer.

21 Oct 2013

SAGE Therapeutics obtains $20M Series B financing from two investors

SAGE Therapeutics, a biopharmaceutical company developing novel medicines to treat central nervous system (CNS) diseases, today announced a $20 million Series B financing from investors ARCH Venture Partners and Third Rock Ventures, bringing the total raised to $57.8 million since launch in 2011.

16 Oct 2013

Pan-Cancer Initiative: Patterns Emerge Across Diverse Tumor Types

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27 Sep 2013

New class of antidepressants appears potentially effective in combating deadly form of lung cancer

A little-used class of antidepressants appears potentially effective in combating a particularly deadly form of lung cancer, according to a new study from researchers at the Stanford University School of Medicine.

27 Sep 2013