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Inhibiting proteins may prevent cartilage breakdown in arthritis patients

Current arthritis medications can ease the pain, but stopping the progression of the disease requires more aggressive treatments: use of very limited available drugs or surgical intervention.

20 Feb 2009

Forgotten and lost -- when proteins 'shut down' our brain

Which modules of the tau protein, in neurons of Alzheimer disease patients, may act in a destructive manner were investigated by researchers from the Max Planck Institute for Biophysical Chemistry (Göttingen) and the Max Planck Unit for Structural Molecular Biology (Hamburg) with the help of Nuclear Magnetic Resonance Spectroscopy ( PLoS Biology , February 17, 2009).

18 Feb 2009

X-ray eyes bring us closer to early diagnosis of Parkinson's disease

It is estimated that 4 million people world-wide are suffering from Parkinson's, a complex disease that varies greatly among affected individuals.

17 Feb 2009

Video imaging technique provides dynamic view of airway obstruction

A video imaging technique demonstrates that the soft palate, the tissue at the back of the roof of the mouth, is more elongated and angled in patients with obstructive sleep apnea both when they sleep and when they are awake, according to a report in the February issue of Archives of Otolaryngology-Head & Neck Surgery.

17 Feb 2009

Groundbreaking study reveals how enzymes in the cell cooperate to make fat

These enzymes are integrated into a single molecular complex known as fatty acid synthase. This complex is regarded as a potential target for developing new anti-obesity and anti-cancer drugs.

11 Feb 2009

Long-sought protein structure may help reveal how ‘gene switch’ works

The bacterium behind one of mankind's deadliest scourges, tuberculosis, is helping researchers at the Commerce Department's National Institute of Standards and Technology (NIST) and the Department of Energy's Brookhaven National Laboratory (BNL) move closer to answering the decades-old question of what controls the switching on and off of genes that carry out all of life's functions.

10 Feb 2009

New microscope visualizes cells in 3D

University of Washington researchers have helped develop a new kind of microscope to visualize cells in three dimensions, an advance that could bring great progress in the field of early cancer detection.

9 Feb 2009

Long-sought protein structure may help reveal how 'gene switch' works

8 Feb 2009

Discovery of important drug target for influenza

Influenza is and remains a disease to reckon with. Seasonal epidemics around the world kill several hundred thousand people every year.

5 Feb 2009

Measurement of kidney function in children with kidney disease improved

A formula used to measure kidney function in children with chronic kidney disease has been revised to make it more precise, according to a study published today in the Journal of the American Society of Nephrology.

21 Jan 2009

Aribex awarded patents for NOMAD handheld X-ray system

Aribex, Inc. has announced that it has been allowed a second U.S. patent for its NOMAD Handheld X-ray System.

19 Jan 2009

MRSA's weak point visualised by scientists

An enzyme that lives in Methicillin-resistant Staphylococcus aureus (MRSA) and helps the dangerous bacterium to grow and spread infection through the human body has been visualised for the first time, according to a study out today in Proceedings of the National Academy of Sciences (PNAS).

19 Jan 2009

E. coli persists against antibiotics through HipA-induced dormancy

Bacteria hunker down and survive antibiotic attack when a protein flips a chemical switch that throws them into a dormant state until treatment abates, researchers at The University of Texas M. D. Anderson Cancer Center report in the Jan.16 edition of Science.

19 Jan 2009

Researchers solve structure of key Ebola protein

Research led by Iowa State University scientists has them a step closer to finding a way to counter the Ebola virus.

12 Jan 2009

Discovery of 'on switch' for cell death signaling mechanism

Scientists at Burnham Institute for Medical Research (Burnham) have determined the structure of the interactions between proteins that form the heart of the death inducing signaling complex (DISC), which is responsible for triggering apoptosis (programmed cell death).

5 Jan 2009

Molecular imaging enables earlier, individualized treatment of thyroid cancer

In a study to determine the diagnostic value of molecular imaging in nodal staging of patients with thyroid cancer, researchers were able for the first time to accurately distinguish between cancerous cells in regional lymph nodes and normal residual thyroid tissue directly after surgery.

5 Jan 2009

New online tool for calculating colorectal cancer risk

A new online tool for calculating colorectal cancer risk in men and women age 50 or older was launched today, based on a new risk-assessment model developed by researchers at the National Cancer Institute (NCI), part of the National Institutes of Health.

1 Jan 2009

Researchers identify clockwork that drives a powerful virus nanomotor

Peering at structures only atoms across, researchers have identified the clockwork that drives a powerful virus nanomotor.

30 Dec 2008

Early photon tomography provides clearer picture of tumors in living animals

Fluorescent molecules - i.e. substances which can be stimulated to emit light - are extremely valuable tools in biological research and medical diagnosis.

10 Dec 2008

FDA grants compassionate case for use of novel wet age-related macular degeneration treatment

NeoVista, Inc., announced today that the U.S. Food and Drug Administration (FDA) had approved the company's "compassionate case" waiver to utilize its novel wet age-related macular degeneration (AMD) treatment on a patient with an advanced form of the disease who did not meet criteria for inclusion into current NeoVista investigational treatment protocols.

10 Dec 2008