Drug Delivery News and Research

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Drug delivery is a term that refers to the delivery of a pharmaceutical compound into the body. Most common methods of delivery include the preferred non-invasive oral (through the mouth), nasal, pneumonial (inhalation), and rectal routes. Much research is now focussing on nanotechnology as a drug delivery method.

Emisphere second-quarter net loss increases to $13.7 million

Emisphere Technologies, Inc. today announced financial and operational results for the three and six months ended June 30, 2010.

16 Aug 2010

Titan Pharmaceuticals second-quarter net loss increases to $1.84 million

Titan Pharmaceuticals, Inc. today reported financial results for the second quarter ended June 30, 2010.

16 Aug 2010

A.P. Pharma second quarter 2010 net loss decreases to $0.09 per share

A.P. Pharma, Inc., a specialty pharmaceutical company, today reported financial results for its second quarter ended June 30, 2010.“We are working expeditiously to complete the work needed to prepare for a meeting with the FDA. Once the necessary information is available, we will request an End of Review meeting to discuss the next steps for the APF530 New Drug Application.”

16 Aug 2010

New T cell engineering approach can improve success rate of immune-cell therapies

Clinical trials using patients' own immune cells to target tumors have yielded promising results. However, this approach usually works only if the patients also receive large doses of drugs designed to help immune cells multiply rapidly, and those drugs have life-threatening side effects. Now a team of MIT engineers has devised a way to deliver the necessary drugs by smuggling them on the backs of the cells sent in to fight the tumor. That way, the drugs reach only their intended targets, greatly reducing the risk to the patient.

16 Aug 2010

Researchers develop screening tool to observe nanoparticle reaction inside the body

Researchers at North Carolina State University have developed a method for predicting the ways nanoparticles will interact with biological systems - including the human body. Their work could have implications for improved human and environmental safety in the handling of nanomaterials, as well as applications for drug delivery.

16 Aug 2010

Soligenix’s net loss for second-quarter 2010 decreases to $1,577,000

Soligenix, Inc., a late-stage biopharmaceutical company, announced today its financial results for the second quarter of 2010.

13 Aug 2010

Researchers develop new implantable metamaterials to destroy cancerous tissue

The research, reported online July 21, 2010, in the journal Advanced Materials, provides a promising path towards the development of a new class of metamaterial-inspired implantable biosensors and biodetectors.Metamaterials are artificial electromagnetic composites, typically made of highly conducting metals, whose structures respond to electromagnetic waves in ways that atoms in natural materials do not. The most futuristic metamaterials would absorb all light, to create heat to destroy cancerous tissue, or bend light completely around an object, rendering that object invisible-an imaginary delight for fans of science fiction or spy novels.

13 Aug 2010

Halozyme Therapeutics granted U.S. patent for recombinant human hyaluronidase enzyme platform

Halozyme Therapeutics, Inc. today announced the issuance of U.S. Patent No. 7,767,429 claiming its proprietary recombinant human hyaluronidase enzyme platform (rHuPH20). Claims to the human PH20 glycoprotein, PEGylated variants, the glycoprotein produced by recombinant methods, and pharmaceutical compositions with other agents, including antibodies, insulins, cytokines, anti-infectives and additional therapeutic classes were awarded in the '429 patent. Additional claims are in prosecution.

12 Aug 2010

Labopharm second-quarter total revenue increases to $6.8 million

Labopharm Inc. today reported its financial results for the second quarter and first six months ended June 30, 2010. All figures are in Canadian dollars unless otherwise stated.

12 Aug 2010

NextWave Pharmaceuticals, Tris Pharma sign agreement to enhance CNS product portfolio

NextWave Pharmaceuticals and Tris Pharma, both privately held companies, announced a new collaboration agreement to enhance NextWave's CNS product portfolio utilizing Tris Pharma's unique drug delivery technology for liquid and solid formulations. Tris has reacquired the rights to non CNS products including all the OTC products previously licensed to NextWave Pharmaceuticals.

12 Aug 2010

Dicerna announces closing of $25 million Series B round of financing

Dicerna Pharmaceuticals, Inc., a second generation RNA interference company developing novel therapeutics utilizing its proprietary Dicer Substrate Technology™ and Dicer Substrate siRNA molecules, today announced that it has closed a $25 million Series B round of financing. New investor Domain Associates led the round, with all existing investors participating - Oxford Bioscience Partners, Skyline Ventures and Abingworth.

11 Aug 2010

InspireMD announces availability of new delivery system for MGuard stent

InspireMD Ltd. is announcing today the availability of a new and improved delivery system for its MGuard coronary stent system. The new delivery system, which has already been introduced in selected regions around the world, will now make its launch in South America during SOLACI 2010, taking place at the Hilton Hotel in Buenos Aires, Argentina, August 11th-13th.

11 Aug 2010

Rxi Pharmaceuticals second-quarter net loss decreases to $2.1 million

RXi Pharmaceuticals Corporation, a recognized leader in RNAi-based therapeutic discovery and development, today reported its financial results for the second quarter ended June 30, 2010.

11 Aug 2010

Agile initiates Phase 3 NEW CHOICE Study of AG200-15 contraceptive patch

Agile Therapeutics, Inc., a pharmaceutical development company specializing in women's healthcare products, today announced study initiation and dosing of the first patient in the Company's pivotal, Phase 3 NEW CHOICE Study of AG200-15, Agile's lead contraceptive patch. AG200-15 is designed to effectively deliver a low dose of estrogen in combination with levonorgestrel. The patch is applied once weekly for three weeks followed by a patch-free week.

11 Aug 2010

Depomed announces SPA agreement with FDA for Serada Phase 3 trial for menopausal hot flashes

Depomed, Inc. announced today that it has reached agreement with the U.S. Food and Drug Administration regarding a Special Protocol Assessment on the design and analysis of Breeze 3, a Phase 3 trial evaluating Serada® (extended release gabapentin tablets) for menopausal hot flashes.

11 Aug 2010

OptiNose's bi-directional nasal device delivering fluticasone effective in reducing nasal polyps in CRS patients

OptiNose Inc. announced today that a subgroup analysis of positive Phase II trial results has been published in the July/August issue of the American Journal of Rhinology & Allergy.

11 Aug 2010

Elan to offer $200 million in aggregate principal amount of 8.75% senior notes due 2016

Elan Corporation, plc today announced that its wholly-owned subsidiaries, Elan Finance public limited company and Elan Finance Corp., intend to offer, subject to market conditions, US$200 million in aggregate principal amount of 8.75% senior notes due 2016.

11 Aug 2010

Sinobiopharma inks agreement with Lianhuan to co-develop, manufacture and commercialize Eplerenone

Sinobiopharma, Inc., an innovative biopharmaceutical products company with primary operations in China, today announced that the Company, through its wholly-owned subsidiary Dong Ying Pharmaceutical Co., Ltd., has signed an agreement with Jiangsu Lianhuan Pharmaceuticals Co., Ltd. to co-develop, manufacture and commercialize Eplerenone, a therapeutic agent formulated to treat high blood pressure and vascular diseases.

11 Aug 2010

Columbia Laboratories announces repurchase of 3.3 million common stock

Columbia Laboratories, Inc. has repurchased 3,333,330 shares of its Common Stock, par value $0.01 per share, from investment funds for which Perry Corp. or an affiliate acts as investment advisor and/or general partner at $0.90 per share for an aggregate total purchase price of approximately $3 million. This transaction reduces the total issued and outstanding shares of Common Stock by about 4% from approximately 84.1 million to 80.8 million. This transaction also reduces the Company's previously forecast 2010 year-end cash balance to approximately $20 million.

11 Aug 2010

Scientists develop new method to enable drug release inside cancer cells

Scientists from UCLA's California NanoSystems Institute and Korea's Yonsei University have developed an innovative method that enables nanomachines to release drugs inside living cancer cells when activated remotely by an oscillating magnetic field.The new system - the first to utilize a class of porous nanomaterials driven by a magnetic core - has the potential to improve both targeted drug-delivery and magnetic resonance imaging in the treatment of cancer and other diseases.

11 Aug 2010

Drug Delivery News and Research

Further Reading

Emisphere second-quarter net loss increases to $13.7 million

Titan Pharmaceuticals second-quarter net loss increases to $1.84 million

A.P. Pharma second quarter 2010 net loss decreases to $0.09 per share

New T cell engineering approach can improve success rate of immune-cell therapies

Researchers develop screening tool to observe nanoparticle reaction inside the body

Soligenix’s net loss for second-quarter 2010 decreases to $1,577,000

Researchers develop new implantable metamaterials to destroy cancerous tissue

Halozyme Therapeutics granted U.S. patent for recombinant human hyaluronidase enzyme platform

Labopharm second-quarter total revenue increases to $6.8 million

NextWave Pharmaceuticals, Tris Pharma sign agreement to enhance CNS product portfolio

Dicerna announces closing of $25 million Series B round of financing

InspireMD announces availability of new delivery system for MGuard stent

Rxi Pharmaceuticals second-quarter net loss decreases to $2.1 million

Agile initiates Phase 3 NEW CHOICE Study of AG200-15 contraceptive patch

Depomed announces SPA agreement with FDA for Serada Phase 3 trial for menopausal hot flashes

OptiNose's bi-directional nasal device delivering fluticasone effective in reducing nasal polyps in CRS patients

Elan to offer $200 million in aggregate principal amount of 8.75% senior notes due 2016

Sinobiopharma inks agreement with Lianhuan to co-develop, manufacture and commercialize Eplerenone

Columbia Laboratories announces repurchase of 3.3 million common stock

Scientists develop new method to enable drug release inside cancer cells

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