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Is there an association between vitamin D, immunocompetence, and aging?

The role of an individual’s immunocompetence in the responsiveness to vitamin D.

1 Feb 2024

Rutgers researchers devise strategy to boost prostate cancer treatment efficacy

Rutgers researchers can predict which patients will benefit from a popular prostate cancer drug – and have devised a strategy that may make the treatment work longer.

22 Jan 2024

Scientists unveil the hidden respiratory mechanisms of gut bacteria

Study explores the use of respiratory electron acceptors by diverse gut bacteria, revealing a novel type of anaerobic respiration linked to the gut metabolome and microbial energy metabolism.

8 Jan 2024

IKAROS: Unlocking the secrets of the immune system's key player

In a scientific breakthrough that aids our understanding of the internal wiring of immune cells, researchers at Monash University in Australia have cracked the code behind IKAROS, an essential protein for immune cell development and protection against pathogens and cancer.

5 Jan 2024

Shedding new light on the hidden organization of the cytoplasm

Back in 2018, the lab of Christine Mayr, MD, PhD, at Memorial Sloan Kettering Cancer Center (MSK) introduced the world to a key cellular component that had been hiding in plain sight.

21 Dec 2023

D-alanine linked to gluconeogenesis in the kidney and circadian clock

Only recently was it discovered that amino acids, the building blocks of proteins, exist in two different forms: L- and D-forms.

21 Dec 2023

Single-cell RNA sequencing generates comprehensive atlas of zebrafish development

Researchers at the National Institutes of Health have published an atlas of zebrafish development, detailing the gene expression programs that are activated within nearly every cell type during the first five days of development, a period in which embryos mature from a single cell into distinct cell types.

18 Dec 2023

Wnt signaling holds promise for tailored immunotherapy in microsatellite-instable colorectal cancer

Colorectal cancer presents with varying clinical characteristics due to tumor heterogeneity. Microsatellite instability (MSI), present in 10%-15% of CRC cases, indicates a different clinical trajectory than microsatellite stable (MSS) patients.

15 Dec 2023

Organoid study opens new avenues in pulmonary neuroendocrine cancer therapy

Researchers performed a molecular analysis of neuroendocrine neoplasm (NEN) patient-derived tumor organoids (PDTOs) and their parental neoplasms.

13 Dec 2023

Breakthrough in pancreatic cancer treatment: Inhibiting specific enzymes slows tumor progression

Study demonstrates that inhibiting stromal class I histone deacetylases (HDACs) can effectively slow down pancreatic cancer progression, shedding light on a new therapeutic approach targeting the tumor microenvironment.

10 Dec 2023

Study sheds light on the molecular workings at play when oxygen exceeds normal levels

It only takes holding your breath for slightly too long to understand that too little oxygen is bad for you. But can you also have too much? Indeed, breathing air with a higher oxygen level than your body needs can cause health problems or even death.

8 Dec 2023

Study exploits biomolecular condensates to inhibit androgen receptor in prostate cancer

Transcription factors play essential roles in turning the genetic information encoded in genes into proteins in all cells and organisms.

5 Dec 2023

The effects of vitamin K on bone health

Existing scientific data on the effects of vitamin K (VK) on bone health and elucidated the underlying mechanisms.

30 Nov 2023

Omega-3s in the spotlight: The impact of EPA and DHA on athlete health and performance

Research paper reviews the effects of omega-3 fatty acids, EPA, and DHA, on athletes, discussing their benefits in inflammation control, cognitive function, and muscle maintenance, and the need for further research to fully understand their impact. It also addresses the risks and optimal intake of these supplements, highlighting their potential to improve athletic performance and recovery with minimal adverse effects at recommended doses.

27 Nov 2023

Transcription Factors News and Research

Is there an association between vitamin D, immunocompetence, and aging?

Rutgers researchers devise strategy to boost prostate cancer treatment efficacy

Scientists unveil the hidden respiratory mechanisms of gut bacteria

IKAROS: Unlocking the secrets of the immune system's key player

Shedding new light on the hidden organization of the cytoplasm

D-alanine linked to gluconeogenesis in the kidney and circadian clock

Single-cell RNA sequencing generates comprehensive atlas of zebrafish development

Wnt signaling holds promise for tailored immunotherapy in microsatellite-instable colorectal cancer

Organoid study opens new avenues in pulmonary neuroendocrine cancer therapy

Breakthrough in pancreatic cancer treatment: Inhibiting specific enzymes slows tumor progression

Study sheds light on the molecular workings at play when oxygen exceeds normal levels

Study exploits biomolecular condensates to inhibit androgen receptor in prostate cancer

The effects of vitamin K on bone health

Omega-3s in the spotlight: The impact of EPA and DHA on athlete health and performance

Scientists uncover key to enhancing cancer-killing T cells

New study links DNA methylation in GLP1R gene to obesity without metabolic disorders

Atlas of cancer's hidden rules: Unveiling the transcriptomic and epigenetic secrets across 11 tumors

Unsupervised genome-wide variant effect predictor based on pretraining of DNA language models

Precision oncology therapies account for nearly half of new cancer drug approvals since 1998

New method can help researchers map pancreatic cancer development

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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