Genetics News and Research

Latest Genetics News and Research

Liverpool scientists complete genomics studies on multidrug resistant Typhoid fever in Africa

The team has completed two genomics studies on the tropical disease, a condition that is estimated to cause up to 30 million illnesses and over a quarter of a million deaths globally each year.

27 May 2015

UVA scientists find blueprint for combating human disease using DNA clad in near-indestructible armor

By unlocking the secrets of a bizarre virus that survives in nearly boiling acid, scientists at the University of Virginia School of Medicine have found a blueprint for battling human disease using DNA clad in near-indestructible armor.

27 May 2015

Study reveals molecular basis for endocrine therapy-resistant breast cancer

Mitsuyoshi Nakao, Director of the Institute of Molecular Embryology and Genetics in Kumamoto University and Associate Professor Noriko Saitoh revealed that a cluster of defined, non-coding RNAs are mechanistically involved in endocrine therapy resistance in human breast cancer cells. Furthermore, resveratrol, a kind of polyphenol, was found to repress these RNAs and inhibit the proliferative activity of breast cancer cells which had acquired resistance.

27 May 2015

Removing accumulated mutant p53 protein regresses tumors, increases cancer survival

Removing accumulated mutant p53 protein from a cancer model showed that tumors regress significantly and survival increases. This finding, by an international team of cancer researchers led by Ute Moll, MD, Professor of Pathology at Stony Brook University School of Medicine, is reported in a paper published advanced online May 25 in Nature.

26 May 2015

Researchers discover new gene subgroup that drives prostate cancer

Prostate cancer researchers have drawn a molecular portrait that provides the first complete picture of localized, multi-focal disease within the prostate and also unveils a new gene subgroup driving it.

26 May 2015

Essential fatty acids play crucial role in human brain growth and function

New research conducted in a rural community in Pakistan highlights the crucial role that essential fatty acids play in human brain growth and function.

26 May 2015

Researchers identify gene vital to production of pain-sensing neurons in humans

A gene essential to the production of pain-sensing neurons in humans has been identified by an international team of researchers co-led by the University of Cambridge. The discovery, reported today in the journal Nature Genetics, could have implications for the development of new methods of pain relief.

26 May 2015

Scientists uncover role of HTRA3 protease in Cockayne syndrome

Scientists from the Institut Pasteur and CNRS, in collaboration with scientists from the Institut Gustave Roussy and CEA, have succeeded in restoring normal activity in cells isolated from patients with the premature aging disease Cockayne syndrome. They have uncovered the role played in these cells by an enzyme, the HTRA3 protease.

22 May 2015

Aptensio XR once-daily treatment for ADHD to be available in Summer 2015

Today, Rhodes Pharmaceuticals L.P. announced that Aptensio XR, a once-daily central nervous system stimulant indicated for the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) will be available to patients beginning Summer 2015.

22 May 2015

Sex-determining gene in mosquitoes may help reduce disease transmission

Researchers with the Fralin Life Science Institute at Virginia Tech have identified a gene responsible for sex determination in mosquitoes that can transmit yellow fever, dengue, and chikungunya viruses.

22 May 2015

First-of-its-kind DNA bank aims at advancing research into genetics of stuttering

Scientists at the University of Alberta's Institute for Stuttering Treatment and Research want Albertans to give a spit -- five millilitres to be precise -- to help find the cause and a cure for stuttering.

21 May 2015

Scientists reveal how lymphatic system develops in embryo

For over one hundred years, scientists have debated the question of the origins of the lymphatic system - a parallel system to the blood vessels that serves as a conduit for everything from immune cells to fat molecules to cancer cells. This issue has now been resolved by Dr. Karina Yaniv of Weizmann Institute's Biological Regulation Department. In a study reported online today in Nature, she and her team revealed how the lymphatic system develops in the embryo and for the first time managed to grow lymphatic cells in the lab.

21 May 2015

New study suggests ways to accelerate recovery from dangerous diarrheal disease

A new study delineates a sequential pattern of changes in the intestinal microbial population of patients recovering from cholera in Bangladesh, findings that may point to ways of speeding recovery from the dangerous diarrheal disease.

