Dysbiosis News and Research

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Dysbiosis is a condition caused by an imbalance in the bacterial community (microbiome) of the human gut. Dysbiosis disrupts the ecoystsem of the gut, resulting in symptoms such as diarrhea, constipation, bloating, and indigestion, among others.

Heated tobacco and cigarettes cause the same gut and vascular damage, study finds

Italian researchers found that both heated tobacco products (HTPs) and conventional cigarettes trigger oxidative stress, endotoxemia, and gut barrier disruption in adults and children. The findings challenge the perception that HTPs are a safer alternative to smoking.

3 Nov 2025

Exploring the gut-brain-immune axis in neurodegeneration

Neurodegenerative diseases (NDs), such as Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), and multiple sclerosis (MS), represent a growing global health burden, particularly in aging populations.

28 Oct 2025

Scientists uncover the gut’s hidden hydrogen engine and how it falters in Crohn’s disease

Study reveals that group B [FeFe]-hydrogenase is the primary enzyme driving fermentative hydrogen production in the healthy human gut, mainly through Bacteroides species. These genes are significantly depleted in Crohn’s disease, indicating a metabolic shift and altered hydrogen cycling dominated by respiratory bacteria

27 Oct 2025

People with multiple sclerosis found to have dysbiotic oral microbiome

With ads everywhere for pro- or pre-biotic foods and supplements, most people are familiar with the gut microbiome-the trillions of bacteria, fungi, and viruses that colonize our digestive tract-and the idea that keeping our gut microbiome healthy improves our overall health.

22 Oct 2025

Night shift work may raise risk of irritable bowel syndrome

The study indicates that night shift work increases irritable bowel syndrome risk, particularly among those with obesity, due to circadian rhythm disturbances.

22 Oct 2025

Study links gut dysbiosis with severe steatosis in MASLD

A new study in eGastroenterology links gut dysbiosis with severe steatosis in metabolic dysfunction–associated steatotic liver disease (MASLD).

15 Oct 2025

How shifting antibodies fuel aging and the new therapies aiming to slow it

This review uncovers how aging reshapes immunoglobulins, particularly IgG, IgM, and IgA, driving inflammation, cellular senescence, and tissue degeneration. By dissecting B-cell dysfunction, glycosylation changes, and Fc receptor pathways, it reveals immunoglobulins as both biomarkers and potential therapeutic targets in aging.

14 Oct 2025

Western diet fuels IBD by derailing the microbiome - can precision nutrition turn the tide?

This review examines how Western dietary patterns, high in ultra-processed foods, salt, and unhealthy fats, disrupt gut microbiota, impair immune regulation, and contribute to the global rise of inflammatory bowel disease (IBD). It highlights systems biology and nutritional epidemiology as essential tools to develop personalised dietary strategies and shift IBD care from treatment to prevention.

12 Oct 2025

Innovative approaches target PAR2 receptor to alleviate gut pain

Abdominal pain is a hallmark of many digestive disorders, including inflammatory bowel disease and irritable bowel syndrome.

7 Oct 2025

Coffee protects the liver by blocking inflammation and scarring, review finds

A new review in Biochemical Pharmacology synthesizes decades of research showing consistent links between regular coffee consumption and reduced risk of liver disease, including cirrhosis and liver cancer. Coffee’s bioactive compounds act on antioxidant, anti-inflammatory, antifibrotic, and metabolic pathways to slow liver damage progression.

21 Sep 2025

Study reveals how ozone exerts multi-organ effects by disturbing the lung-liver connection

Ozone pollution is rising worldwide, frequently exceeding safety thresholds in urban centers and industrial regions. Its health risks are well-documented: breathing ozone can worsen asthma, damage airways, and increase the risk of cardiovascular and neurological disorders.

17 Sep 2025

What diet pattern worsens inflammatory bowel disease?

Researchers compare the different effects of pro-inflammatory dietary patterns on inflammatory bowel disease severity.

9 Sep 2025

Frailty and microbial imbalance drive GI complications in bladder cancer surgery

Gastrointestinal (GI) complications, such as postoperative ileus (POI) and intra-abdominal infections (IAI), remain a major concern after radical cystectomy for bladder cancer.

8 Sep 2025

How fiber intake shapes your gut microbes’ digestion strategy

A study reveals how gut bacteria shift from fiber to mucus digestion, linking this change to inflammation in healthy adults and introducing the Muc2Plant ratio.

5 Sep 2025

Research reveals molecular details of ME/CFS and long COVID

Patients with chronic fatigue syndrome/myalgic encephalomyelitis (ME/CFS) have heightened innate immune responses to bacteria, viruses, and fungi. While these responses are essential to fight infection, they can cause damage when unchecked.

1 Sep 2025

Can the gut microbiome adapt to protect the brain after stroke?

Alterations in gut microbiota post-stroke may drive metabolic changes, presenting opportunities for innovative therapeutic strategies in acute stroke recovery.

28 Aug 2025

Can diet alone slow brain aging? Scientists say evidence is still too weak

Researchers reviewing evidence in the Annual Review of Nutrition find that healthy dietary patterns may support brain aging, but caution that scientific enthusiasm currently outpaces solid proof. Multidomain strategies combining diet with exercise, cognitive training, and vascular health show greater promise.

25 Aug 2025

Gut bacteria and insomnia influence each other in small but significant ways, study shows

Scientists used Mendelian randomisation to explore the two-way relationship between gut microbiota and insomnia, analyzing GWAS data from over 386,000 individuals and two major microbiome cohorts. The study found only limited taxa surviving strict correction, suggesting small but causal links that highlight the gut–brain axis in sleep health.

21 Aug 2025

Fasting supports type 1 diabetes care by reshaping the microbiome

A week of fasting alters the gut microbiome in type 1 diabetes, aligning it with healthy profiles and enhancing cholesterol and weight management.

20 Aug 2025

Could chlorophyll become the next antidiabetic therapy?

Research highlights chlorophyll's role in blood sugar regulation and insulin mimicry, though safety risks and lack of human trials warrant caution.