DispenseSix™ has changed titration preparation, making it effortless and touch-free. Its integrated RFID technology instantly identifies four reagents, while a 120,000-step piston accurately dispenses volumes ranging from 10 μL to 500 mL, adhering to ISO 8655-3 standards through a 45 μL flow path that prevents carry-over.
When connected to METTLER TOLEDO titrators or LabX™, it enhances workflow efficiency, mitigates transcription errors, and allows analysts to focus on more valuable tasks and insights.
Productive workflows: Streamlines the preparation of samples, aliquoting, and the creation of four-solvent dilution series in a single OneClick™ run.
Exact volumes: A resolution of 120,000 steps ensures ISO-certified dosing ranging from 10 μL to 500 mL without the need for recalibration.
Plug and play: RFID technology stores information on liquid identifiers, batches, and expiration dates, enabling the exchange of bottles within seconds without setup errors.
Powerful design: PVDF/PTFE wetted components are resistant to harsh acids, bases, and solvents; the snap-apart head allows for quick cleaning.
Highlight
One-click dilution series with DispenSix
Observe the collaboration of T7/T9 Excellence, DispenSix, and an InMotionTM autosampler: the liquid handler performs rinsing, aspiration, and dispensing of up to four liquids, followed by automatic cleaning between steps to create a four-point dilution series, ensuring accurate and traceable results without manual pipetting.
DispenSix - Automated Liquid Handler for Titration
Productive workflows
Image Credit: Mettler Toledo – Titration Systems
Multi-liquid: Delivers a maximum of four reagents for preparation, aliquoting, and dilution in a single operation.
Autosampler: Compatible with InMotion racks to handle over 300 beakers entirely without supervision.
LabX: RFID activates the appropriate method, eliminating the need for manual selection and cut-and-paste procedures.
Accurate and precise
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Resolution: The 120,000-step piston provides a delivery range of 10 μL to 500 mL, ensuring compliance with ISO 8655-3 standards.
Carry-over: < 45 μL dead volume protects the results from cross-contamination.
Traceability: Every dispense is recorded in LabX to ensure repeatability and provide audit proof.
Plug and play
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RFID: The built-in tag automatically identifies liquids and promptly loads their parameters.
OneClick™: Initiate dispensing, titration, and cleaning with a single tap on a titrator or LabX.
Fast swap: Switch solvents in mere seconds, without the need for recalibration or resetting the tubing.
Powerful design
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Materials: The flow path made of PVDF/PTFE is capable of enduring severe acids, bases, and solvents.
Maintenance: Disassembly without tools, along with scheduled rinses, ensures that downtime remains minimal.
Longevity: Designed to endure millions of cycles to satisfy 24/7 quality control requirements
DispenSix automation for titration
Image Credit: Mettler Toledo – Titration Systems
Automated liquid handling, DispenSix ecosystem
The DispenSix liquid handler transforms any T7/T9 Excellence titrator into a completely automated workstation. Its six-port head and dDrive motor deliver doses ranging from 10 μL to 500 mL with ISO 8655-3 precision, while RFID technology ensures error-free solvent exchanges. When combined with InMotion autosamplers and LabX software, it enables unattended dilution series, provides traceable audit trails, and ensures continuous productivity.
DispenSix liquid handler
Image Credit: Mettler Toledo – Titration Systems
Replace manual pipetting with the precision of a push-button system: DispenSix automates the addition of reagents, serial dilutions, and aliquots ranging from 10 μL to 500 mL, using RFID-verified chemistries. This significantly reduces preparation time and errors while ensuring complete traceability.
Titrator excellence T7
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T7 Adaptable Workhorse: DispenSix automates preparation, accommodating up to four burettes and featuring an additional sensor board to facilitate potentiometric and KF titrations. Furthermore, a straightforward upgrade option to T9 ensures the protection of future budgets.
Titrator excellence T9
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Peak productivity: The T9 operates the DispenSix and InMotion autosamplers simultaneously, performs dual titrations concurrently, and executes high-volume quality control batches for pharmaceuticals, polymers, or food at twice the speed while ensuring LabX compliance.
InMotion Flex | Pro | Max:
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Queues 11-303 samples; PowerShower™ cleaning, and DispenSix for continuous, contamination-free titration processes.
InMotion KF autosampler
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Heats 26 sealed vials; Temperature Scan, along with DispenSix, delivers unattended, trace-level moisture results for each batch.
Titration Software LabX
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LabX Software enhances laboratory operations by streamlining workflows, increasing efficiency, and facilitating compliance.
SmartChemicals, RFID-tagged accuracy and walk-up convenience
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Certified potency – Factory-standardized titrants are delivered with ISO 17025 documentation, ensuring audit-proof and repeatable results.
Scan and dispense – Secure the bottle; DispenSix scans the SmartChemical tags and promptly loads the lot number, concentration, and expiration date.
On-demand dilutions – Use concentrates and allow DispenSix to automatically generate effective solutions, thereby reducing storage, waste, and expenses.
Take automation to the next level
Start with InMotion autosamplers – Flex, Pro, or Max can queue a maximum of 303 samples. Include DispenSix only when pipetting or dilution needs to be conducted entirely without supervision.
ABB Robotics joins forces with METTLER TOLEDO to accelerate the global adoption of lab automation
Add smart pumps and solvent manager – The automated delivery of reagents and the removal of waste ensure that titrators remain adequately supplied while keeping operators safe from potential hazards.
Step up to ABB collaborative robots – Collaborative robots weigh, uncap, load racks, and deliver them to the autosampler, facilitating genuine 24/7 lights-out throughput.
Clone workflows anywhere – Export LabX "digital-twin" files to replicate validated methods from one site to another, ensuring global consistency and facilitating rapid return on investment.
Application spotlight
Automated Fluoride ISE analysis with DispenSix
Image Credit: Mettler Toledo – Titration Systems
The DispenSix liquid handler automatically prepares fluoride standards ranging from one to 1000 ppm. Afterward, the T7/T9 titrator and perfectIONF-ISE accurately quantify samples without any carryover. This automated workflow enhances precision, eliminates pipetting errors, and directly records results into LabX.
Dose-range linearity verification
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Ensure precise dosing within 10-90 % of the 50 mL range: DispenSix pairs with T7/T9 and an InMotion rack to dispense NaOH/TRIS samples, conduct HCl titrations, and automatically compute slope / R2 for GMP-compliant verification.
Lithium hydroxide purity check
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Automate the determination of LiOH and Li2CO3 for battery-grade powders: DispenSix effectively shields hygroscopic samples from CO2, dispenses accurate aliquots, and performs T7/T9 titrations using HCl. This single step provides reliable percentage results, traces of carbonate, and documentation that is compliant with GMP standards.
Automated pH, acidity, and sulfite testing in vinegar and wine
Image Credit: Mettler Toledo – Titration Systems
The Six-port DispenSix, in conjunction with an InMotion rack and T7/T9 titrator, automates the processes of reagent addition, sample dosing, and dual titrations to provide measurements of pH, acetic acid, and free SO2 in a single run – achieving a <3 % RSD for dependable quality control in beverages.
Automated kappa number for pulp quality
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Redox back-titration utilizing permanganate/thiosulfate is conducted on an InMotion autosampler in conjunction with a DispenSix liquid handler, adhering to ISO 302 standards to measure lignin and chemical demand in pulp. Accurate dosing, blank correction, and LabX calculations ensure consistent Kappa numbers for process optimization.