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Researchers explore SARS-CoV-2 entry route and downstream cellular and viral processes

In a new study, researchers assessed the impact of the SARS-CoV-2 entry route on downstream cellular and viral processes.

10 Aug 2022

Gut microbiota-derived metabolites offer protection against SARS-CoV-2

A new study investigated how the gut microbiome confers immunity to mammalian hosts against SARS-CoV-2 intranasal infection by generating short-chain fatty acids.

5 Aug 2022

Scientists introduce SARS-CoV-2 phenotype screening for identifying novel antiviral drugs

Researchers introduced a phenotypic screening assay for identifying compounds with SARS-CoV-2 inhibition potential based on caspase 3/7 activation.

20 Jul 2022

Biotium introduces new line of antibodies for exosome detection

ExoBrite™ Antibody Conjugates are validated and optimized for bright and specific detection of exosome markers CD9, CD63, and CD81 for flow cytometry and western blotting.

20 Jul 2022

Patient-derived antibody cocktail active across SARS-CoV-2 variants of concern

In a recent study published in the journal Science Immunology, researchers in the United States described a rare anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) three antibody cocktail IMM-BCP-01.

4 Jul 2022

Recombinant SARS-CoV-2 harboring double reporters for COVID-19 surveillance

In a recent article posted to the bioRxiv* preprint server, researchers at Texas Biomedical Research Institute, Georgia State University, and the University of Alabama at Birmingham developed a bireporter-expressing recombinant severe acute respiratory syndrome coronavirus 2 (rSARS-CoV-2) for tracking SARS-CoV-2 infection.

27 Jun 2022

Chemical synthesis, properties, and molecular modeling studies of spiro-indole compounds

In a recent study under review at the Scientific Reports journal and currently posted to the Research Square* preprint server, researchers synthesized and evaluated the antitumoral (against several cancer cell lines) and antiviral [against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)] properties of 3-spiro-indolin-2-ones.

15 Jun 2022

SARS-CoV-2 damages cilia

Researchers determine whether the interaction between ORF10 and ZYG11B promotes the dissemination of SARS-CoV-2.

15 Jun 2022

SARS-CoV-2 mRNA vaccines do not stimulate interferon stimulatory gene expression in Aicardi Goutières Syndrome patients

A new study aimed to evaluate the immunostimulatory potential of mRNA vaccines in AGS patients.

23 May 2022

Camelid IFNs could play important role in combating emerging zoonotic pathogens

In a recent study published in the Developmental & Comparative Immunology journal, the discovery of a novel form of mammalian interferon-Beta (IFN-β) with four cysteine residues from the dromedary camel and the five remaining members of the mammalian suborder Tylopoda is described.

17 May 2022

Neutralization of SARS-CoV-2 by plant-made neutralizing monoclonal antibodies

In a recent study published in the journal Vaccines, researchers developed plant-based monoclonal antibodies (mAbs) against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).

17 May 2022

Study explores macromolecular viral entry inhibitors as broad-spectrum first-line antivirals with anti-SARS-CoV-2 activities

Researchers created polystyrene sulfonate with significantly different molar masses, constructed these polymers as an exterior around spherical gold nanoparticles of various sizes to improve multivalency effects, measured antiviral effects of the antivirals on numerous viruses in vitro, and investigated the method of interaction of the leads with SARS-CoV-2 and lentiviral particles.

13 May 2022

SARS-CoV-2 N-terminal domain modulates S1/S2 cleavage and spike-mediated functions

In a recent study posted to the bioRxiv* preprint server, researchers explored the role of the N-terminal domain (NTD) of the severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) spike (S) protein in SARS-CoV-2 fusion with the host membranes and coronavirus disease 2019 (COVID-19).

12 May 2022

Western Blot News and Research

Researchers explore SARS-CoV-2 entry route and downstream cellular and viral processes

Gut microbiota-derived metabolites offer protection against SARS-CoV-2

Scientists introduce SARS-CoV-2 phenotype screening for identifying novel antiviral drugs

Biotium introduces new line of antibodies for exosome detection

Patient-derived antibody cocktail active across SARS-CoV-2 variants of concern

Recombinant SARS-CoV-2 harboring double reporters for COVID-19 surveillance

Chemical synthesis, properties, and molecular modeling studies of spiro-indole compounds

SARS-CoV-2 damages cilia

SARS-CoV-2 mRNA vaccines do not stimulate interferon stimulatory gene expression in Aicardi Goutières Syndrome patients

Camelid IFNs could play important role in combating emerging zoonotic pathogens

Neutralization of SARS-CoV-2 by plant-made neutralizing monoclonal antibodies

Study explores macromolecular viral entry inhibitors as broad-spectrum first-line antivirals with anti-SARS-CoV-2 activities

SARS-CoV-2 N-terminal domain modulates S1/S2 cleavage and spike-mediated functions

An Ad5 vectored COVID vaccine expressing an S1-N fusion protein

Research looks at potential of pantethine against SARS-CoV-2

Study investigates stress granule formation during infection with the human common cold coronavirus and SARS-CoV-2

Proximity labeling to identify high-confidence SARS-CoV-2 interactors

Multivalent messenger ribonucleic acid-lipid nanoparticle vaccines against SARS-CoV-2

Features of SARS-CoV-2 Omicron BA.2 sublineage spike protein

Study explores SARS-CoV-2 Omicron variant and infected colon epithelial cells

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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