VEGF News and Research

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VEGF is a substance made by cells that stimulates new blood vessel formation. Also called vascular endothelial growth factor.

Avastin study shows significant improvement in patients with metastatic colorectal cancer

Genentech, Inc. and Roche have announced that the New England Journal of Medicine published the first Phase III study of an anti-angiogenesis cancer therapy, showing that the addition of Avastin™ (bevacizumab) to the IFL chemotherapy regimen (5-FU/Leucovorin/ CPT-11) significantly extended survival in patients with first-line (previously untreated) metastatic colorectal cancer.

2 Jun 2004

Oxygen delivered through the nose may improve poor vision caused by diabetic macular edema

In a study of five diabetic patients with persistent macular edema, breathing supplemental oxygen for three months reduced fluid buildup and swelling in the macula and, in some cases, improved visual acuity. Researchers think the therapy could be used in conjunction with laser treatments that also improve oxygenation in the retina to provide long-term stability in these patients.

20 May 2004

Oxygen delivered through the nose may improve poor vision caused by diabetic macular edema

Oxygen delivered through the nose may improve poor vision caused by diabetic macular edema, fluid buildup in the part of the eye responsible for central vision, according to a pilot study by scientists at Johns Hopkins and the National Eye Institute.

18 May 2004

Australian company receives FDA orphan drug designation for product to treat malignant melanomas

Progen Industries Limited, an Australian anti-cancer drug development company, announced today that it has received orphan drug designation from the U.S. Food and Drug Administration (FDA) for their lead anti-angiogenesis product PI-88 for treatment of malignant melanoma.

3 May 2004

Researchers find drug that may suppress genetic mutation using a novel screening approach

Researchers at Massachusetts General Hospital have developed a way of identifying promising new drugs that may get around a major challenge in drug discovery.

18 Apr 2004

Diabetic retinopathy population will quadruple by 2012

Decision Resources, Inc., one of the world's leading research and advisory firms focusing on pharmaceutical and health care issues, finds that the drug-treated diabetic retinopathy population will quadruple by 2012.

12 Apr 2004

New treatment for heart attacks

A team led by scientists at The Scripps Research Institute has developed a potential new treatment for heart attacks. The therapy inhibits fluid leakage from cardiac blood vessels following a heart attack and thereby significantly prevents long-term heart damage and improves survival.

22 Mar 2004

VEGF News and Research

Further Reading

Avastin study shows significant improvement in patients with metastatic colorectal cancer

Oxygen delivered through the nose may improve poor vision caused by diabetic macular edema

Oxygen delivered through the nose may improve poor vision caused by diabetic macular edema

Australian company receives FDA orphan drug designation for product to treat malignant melanomas

Researchers find drug that may suppress genetic mutation using a novel screening approach

Diabetic retinopathy population will quadruple by 2012

New treatment for heart attacks

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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