ACE Inhibitors News and Research

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ACE inhibitors act to reduce hypertension by interfering with the conversion of angiotensin I to artery-constricting angiotensin II. Blocking the production of angiotensin II results in arterial vasodilation and an accompanying reduction in blood pressure. ACE inhibitors currently are recommended as first-line therapy for hypertension in certain patient populations, because of their safety and efficacy.

Study finds ACE inhibitors linked to increased risk of recurrence in women who have had breast cancer

ACE inhibitors, commonly used to control high blood pressure and heart failure in women, may be associated with an increased risk of recurrence in women who have had breast cancer, according to a study by researchers at UCLA's Jonsson Comprehensive Cancer Center.

21 Apr 2011

America’s best loved drugs: Report

According to the latest report from consulting firm IMS Health, Americans are consuming a lot of prescription drugs. And they seem especially fond of those to lower their cholesterol, relieve heartburn, aid in depressive disorders and lessen pain. Overall, however, their spending on such drugs is slowing.

20 Apr 2011

Cardioxyl's CXL-1020 preclinical data against heart failure presented at ACC meeting

Cardioxyl Pharmaceuticals, Inc. announced today that it is presenting two abstracts from studies of its lead clinical candidate, CXL-1020, at the American College of Cardiology's 60th Annual Scientific Session & Expo in New Orleans, Louisiana.

5 Apr 2011

Singing reduces blood pressure prior to total knee replacement surgery

Doctors report that singing reduced the blood pressure of a 76-year-old woman who had experienced severe preoperative hypertension prior to total knee replacement surgery for osteoarthritis (OA). While the patient was unresponsive to aggressive pharmacologic interventions, the woman's blood pressure dropped dramatically when she sang several religious songs.

30 Mar 2011

Multivitamin supplements can optimize body's metabolic performance

Eating well is a difficult task for most people given the frantic pace of everyday living. Convenient pre-packaged and fast foods, rich in calories and low in nutrients, offer an easy solution to those short on time, but neglect to provide daily essential nutrients. And the short-changing of necessary nutritional requirements for good health is furthered by routine stress itself.

22 Mar 2011

Study to measure lower pressure's impact on kidney disease, cognitive function

Georgia Health Sciences University is enrolling patients in a federally funded study to determine if a lower blood pressure reduces the progression of kidney disease.

22 Mar 2011

WHO concerned about radiation levels in food near damaged Japanese nuclear plant

A WHO spokesperson "said on Monday that the detection of radiation in food after an earthquake damaged a Japanese nuclear plant was a more serious problem than had first expected," Reuters reports.

22 Mar 2011

ACE, ARB combination therapy may increase risk of kidney failure, death

Elderly patients prescribed combination angiotensin converting enzyme inhibitors and angiotensin receptor blockers had a higher risk of kidney failure and death, according to a study published in CMAJ.

22 Mar 2011

High blood pressure medications useful even in those without hypertension: Study

Researchers have studied existing evidence to suggest that people who have had a stroke or a heart attack might benefit from taking blood pressure medications, even if they do not have high blood. They noted that for every 1,000 people taking the drugs in clinical trials, on average 15 fewer died from heart disease than when the patients got dummy treatment. The study however could not explain the cause for this benefit. The study, which was funded by Tulane University and the National Institutes of Health, was published in the March 2 issue of the Journal of the American Medical Association.

1 Mar 2011

How cocoa in chocolate reduces risk of heart disease

In time for the chocolate-giving and chocolate-noshing fest on Valentine's Day, scientists are reporting discovery of how this treat boosts the body's production of high-density lipoprotein cholesterol (HDL) - the "good" form of cholesterol that protects against heart disease.

8 Feb 2011

Researchers find kidney-specific gene defects may increase risk of heart failure

Scientists have identified the first DNA sequence variant common in the population that is not only associated with an increased risk of heart failure, but appears to play a role in causing it.

18 Jan 2011

Metabolon announces publication of 'Metabolomic Distinction and Insights into the Pathogenesis of Human Primary Dilated Cardiomyopathy'

Metabolon, the leader in metabolomics, biomarker discovery and analysis, announces the publication of "Metabolomic Distinction and Insights into the Pathogenesis of Human Primary Dilated Cardiomyopathy", in the European Journal of Clinical Investigation.