20 May 2015

Severe OSA, excessive daytime sleepiness linked to increased risk of depression in men

Severe obstructive sleep apnea (OSA) and excessive daytime sleepiness are associated with an increased risk of depression in men, according to a new community-based study of Australian men, which was presented at the 2015 American Thoracic Society International Conference.

19 May 2015

Study finds new colon cancer screening as promising alternative to colonoscopy for African Americans

In a first-of-its-kind clinical trial, physician-scientists at University Hospitals Case Medical Center Seidman Cancer Center and Case Western Reserve University School of Medicine found that a new non-invasive technology for colon cancer screening is a promising alternative to colonoscopy for African Americans.

19 May 2015

UTHealth receives supplemental grant to establish Biosafety and Infectious Disease Training Initiative

Researchers from The University of Texas Health Science Center at Houston School of Public Health have received a $100,000 supplemental grant from the National Institute of Environmental Health Sciences to establish a Biosafety and Infectious Disease Training Initiative.

19 May 2015

Alnylam files clinical trial application for alpha-1 liver disease, presents data at DDW

Alnylam Pharmaceuticals, Inc. has announced that it has filed a Clinical Trial Application (CTA) with the U.K. Medicines and Healthcare products Regulatory Agency (MHRA) to initiate a Phase 1/2 clinical trial with ALN-AAT, a subcutaneously administered investigational RNAi therapeutic targeting alpha-1 antitrypsin (AAT) for the treatment of AAT deficiency-associated liver disease (alpha-1 liver disease).

19 May 2015

Too much or too little sleep may up stroke risk in hypertensive patients

High blood pressure, or hypertension, affects one third of--or 70 million--US adults, and the healthcare costs associated with treating the disease are approximately $46 billion.

18 May 2015

Study compares effectiveness of treatments for metastatic non-clear cell kidney cancers

A head-to-head comparison of two biologic therapies used to treat a subset of patients with advanced kidney cancers provides much-needed clarity on the preferred treatment for the first line of attack.

15 May 2015

New genomics laboratory in Liberia enables scientists to monitor genetic changes in Ebola virus

Army scientists working to support the Ebola virus outbreak response in West Africa have established the first genomic surveillance capability in Liberia, enabling them to monitor genetic changes in the virus within one week of sample collection. An article describing their work was recently published ahead of print in the online edition of Emerging Infectious Diseases.

15 May 2015

Genetics News and Research

Latest Genetics News and Research

Liverpool scientists complete genomics studies on multidrug resistant Typhoid fever in Africa

UVA scientists find blueprint for combating human disease using DNA clad in near-indestructible armor

Study reveals molecular basis for endocrine therapy-resistant breast cancer

Removing accumulated mutant p53 protein regresses tumors, increases cancer survival

Researchers discover new gene subgroup that drives prostate cancer

Essential fatty acids play crucial role in human brain growth and function

Researchers identify gene vital to production of pain-sensing neurons in humans

Scientists uncover role of HTRA3 protease in Cockayne syndrome

Aptensio XR once-daily treatment for ADHD to be available in Summer 2015

Sex-determining gene in mosquitoes may help reduce disease transmission

First-of-its-kind DNA bank aims at advancing research into genetics of stuttering

Scientists reveal how lymphatic system develops in embryo

New study suggests ways to accelerate recovery from dangerous diarrheal disease

Severe OSA, excessive daytime sleepiness linked to increased risk of depression in men

Study finds new colon cancer screening as promising alternative to colonoscopy for African Americans

UTHealth receives supplemental grant to establish Biosafety and Infectious Disease Training Initiative

Alnylam files clinical trial application for alpha-1 liver disease, presents data at DDW

Too much or too little sleep may up stroke risk in hypertensive patients

Study compares effectiveness of treatments for metastatic non-clear cell kidney cancers

New genomics laboratory in Liberia enables scientists to monitor genetic changes in Ebola virus

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging