Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

FoxOs shown to be potential new targets for cancer drugs

In an elegant, multiple-gene knockout experiment, a team of Boston scientists has discovered that a trio of molecules, called FoxOs, are fundamentally critical in preventing some cancers, maintaining blood vessel stability, and in keeping blood-forming stem cells healthy.

29 Jan 2007

Manipulation of proliferation and differentiation of human bone marrow derived neural stem cells in vitro and in vivo

Stem cells taken from adult human bone marrow have been manipulated by scientists at the Maxine Dunitz Neurosurgical Institute at Cedars-Sinai Medical Center to generate aggregates of cells called spheres that are similar to those derived from neural stem cells of the brain.

28 Jan 2007

New drug to combat Gastrointestinal graft-vs.-host disease in stem-cell patients shows significant reduction in deaths

Gastrointestinal graft-vs.-host disease is a common and potentially deadly side effect for patients who undergo an allogeneic stem-cell transplant to treat certain blood cancers.

23 Jan 2007

FDA issues guidance on license applications for placental/umbilical cord blood products

The Food and Drug Administration (FDA) has issued a draft guidance recommending a streamlined path to licensure for establishments that manufacture cord blood for certain medical conditions.

16 Jan 2007

Selective marker found to indicate aggressive form of breast cancer

Researchers have linked a structural protein called nestin to a particularly deadly form of breast cancer, identifying a new biomarker that could lead to earlier detection and better treatment.

16 Jan 2007

Stem cell research discovery could mean 'big things' for cancer

A new discovery in stem cell research may mean big things for cancer patients in the future. Gary Van Zant, Ph.D., and a research team at the University of Kentucky published their findings in Nature Genetics.

14 Jan 2007

Retinoblastoma gene may play a critical role in the development of the placenta

An important cancer-related gene may play a critical role in the development of the placenta, the organ that controls nutrient and oxygen exchange between a mother and her fetus during pregnancy, and perhaps in miscarriages.

10 Jan 2007

New embryonic cell discovery

Cambridge scientists have discovered the stage at which some of the cells of a fertilised mammalian egg are fated to develop into stem cells and why this occurs.

10 Jan 2007

Stem cells derived from human amniotic fluid appear to offer many of the benefits of embryonic stem cells

...including the ability to grow into brain, muscle, bone and other tissues -- according to a study published in the Jan. 7 online edition on the journal Nature Biotechnology, the Washington Post reports.

9 Jan 2007

BIO urges Congress to pass Stem Cell Research Enhancement Act

Jim Greenwood, president and CEO of the Biotechnology Industry Organization (BIO), has issued the following statement on H.R. 3, the Stem Cell Research Enhancement Act of 2007.

9 Jan 2007

Virginia Democrats want to approve embryonic stem cell research, ban therapeutic cloning

Democrats in the Virginia General Assembly plan to propose legislation that would authorize human embryonic stem cell research in the state, Jesse Furgeson, spokesperson for state House Democratic Caucus Chair Brian Moran, said recently, the Richmond Times-Dispatch reports.

9 Jan 2007

House to vote on expansion of funding for human embryonic stem cell research

The House later this week plans to vote on a measure (HR 3, S 5) -- called the Stem Cell Research Enhancement Act of 2007 -- that would expand federal funding for human embryonic stem cell research, CQ HealthBeat reports.

9 Jan 2007

A Trojan horse for gliomas

Gliomas are a group of brain tumors where the most common type is also the most aggressive one.

9 Jan 2007

Retinoblastoma gene may play a critical role in the development of the placenta

9 Jan 2007

Cell therapy for Parkinson's

Parkinson's disease is one of the commonest afflictions caused by damage to the nerve cells of the brain. Patients suffer from muscular tremors and rigidity, and their movements are severely impaired.

8 Jan 2007

Stem cells from amniotic fluid no substitute for embryonic cells

The Genetics Policy Institute (GPI) applauds the discovery of apparently versatile stem cells in amniotic fluid as a positive development, but cautions that the research does not eliminate the need for embryonic stem cell research.

8 Jan 2007

Abnormal hair development and apparent follicular transformation to mammary gland in the absence of Hedgehog signaling

One single molecule determines how stem cells in the hair follicle develop. A study at the Sahlgrenska Academy at Göteborg University in Sweden has shown that cells that should give rise to hair can instead give rise to mammary gland cells in mice who lack this molecule.

8 Jan 2007

Democrats plan to introduce bills addressing stem cell research, Rx benefit

House Democrats plan to introduce bills that would reduce restrictions on federal funding for embryonic stem cell research and allow HHS to negotiate directly with pharmaceutical companies on prices for medications under the Medicare prescription drug benefit, incoming House Majority Leader Steny Hoyer (D-Md.) said on Wednesday, CQ Today reports.

7 Jan 2007

56% of adults support easing federal embryonic stem cell research funding restrictions

About 56% of U.S. adults support easing restrictions on federal funding for human embryonic stem cell research, according to an Associated Press-AOL poll conducted from Dec. 19, 2006, to Dec. 21, 2006, the AP/Washington Post reports (Superville, AP/Washington Post, 1/3).

7 Jan 2007

Uric acid holds potential for central nervous system damage

Uric acid is commonly associated with the excruciatingly painful joint disease known as gout, but it can also play a crucial role in the treatment of spinal cord injury and other central nervous system disorders, such as stroke, multiple sclerosis and Parkinson's disease, according to Rutgers' Bonnie Firestein.

3 Jan 2007