6 Jan 2011

AHA recognizes UC Irvine Medical Center's commitment to high-quality cardiac care

The American Heart Association has recognized UC Irvine Healthcare's commitment to the highest standards of care for heart failure patients.

17 Dec 2010

Diuretic lessens risk of death from mild heart failure: Study

A new study shows that diuretic pill Inspra (generic – Eplerenone) cuts down the risk of death and hospitalization among people with mild heart failure. The drug that is widely used to treat advanced heart failure, also has value for people with mild disease, says lead researcher Faiez Zannad, of Nancy University in Nancy, France. The results were reported at the American Heart Association's annual meeting and published simultaneously online in the New England Journal of Medicine.

16 Nov 2010

Dialysis patients at elevated risk for sudden cardiac death: Study

Approximately 500,000 Americans require dialysis to treat kidney disease; of that population nearly half of the deaths that occur are caused by cardiovascular disease. Dialysis patients are at elevated risk for sudden cardiac death, but physicians are unclear why these deaths occur because little research has been done to examine how to best manage heart disease in this high-risk population.

15 Nov 2010

NCKU develops novel stem cell therapy for heart repair

Assistant Prof. Patrick C. H. Hsieh of Institute of Nanotechnology and Microsystems Engineering, College of Medicine, National Cheng Kung University (NCKU), Tainan, Taiwan, has led a research team of myocardial regeneration to conduct an experiment on pigs and has proved that by combining self-assembling peptide nanofiber hydrogel with autologous bone marrow stem cell, myocardial protection after acute myocardial infarction, vascular regeneration and heart functions can be improved.

12 Oct 2010

Study reveals fine-tuning mechanism of angiotensinogen in pre-eclampsia

An exciting collaboration between the Universities of Cambridge and Nottingham has resulted in new insights into the hypertension that frequently blights pregnancy.

7 Oct 2010

Research findings likely to have significant implications for treatment of pre-eclampsia, hypertension

Scientists have discovered a mechanism which raises blood pressure in pre-eclampsia, a potentially deadly condition which occurs during pregnancy.

7 Oct 2010

DecImmune Therapeutics receives funds to improve ischemia reperfusion injury outcomes

DecImmune Therapeutics announced today that it has received a $1 million equity investment from Astellas Venture Management and has additionally been awarded $2.2 million in Phase II SBIR funding from the National Institutes of Health.

28 Sep 2010

Researchers investigate performance levels of resident and staff physicians

Research on the quality of US resident physician performance levels has often been limited by lack of a comparison group or strict focus on specific diseases and geographical areas. In order to gain insight on differences in quality of care provided by resident physicians versus staff physicians, Boston Medical Center and Palo Alto Medical Foundation researchers investigated performance of physicians in 33,900 hospital-based outpatient visits throughout the US.

22 Sep 2010

ACE Inhibitors News and Research

Further Reading

Study finds ACE inhibitors linked to increased risk of recurrence in women who have had breast cancer

America’s best loved drugs: Report

Cardioxyl's CXL-1020 preclinical data against heart failure presented at ACC meeting

Singing reduces blood pressure prior to total knee replacement surgery

Multivitamin supplements can optimize body's metabolic performance

Study to measure lower pressure's impact on kidney disease, cognitive function

WHO concerned about radiation levels in food near damaged Japanese nuclear plant

ACE, ARB combination therapy may increase risk of kidney failure, death

High blood pressure medications useful even in those without hypertension: Study

How cocoa in chocolate reduces risk of heart disease

Researchers find kidney-specific gene defects may increase risk of heart failure

Metabolon announces publication of 'Metabolomic Distinction and Insights into the Pathogenesis of Human Primary Dilated Cardiomyopathy'

AHA recognizes UC Irvine Medical Center's commitment to high-quality cardiac care

Diuretic lessens risk of death from mild heart failure: Study

Dialysis patients at elevated risk for sudden cardiac death: Study

NCKU develops novel stem cell therapy for heart repair

Study reveals fine-tuning mechanism of angiotensinogen in pre-eclampsia

Research findings likely to have significant implications for treatment of pre-eclampsia, hypertension

DecImmune Therapeutics receives funds to improve ischemia reperfusion injury outcomes

Researchers investigate performance levels of resident and staff physicians

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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